Recent PDB releases or updates: week of 23 May 2008
- 1j3n.pdb.
transferase 10-feb-03 1j3n
Mg
Title: crystal structure of 3-oxoacyl-(acyl-carrier protein) synthase ii from thermus thermophilus hb8
Author: b. bagautdinov, m. miyano, t. h. tahirov, riken structural genomics/proteomics initiative (rsgi)
Keywords: fatty acid elongation, acyl-carrier protein (acp), beta-keto-acp synthase (kas), homodimer, structural genomics, riken structural genomics/proteomics initiative, rsgi, transferase
- 1mki.pdb.
hydrolase 29-aug-02 1mki
Se
Title: crystal structure of bacillus subtilis probable glutaminase, apc1040
Author: y. kim, i. dementieva, e. vinokour, a. joachimiak, midwest center for structural genomics (mcsg)
Keywords: probable glutaminase, psi, protein structure initiative, midwest center for structural genomics, mcsg, hydrolase
- 1r5b.pdb.
translation 10-oct-03 1r5b
Title: crystal structure analysis of sup35
Author: c. kong, h. song
Keywords: peptide release, gtpase
- 1rp0.pdb.
biosynthetic protein 02-dec-03 1rp0
Zn
Title: crystal structure of thi1 protein from arabidopsis thaliana
Author: p. h. c. godoi, m. a. van sluys, c. f. m. menck, g. oliva
Keywords: biosynthetic protein
- 1u60.pdb.
hydrolase 28-jul-04 1u60
Title: mcsg apc5046 probable glutaminase ybas
Author: c. chang, m. e. cuff, a. joachimiak, a. savchenko, a. edwards, t. skarina, midwest center for structural genomics, midwest center for structural genomics (mcsg)
Keywords: apc5046, psi, protein structure initiative, midwest center for structural genomics, mcsg, hydrolase
- 1uw4.pdb.
rna-binding protein 29-jan-04 1uw4
Title: the structural basis of the interaction between nonsense mediated decay factors upf2 and upf3
Author: j. kadlec, e. izaurralde, s. cusack
Keywords: rna-binding protein, nmd, rnp domain, mif4g domain
- 1w0z.pdb.
hydrolase 15-jun-04 1w0z
Title: urokinase type plasminogen activator
Author: u. jacob
Keywords: hydrolase, plasminogen activator
- 1w10.pdb.
hydrolase 15-jun-04 1w10
Title: urokinase type plasminogen activator
Author: u. jacob
Keywords: hydrolase, plasminogen activator
- 1w11.pdb.
hydrolase 15-jun-04 1w11
Title: urokinase type plasminogen activator
Author: u. jacob
Keywords: hydrolase, plasminogen activator
- 1w12.pdb.
hydrolase 15-jun-04 1w12
Title: urokinase type plasminogen activator
Author: u. jacob
Keywords: hydrolase, plasminogen activator
- 1w13.pdb.
hydrolase 15-jun-04 1w13
Title: urokinase type plasminogen activator
Author: u. jacob
Keywords: hydrolase, plasminogen activator
- 1w14.pdb.
hydrolase 15-jun-04 1w14
Title: urokinase type plasminogen activator
Author: u. jacob
Keywords: hydrolase, plasminogen activator
- 1w9m.pdb.
oxidoreductase 14-oct-04 1w9m
Fe
Title: as-isolated hybrid cluster protein from desulfovibrio vulgaris x-ray structure at 1.35a resolution using iron anomalous signal
Author: d. aragao, s. macedo, e. p. mitchell, d. coelho, c. v. romao, m. teixeira, p. f. lindley
Keywords: anaerobic, oxidised, as-isolated, desulfovibrio vulgaris, oxidoreductase
- 1xf1.pdb.
hydrolase 13-sep-04 1xf1
Ca Se
Title: structure of c5a peptidase- a key virulence factor from streptococcus
Author: c. k. brown, z. y. gu, p. p. cleary, y. matsuka, s. olmstead, d. h. ohlendorf, c. a. earhart
Keywords: hydrolase
- 1yk9.pdb.
lyase 17-jan-05 1yk9
Title: crystal structure of a mutant form of the mycobacterial adenylyl cyclase rv1625c
Author: a. d. ketkar, a. r. shenoy, u. a. ramagopal, s. s. visweswariah, k. suguna, tb structural genomics consortium (tbsgc)
Keywords: structural genomics, psi, protein structure initiative, tb structural genomics consortium, tbsgc, lyase
- 1ykt.pdb.
hydrolase 18-jan-05 1ykt
Ca
Title: trypsin/bpti complex mutant
Author: c. k. brown, d. h. ohlendorf
Keywords: trypsin, mutant, hydrolase
- 1ylc.pdb.
hydrolase/inhibitor 19-jan-05 1ylc
Ca
Title: trypsin/bpti complex mutant
Author: c. k. brown, d. h. ohlendorf
Keywords: pancreatic trypsin inhibitor, bpti, hydrolase/inhibitor complex
- 1yld.pdb.
hydrolase/inhibitor 19-jan-05 1yld
Ca
Title: trypsin/bpti complex mutant
Author: c. k. brown, d. h. ohlendorf
Keywords: trypsin, complex, hydrolase/inhibitor complex
- 1z4r.pdb.
transferase 16-mar-05 1z4r
Title: human gcn5 acetyltransferase
Author: a. dong, g. bernstein, a. schuetz, t. antoshenko, h. wu, p. loppnau, m. sundstrom, c. arrowsmith, a. edwards, a. bochkarev, a. plotnikov, structural genomics consortium (sgc)
Keywords: acetyltransferase, sgc, structural genomics, structural genomics consortium
- 1zxf.pdb.
toxin 08-jun-05 1zxf
He Hg
(NMR, 20 structures)
Title: solution structure of a self-sacrificing resistance protein, calc from micromonospora echinospora
Author: s. singh, m. h. hager, c. zhang, b. r. griffith, m. s. lee, k. hallenga, j. l. markley, j. s. thorson, center for eukaryotic structural genomics (cesg)
Keywords: structural genomics, psi, protein structure initiative, center for eukaryotic structural genomics, cesg, toxin
- 2a8b.pdb.
hydrolase 07-jul-05 2a8b
Cl
Title: crystal structure of the catalytic domain of human tyrosine phosphatase receptor, type r
Author: e. ugochukwu, j. eswaran, a. barr, e. longman, c. arrowsmith, a. edwards, m. sundstrom, f. von delft, s. knapp, structural genomics consortium (sgc)
Keywords: receptor, human, structural genomics, structural genomics consortium, sgc, hydrolase
- 2aft.pdb.
hydrolase activator, protein binding 26-jul-05 2aft
Ca
Title: formylglycine generating enzyme c336s mutant
Author: d. roeser, m. g. rudolph
Keywords: post-translational modification, endoplasmic reticulum, sulfatase, hydrolase activator, protein binding
- 2afy.pdb.
hydrolase activator, protein binding 26-jul-05 2afy
Ca
Title: formylglycine generating enzyme c341s mutant
Author: d. roeser, m. g. rudolph
Keywords: post-translational modification, endoplasmic reticulum, sulfatase, hydrolase activator, protein binding
- 2aii.pdb.
hydrolase activator,protein binding 29-jul-05 2aii
Ca
Title: wild-type formylglycine generating enzyme reacted with iodoacetamide
Author: d. roeser, m. g. rudolph
Keywords: post-translational modification, endoplasmic reticulum, sulfatase, hydrolase activator,protein binding
- 2aij.pdb.
hydrolase activator,protein binding 29-jul-05 2aij
Cl Ca
Title: formylglycine generating enzyme c336s mutant covalently bound to substrate peptide ctpsr
Author: d. roeser, m. g. rudolph
Keywords: post-translational modification, endoplasmic reticulum, sulfatase, hydrolase activator,protein binding
- 2aik.pdb.
hydrolase activator,protein binding 29-jul-05 2aik
Cl Ca
Title: formylglycine generating enzyme c336s mutant covalently bound to substrate peptide lctpsra
Author: d. roeser, m. g. rudolph
Keywords: post-translational modification, endoplasmic reticulum, sulfatase, hydrolase activator,protein binding
- 2b0f.pdb.
hydrolase 13-sep-05 2b0f
He Hg
(NMR, 20 structures)
Title: nmr structure of the human rhinovirus 3c protease (serotype 14) with covalently bound ace-lealfq-ethylpropionate inhibitor
Author: t. c. bjorndahl, l. c. andrew, d. s. wishart
Keywords: protein-inhibitor complex, hydrolase
- 2b4g.pdb.
oxidoreductase 23-sep-05 2b4g
Br
Title: dihydroorotate dehydrogenase
Author: t. l. arakaki, e. a. merritt, structural genomics of pathogenic protozoa consortium (sgpp)
Keywords: psi, protein structure initiative, structural genomics of pathogenic protozoa consortium, sgpp, oxidoreductase
- 2bpd.pdb.
receptor 19-apr-05 2bpd
Title: structure of murine dectin-1
Author: j. brown, c. a. o'callaghan, a. s. j. marshall, r. j. c. gilbert, c. siebold, s. gordon, g. d. brown, e. y. jones
Keywords: dectin-1, beta-glucan, fungal recognition, c-type lectin-like domain, ctld, carbohydrate
- 2bpe.pdb.
receptor 19-apr-05 2bpe
Cl Ca
Title: structure of murine dectin-1
Author: j. brown, c. a. o'callaghan, a. s. j. marshall, r. j. c. gilbert, c. siebold, s. gordon, g. d. brown, e. y. jones
Keywords: dectin-1, beta-glucan, fungal recognition, c-type lectin-like domain, ctld
- 2bph.pdb.
receptor 19-apr-05 2bph
Mg
Title: structure of murine dectin-1
Author: j. brown, c. a. o'callaghan, a. s. j. marshall, r. j. c. gilbert, c. siebold, s. gordon, g. d. brown, e. y. jones
Keywords: dectin-1, beta-glucan, fungal recognition, c-type lectin-like domain, ctld, carbohydrate
- 2cl8.pdb.
receptor 26-apr-06 2cl8
Cl Ca
Title: dectin-1 in complex with beta-glucan
Author: j. brown, c. a. o'callaghan, a. s. j. marshall, r. j. c. gilbert, c. siebold, s. gordon, g. d. brown, e. y. jones
Keywords: fungal recognition, ctld, receptor, dectin-1, laminarin, beta-glucan, c-type lectin-like domain
- 2dqc.pdb.
immune system/hydrolase 25-may-06 2dqc
Title: crystal structure of hyhel-10 fv mutant(hy33f) complexed with hen egg lysozyme
Author: m. shiroishi, h. kondo, k. tsumoto, i. kumagai
Keywords: mutant, immune system/hydrolase complex
- 2dqd.pdb.
immune system/hydrolase 25-may-06 2dqd
Title: crystal structure of hyhel-10 fv mutant (hy50f) complexed with hen egg lysozyme
Author: m. shiroishi, h. kondo, k. tsumoto, i. kumagai
Keywords: mutant, immune system/hydrolase complex
- 2dqe.pdb.
immune system/hydrolase 25-may-06 2dqe
Title: crystal structure of hyhel-10 fv mutant (hy53a) complexed with hen egg lysozyme
Author: m. shiroishi, h. kondo, k. tsumoto, i. kumagai
Keywords: mutant, immune system/hydrolase complex
- 2dqf.pdb.
immune system/hydrolase 25-may-06 2dqf
Title: crystal structure of hyhel-10 fv mutant (y33ay53a) complexed with hen egg lysozyme
Author: m. shiroishi, h. kondo, k. tsumoto, i. kumagai
Keywords: mutant, immune system/hydrolase complex
- 2e3w.pdb.
hydrolase 30-nov-06 2e3w
Cl
Title: x-ray structure of native rnase a
Author: d. j. boerema, v. a. tereshko, s. b. h. kent
Keywords: beta-sheet, hydrolase
- 2f2v.pdb.
signaling protein 18-nov-05 2f2v
Title: alpha-spectrin sh3 domain a56g mutant
Author: a. camara-artigas, f. conejero-lara, s. casares, o. lopez-mayorga, c. vega
Keywords: signaling protein
- 2f2w.pdb.
signaling protein 18-nov-05 2f2w
Title: alpha-spectrin sh3 domain r21a mutant
Author: a. camara-artigas, f. conejero-lara, s. casares, o. lopez-mayorga, c. vega
Keywords: signaling protein
- 2f2x.pdb.
signaling protein 18-nov-05 2f2x
Title: alpha-spectrin sh3 domain r21g mutant
Author: a. camara-artigas, f. conejero-lara, s. casares, o. lopez-mayorga, c. vega
Keywords: signaling protein
- 2fe1.pdb.
structural genomics, unknown function 15-dec-05 2fe1
Cl Mn Ca
Title: crystal structure of pae0151 from pyrobaculum aerophilum
Author: r. d. bunker, e. n. baker, v. l. arcus
Keywords: structural genomics, unknown function
- 2flh.pdb.
plant protein 06-jan-06 2flh
Na
Title: crystal structure of cytokinin-specific binding protein from mung bean in complex with cytokinin
Author: o. pasternak, g. d. bujacz, m. m. sikorski, m. jaskolski
Keywords: zeatin, pathogenesis-related proteins, multiple- ligand binding, plant protein
- 2fwn.pdb.
lyase 02-feb-06 2fwn
Mg Ca
Title: phosphorylation of an active site serine in a thdp- dependent enzyme by phosphonate inactivation
Author: a. k. bera, m. s. hasson
Keywords: carbon-carbon, decarboxylase, phophonated, mandelate catabolism,thiamine diphosphate, high resolution
- 2fxp.pdb.
virus/viral protein 06-feb-06 2fxp
He Hg
(NMR, minimized average structure)
Title: solution structure of the sars-coronavirus hr2 domain
Author: m. caffrey, s. hakansson-mcreynolds, s. jiang
Keywords: trimer, coiled-coil, virus/viral protein complex
- 2fzv.pdb.
structural genomics, unknown function 10-feb-06 2fzv
Cl Ca
Title: crystal structure of an apo form of a flavin-binding protein from shigella flexneri
Author: i. i. vorontsov, g. minasov, j. s. brunzelle, l. shuvalova, f. r. collart, w. f. anderson, midwest center for structural genomics (mcsg)
Keywords: flavin binding protein, structural genomics, psi, protein structure initiative, midwest center for structural genomics, mcsg, structural genomics, unknown function
- 2g18.pdb.
oxidoreductase 13-feb-06 2g18
Ca
Title: crystal structure of nostoc sp. 7120 phycocyanobilin:ferredoxin oxidoreductase (pcya) apoprotein
Author: s. -l. tu, j. c. lagarias, a. j. fisher
Keywords: oxidoreductase
- 2g86.pdb.
transferase 01-mar-06 2g86
Title: l. casei thymidylate synthase y261f in complex with substrate, dump
Author: j. s. finer-moore, r. m. stroud
Keywords: dump complex, thymidylate synthase mutant, transferase
- 2g89.pdb.
transferase 02-mar-06 2g89
Title: l. casei thymidylate synthase y261a in complex with substrate, dump
Author: j. s. finer-moore, r. m. stroud
Keywords: beta sheet, dump-binding residue, dump complex, active site mutation, transferase
- 2g8a.pdb.
transferase 02-mar-06 2g8a
Title: lactobacillus casei y261m in complex with substrate, dump
Author: j. s. finer-moore, r. m. stroud
Keywords: alpha-beta protein, dump complex, active site mutation, methyltransferase
- 2g8d.pdb.
transferase 02-mar-06 2g8d
Title: lactobacillus casei thymidylate synthase y261w-dump complex
Author: j. s. finer-moore, r. m. stroud
Keywords: alpha/beta protein, methyltransferase, dump complex, active site mutation
- 2g8m.pdb.
transferase 02-mar-06 2g8m
Title: escherichia coli thymidylate synthase y209w in complex with substrate, dump, and a cofactor analog, cb3717
Author: t. t. lee, z. newby, r. m. stroud
Keywords: alpha/beta protein, ternary complex, dump, antifolate, dump binding site mutant, transferase
- 2g8o.pdb.
transferase 02-mar-06 2g8o
Title: high resolution structure of escherichia coli thymidylate synthase ternary complex with dump and a cofactor analog, cb3717
Author: z. newby, t. t. lee, r. m. stroud
Keywords: dump, antifolate, high-resolution, ternary complex, beta sheet, alpha/beta protein
- 2gp3.pdb.
metal binding protein 16-apr-06 2gp3
Zn Fe
Title: crystal structure of the catalytic core comain of jmjd2a
Author: z. chen, j. zang, j. whetstine, x. hong, f. davrazou, t. g. kutateladze, m. simpson, s. dai, j. hagman, y. shi, g. zhang
Keywords: zinc finger, metal binding protein
- 2gp5.pdb.
metal binding protein 16-apr-06 2gp5
Zn Fe
Title: crystal structure of catalytic core domain of jmjd2a complexed with alpha-ketoglutarate
Author: z. chen, j. zang, j. whetstine, x. hong, f. davrazou, t. g. kutateladze, m. simpson, s. dai, j. hagman, y. shi, g. zhang
Keywords: zinc finger, metal binding protein
- 2gx8.pdb.
structural genomics, unknown function 08-may-06 2gx8
Zn
Title: the crystal stucture of bacillus cereus protein related to nif3
Author: g. minasov, j. s. brunzelle, l. shuvalova, i. i. vorontsov, f. r. collart, w. f. anderson, mcsg, midwest center for structural genomics (mcsg)
Keywords: structural genomics, unknown function, nif3 related protein, psi, protein structure initiative, midwest center for structural genomics, mcsg
- 2gzq.pdb.
lipid binding protein 11-may-06 2gzq
Se
Title: phosphatidylethanolamine-binding protein from plasmodium vivax
Author: t. l. arakaki, e. a. merritt, structural genomics of pathogenic protozoa consortium (sgpp)
Keywords: psi, protein structure initiative, structural genomics of pathogenic protozoa consortium, sgpp, lipid binding protein
- 2hin.pdb.
transcription 29-jun-06 2hin
Title: structure of n15 cro at 1.05 a: an ortholog of lambda cro with a completely different but equally effective dimerization mechanism
Author: m. s. dubrava, w. m. ingram, s. a. roberts, a. weichsel, w. r. montfort, m. h. cordes
Keywords: dimer interface, helix-turn-helix
- 2ili.pdb.
lyase 02-oct-06 2ili
Zn
Title: refine atomic structure of human carbonic anhydrase ii
Author: s. z. fisher
Keywords: proton shuttle, carbonic anhydrase, lyase
- 2itk.pdb.
isomerase 19-oct-06 2itk
Title: human pin1 bound to d-peptide
Author: j. p. noel, y. zhang
Keywords: isomerase, ww domain
- 2jpf.pdb.
structural genomics 10-may-07 2jpf
He Hg
(NMR, 20 structures)
Title: bpp3783_115-220
Author: g. s. shaw, m. j. revington, a. savichenko, c. h. arrowsmith, ontario centre for structural proteomics (ocsp)
Keywords: type iii secretion effector protein, structural genomics, ontario centre for structural proteomics, ocsp
- 2jqd.pdb.
gene regulation, protein binding 31-may-07 2jqd
He Hg
(NMR, 10 structures)
Title: structure of the leucine-rich repeat domain of lanp
Author: c. de chiara, a. pastore
Keywords: lrr domain, phosphoprotein, pp2a inhibitor, tumor suppression, transcriptional regulation, rna shuttling, apoptosis, cerebellar morphogenesis, gene regulation, protein binding
- 2jss.pdb.
chaperone/nuclear protein 11-jul-07 2jss
He Hg
(NMR, 10 structures)
Title: nmr structure of chaperone chz1 complexed with histone h2a.z-h2b
Author: z. zhou, h. feng, f. d. hansen, e. luk, h. kato, d. freedberg, l. e. key, c. wu, y. bai
Keywords: intrinsically unfolded protein, chaperone/structural protein complex, chaperone/nuclear protein complex
- 2jua.pdb.
de novo protein 16-aug-07 2jua
He Hg
(NMR, 20 structures)
Title: assignment, structure, and dynamics of de novo designed protein s836
Author: a. go, s. kim, j. s. baum, m. h. hecht
- 2jwm.pdb.
plant protein 16-oct-07 2jwm
He Hg
(NMR, 20 structures)
Title: nmr spatial srtucture of ternary complex kalata b7/mn2+/dpc micelle
Author: k. d. nadezhdin, z. o. shenkarev, l. skjeldal, a. s. arseniev
Keywords: cyctine knot, divalent cation-binding site, cytolysis, hemolysis, knottin, plant defense, plant protein
- 2jx0.pdb.
cell adhesion, signaling protein 01-nov-07 2jx0
He Hg
(NMR, 20 structures)
Title: the paxillin-binding domain (pbd) of g protein coupled receptor (gpcr)-kinase (grk) interacting protein 1 (git1)
Author: z. zhang, c. d. guibao, j. a. simmerman, j. zheng
Keywords: ank repeat, cytoplasm, gtpase activation, metal-binding, phosphorylation, zinc, zinc-finger, cell adhesion, signaling protein
- 2jxq.pdb.
ribonucleic acid 28-nov-07 2jxq
Ho
(NMR, 10 structures)
Title: nmr structure of rna duplex
Author: l. popenda, r. w. adamiak, z. gdaniec
Keywords: duplex, a-type
- 2jxs.pdb.
ribonucleic acid 29-nov-07 2jxs
Ho
(NMR, 10 structures)
Title: nmr structure of rna duplex containing single adenosine bulge
Author: l. popenda, r. w. adamiak, z. gdaniec
Keywords: duplex, bulge
- 2k2g.pdb.
hydrolase 01-apr-08 2k2g
He Hg Zn
(NMR, 17 structures)
Title: solution structure of the wild-type catalytic domain of human matrix metalloproteinase 12 (mmp-12) in complex with a tight-binding inhibitor
Author: m. a. markus, b. dwyer, s. wolfrom, j. li, w. li, k. malakian, j. wilhelm, d. h. h. tsao
Keywords: secreted, zinc, zymogen
- 2k38.pdb.
antimicrobial protein 23-apr-08 2k38
He Hg
(NMR)
Title: cupiennin 1a, nmr, minimized average structure
Author: t. l. pukala, m. p. boland, j. d. gehman, l. kuhn-nentwig, f. separovic, j. h. bowie
Keywords: membrane active, amidation, antibiotic, antimicrobial, cytolysis, hemolysis, neurotoxin, secreted, helix-hinge-helix, antimicrobial protein
- 2nq9.pdb.
hydrolase/dna 30-oct-06 2nq9
Zn
Title: high resolution crystal structure of escherichia coli endonuclease iv (endo iv) y72a mutant bound to damaged dna
Author: e. d. garcin-hosfield, d. j. hosfield, j. a. tainer
Keywords: trinuclear zn active site, hydrolase/dna complex
- 2nqh.pdb.
hydrolase 31-oct-06 2nqh
Zn
Title: high resolution crystal structure of escherichia coli endonuclease iv (endo iv) e261q mutant
Author: e. d. garcin-hosfield, d. j. hosfield, j. a. tainer
Keywords: trinuclear zinc center, hydrolase
- 2nqj.pdb.
hydrolase 31-oct-06 2nqj
Zn
Title: crystal structure of escherichia coli endonuclease iv (endo iv) e261q mutant bound to damaged dna
Author: e. d. garcin-hosfield, d. j. hosfield, j. a. tainer
Keywords: trinuclear zinc site, hydrolase
- 2nsa.pdb.
chaperone 03-nov-06 2nsa
Se
Title: structures of and interactions between domains of trigger factor from themotoga maritim
Author: e. martinez-hackert, w. a. hendrickson
- 2nsb.pdb.
chaperone 03-nov-06 2nsb
Title: structures of and interactions between domains of trigger factor from themotoga maritima
Author: e. martinez-hackert, w. a. hendrickson
- 2nsc.pdb.
chaperone 03-nov-06 2nsc
Title: structures of and interactions between domains of trigger factor from themotoga maritima
Author: e. martinez-hackert, w. a. hendrickson
- 2nui.pdb.
hydrolase 09-nov-06 2nui
Cl
Title: x-ray structure of synthetic [d83a]rnase a
Author: d. j. boerema, v. a. tereshko, s. b. h. kent
Keywords: hydrolase
- 2o8n.pdb.
protein binding 12-dec-06 2o8n
Cl Se
Title: crystal structure of mouse apolipoprotein a-i binding protein
Author: i. a. shumilin, k. n. jha, h. zheng, m. chruszcz, m. cymborowski, j. c. herr, w. minor
Keywords: protein binding
- 2omv.pdb.
cell invasion/cell adhesion 23-jan-07 2omv
Cl Ca
Title: crystal structure of inla s192n y369s/hec1 complex
Author: t. wollert, d. w. heinz, w. d. schubert
Keywords: invasion protein, ig-like domain, adhesion protein, cell invasion/cell adhesion complex
- 2omw.pdb.
cell invasion/cell adhesion 23-jan-07 2omw
Cl
Title: crystal structure of inla s192n y369s/mec1 complex
Author: t. wollert, d. w. heinz, w. d. schubert
Keywords: invasion protein, ig-like domain, adhesion protein, cell invasion/cell adhesion complex
- 2omy.pdb.
cell invasion/cell adhesion 23-jan-07 2omy
Cl Ca
Title: crystal structure of inla s192n/hec1 complex
Author: t. wollert, d. w. heinz, w. d. schubert
Keywords: invasion protein, ig-like domain, adhesion protein, cell invasion/cell adhesion complex
- 2p4z.pdb.
hydrolase 14-mar-07 2p4z
Fe
Title: a ferredoxin-like metallo-beta-lactamase superfamily protein from thermoanaerobacter tengcongensis
Author: d. -c. liang, s. -y. gu
- 2p5l.pdb.
transcription repressor 15-mar-07 2p5l
Title: crystal structure of a dimer of n-terminal domains of ahrc in complex with an 18bp dna operator site
Author: j. a. garnett, f. marincs, s. baumberg, p. g. stockley, s. e. v. phillips
Keywords: winged helix-turn-helix, arg box, protein-dna complex, transcription repressor
- 2poq.pdb.
oxidoreductase 27-apr-07 2poq
Title: dimeric dihydrodiol dehydrogenase complexed with inhibitor, isoascorbic acid
Author: v. carbone, o. el-kabbani
Keywords: predominantly anti- parallel beta sheet, oxidoreductase
- 2pq4.pdb.
chaperone/oxidoreductase 01-may-07 2pq4
He Hg
(NMR, 20 structures)
Title: nmr solution structure of napd in complex with napa1-35 signal peptide
Author: o. m. minailiuc, i. ekiel, m. milad, montreal-kingston bacterial structural genomics initiative (bsgi)
Keywords: chaperone/oxidoreductase complex
- 2prh.pdb.
oxidoreductase 04-may-07 2prh
Cl F
Title: the structures of apo- and inhibitor bound human dihydroorotate dehydrogenase reveal conformational flexibility within the inhibitor binding site
Author: b. walse, v. t. dufe, s. al-karadaghi
Keywords: oxidoreductase
- 2prl.pdb.
oxidoreductase 04-may-07 2prl
Title: the structures of apo- and inhibitor bound human dihydroorotate dehydrogenase reveal conformational flexibility within the inhibitor binding site
Author: b. walse, v. t. dufe, s. al-karadaghi
Keywords: oxidoreductase
- 2prm.pdb.
oxidoreductase 04-may-07 2prm
Title: the structures of apo- and inhibitor bound human dihydroorotate dehydrogenase reveal conformational flexibility within the inhibitor binding site
Author: b. walse, v. t. dufe, s. al-karadaghi
Keywords: oxidoreductase
- 2psn.pdb.
lyase 07-may-07 2psn
Mg
Title: crystal structure of enolase1
Author: j. k. hyo, j. k. seung, j. c. sang
Keywords: lyase
- 2puu.pdb.
transferase 09-may-07 2puu
Title: crystal structure of p38 complex with 1-(5-tert-butyl-2-p- tolyl-2h-pyrazol-3-yl)-3-[4-(6-morpholin-4-ylmethyl- pyridin-3-yl)naphthalen-1-yl]urea
Author: k. c. qian
Keywords: map kinases, crystal structure, drug discovery, transferase
- 2pyk.pdb.
hydrolase 16-may-07 2pyk
Title: crystal structure of staphylococcal nuclease variant v66q/p117g/h124l/s128a at room temperature
Author: j. l. schlessman, c. abe, e. b. garcia-moreno
Keywords: nuclease, hyperstable variant, internal waters, hydrolase
- 2pzt.pdb.
hydrolase 18-may-07 2pzt
Title: crystal structure of staphylococcal nuclease variant v66q/p117g/h124l/s128a at 100 k
Author: j. l. schlessman, c. abe, e. b. garcia-moreno
Keywords: nuclease, hyperstable variant, internal waters, hydrolase
- 2pzu.pdb.
hydrolase 18-may-07 2pzu
Title: crystal structure of staphylococcal nuclease variant v66n/p117g/h124l/s128a at cryogenic temperature
Author: j. l. schlessman, c. abe, e. b. garcia-moreno
Keywords: nuclease, hyperstable variant, internal waters, hydrolase
- 2pzw.pdb.
hydrolase 18-may-07 2pzw
Title: crystal structure of staphylococcal nuclease variant v66n/p117g/h124l/s128a at room temperature
Author: j. l. schlessman, c. abe, e. b. garcia-moreno
Keywords: nuclease, hyperstable variant, internal waters, hydrolase
- 2q7t.pdb.
hydrolase 07-jun-07 2q7t
Mg
Title: crystal structure of the f plasmid trai relaxase domain with the scissile thymidine base
Author: s. a. lujan, m. r. redinbo
Keywords: hydrolase, conjugation
- 2q7u.pdb.
hydrolase 07-jun-07 2q7u
Mg
Title: crystal structure of the f plasmid trai relaxase domain with the scissile thymidine base and imidodiphosphate
Author: s. a. lujan, m. r. redinbo
Keywords: hydrolase, conjugation, alternative initiation, atp-binding, dna-binding, helicase, nucleotide-binding, plasmid
- 2q8x.pdb.
hydrolase 12-jun-07 2q8x
Na
Title: the high-resolution crystal structure of ixt6, a thermophilic, intracellular xylanase from g. stearothermophilus
Author: v. solomon, a. teplitsky, r. gilboa, g. zolotnitsky, g. golan, v. reiland, s. moryles, y. shoham, g. shoham
- 2qfn.pdb.
transport protein 27-jun-07 2qfn
Fe
Title: x-ray crystal structure analysis of the binding site in the ferric and oxyferrous forms of the recombinant heme dehaloperoxidase cloned from amphitrite ornata
Author: v. de serrano, z. chen, m. f. davis, s. franzen
Keywords: dhp, globin, heme protein, transport protein
- 2qha.pdb.
hydrolase 01-jul-07 2qha
Zn
Title: from structure to function: insights into the catalytic substrate specificity and thermostability displayed by bacillus subtilis mannanase bcman
Author: x. x. yan, d. c. liang
Keywords: his1-his23-glu336 metal-binding motif, disulfide bond, shallow-dish-shaped active center, hydrolase
- 2qhy.pdb.
hydrolase 03-jul-07 2qhy
F
Title: crystal structure of protease inhibitor, mit-1-ac86 in complex with wild type hiv-1 protease
Author: c. a. schiffer, m. n. l. nalam
Keywords: hiv-1 protease, protease inhibitors, hydrolase
- 2qhz.pdb.
hydrolase 03-jul-07 2qhz
F
Title: crystal structure of protease inhibitor, mit-1-ac87 in complex with wild type hiv-1 protease
Author: c. a. schiffer, m. n. l. nalam
Keywords: hiv-1 protease, protease inhibitors, hydrolase
- 2qi0.pdb.
hydrolase 03-jul-07 2qi0
F
Title: crystal structure of protease inhibitor, mit-1-kk80 in complex with wild type hiv-1 protease
Author: c. a. schiffer, m. n. l. nalam
Keywords: hiv-1 protease, protease inhibitors, hydrolase
- 2qi1.pdb.
hydrolase 03-jul-07 2qi1
Title: crystal structure of protease inhibitor, mit-1-kk81 in complex with wild type hiv-1 protease
Author: c. a. schiffer, m. n. l. nalam
Keywords: hiv-1 protease, protease inhibitors, hydrolase
- 2qi3.pdb.
hydrolase 03-jul-07 2qi3
Title: crystal structure of protease inhibitor, mit-2-ad94 in complex with wild type hiv-1 protease
Author: m. n. l nalam, c. a. schiffer
Keywords: hiv-1 protease, protease inhibitors, hydrolase
- 2qi4.pdb.
hydrolase 03-jul-07 2qi4
Title: crystal structure of protease inhibitor, mit-2-ad93 in complex with wild type hiv-1 protease
Author: m. n. l. nalam, c. a. schiffer
Keywords: hiv-1 protease, protease inhibitors, hydrolase
- 2qi5.pdb.
hydrolase 03-jul-07 2qi5
Title: crystal structure of protease inhibitor, mit-2-kc08 in complex with wild type hiv-1 protease
Author: c. a. schiffer, m. n. l. nalam
Keywords: hiv-1 protease, protease inhibitors, hydrolase
- 2qi6.pdb.
hydrolase 03-jul-07 2qi6
Title: crystal structure of protease inhibitor, mit-2-kb98 in complex with wild type hiv-1 protease
Author: c. a. schiffer, m. n. l. nalam
Keywords: hiv-1 protease, protease inhibitors, hydrolase
- 2qi7.pdb.
hydrolase 03-jul-07 2qi7
Title: crystal structure of protease inhibitor, mit-2-ad86 in complex with wild type hiv-1 protease
Author: c. a. schiffer, m. n. l. nalam
Keywords: hiv-1 protease, protease inhibitors, hydrolase
- 2qih.pdb.
cell adhesion 04-jul-07 2qih
Cl
Title: crystal structure of 527-665 fragment of uspa1 protein from moraxella catarrhalis
Author: r. conners, r. l. brady
Keywords: cell adhesion
- 2qj5.pdb.
signaling protein 06-jul-07 2qj5
Title: pyp ultra-high resolution of a bacterial photoreceptor
Author: p. d. coureux, z. p. fan, v. stojanoff, u. k. genick
Keywords: signaling protein
- 2qj7.pdb.
signaling protein 06-jul-07 2qj7
Title: pyp ultra-high resolution of a bacterial photoreceptor
Author: p. d. coureux, z. p. fan, v. stojanoff, u. k. genick
Keywords: pas domain, signal transduction, signaling protein
- 2qr5.pdb.
hydrolase 27-jul-07 2qr5
Title: aeropyrum pernix acylaminoacyl peptidase, h367a mutant
Author: v. harmat, a. pallo, a. l. kiss, l. polgar
Keywords: thermophilic enzyme, oxyanion binding site, catalytic activity, hydrolase
- 2qyp.pdb.
lipid binding protein 15-aug-07 2qyp
Title: orthorhombic crystal structure of human saposin c dimer in open conformation
Author: m. rossmann, w. saenger, t. maier
Keywords: lipid binding protein
- 2r0f.pdb.
sugar binding protein 19-aug-07 2r0f
Title: ligand free structure of fungal lectin cgl3
Author: m. a. waelti, p. j. walser, s. thore, a. gruenler, n. ban, m. kuenzler, m. aebi
Keywords: lectin, sugar binding protein, chitooligosaccharides
- 2r0h.pdb.
sugar binding protein 20-aug-07 2r0h
Title: fungal lectin cgl3 in complex with chitotriose (chitotetraose)
Author: m. a. waelti, p. j. walser, s. thore, a. gruenler, n. ban, m. kuenzler, m. aebi
Keywords: lectin, sugar binding protein, chitotriose, chitooligosaccharides
- 2r0r.pdb.
lipid binding protein 21-aug-07 2r0r
Title: crystal structure of human saposin d variant sapd k9e
Author: m. rossmann, w. saenger, t. maier
Keywords: sphingolipid metabolism
- 2r1q.pdb.
lipid binding protein 23-aug-07 2r1q
I
Title: crystal structure of iodinated human saposin d in space group c2221
Author: t. maier, m. rossman, w. saenger
Keywords: sphingolipid metabolism
- 2r2y.pdb.
protein binding 28-aug-07 2r2y
Title: crystal structure of the proteasomal rpn 13 pru-domain
Author: m. groll, k. walters, i. dikic, d. finley
Keywords: ubiquitin, ph-domain, 19s regulator, receptor, ubiquitin-proteasome-degradation pathway, receptor domain for ubiquitin and proteasome binding, protein binding
- 2rb3.pdb.
lipid binding protein 18-sep-07 2rb3
Title: crystal structure of human saposin d
Author: t. maier, m. rossman, w. saenger
Keywords: sphingolipid metabolism
- 2rgj.pdb.
oxidoreductase 03-oct-07 2rgj
Se
Title: crystal structure of flavin-containing monooxygenase phzs
Author: j. e. ladner, j. f. parsons, b. t. greenhagen, h. robinson
Keywords: flavin, fad, phenazine, pyocyanin, pseudomonas, oxidoreductase
- 2rkx.pdb.
lyase 18-oct-07 2rkx
Title: the 3d structure of chain d, cyclase subunit of imidazoleglycerol_evolvedcerolphosphate synthase
Author: d. tawfik, o. khersonsky, s. albeck, o. dym, israel structural proteomics center (ispc)
Keywords: structural genomics, israel structural proteomics center, ispc, amino-acid biosynthesis, cytoplasm, histidine biosynthesis, lyase
- 2ro1.pdb.
transcription 04-mar-08 2ro1
He Hg Zn
(NMR, 20 structures)
Title: nmr solution structures of human kap1 phd finger-bromodomain
Author: l. zeng, k. l. yap, a. v. ivanov, x. wang, s. mujtaba, o. plotnikova, f. j. rauscher
Keywords: tif, phd finger, bromodomain, sumo, acetylation, alternative splicing, metal-binding, nucleus, phosphoprotein, repressor, transcription, transcription regulation, zinc, zinc-finger
- 2uvx.pdb.
transferase/inhibitor complex 15-mar-07 2uvx
Title: structure of pka-pkb chimera complexed with 7-azaindole
Author: t. g. davies, a. donald, t. mchardy, m. g. rowlands, l. j. hunter, r. g. boyle, g. w. aherne, m. d. garrett, i. collins
Keywords: phosphorylation
- 2uvy.pdb.
transferase/inhibitor complex 15-mar-07 2uvy
Title: structure of pka-pkb chimera complexed with methyl-(4-(9h- purin-6-yl)-benzyl)-amine
Author: t. g. davies, a. donald, t. mchardy, m. g. rowlands, l. j. hunter, r. g. boyle, g. w. aherne, m. d. garrett, i. collins
Keywords: kinase, myristate, transferase, lipoprotein, serine/threonine-protein kinase, nucleotide-binding, protein kinase inhibitor, atp-binding, nuclear protein, phosphorylation, transferase/inhibitor comple...
- 2uvz.pdb.
transferase/inhibitor complex 15-mar-07 2uvz
Title: structure of pka-pkb chimera complexed with c-phenyl-c-(4-( 9h-purin-6-yl)-phenyl)-methylamine
Author: t. g. davies, a. donald, t. mchardy, m. g. rowlands, l. j. hunter, r. g. boyle, g. w. aherne, m. d. garrett, i. collins
Keywords: kinase, myristate, transferase, lipoprotein, serine/threonine-protein kinase, nucleotide-binding, protein kinase inhibitor, atp-binding, nuclear protein, phosphorylation, transferase/inhibitor comple...
- 2uw0.pdb.
transferase/inhibitor complex 15-mar-07 2uw0
Cl
Title: structure of pka-pkb chimera complexed with 6-(4-(4-(4- chloro-phenyl)-piperidin-4-yl)-phenyl)-9h-purine
Author: t. g. davies, a. donald, t. mchardy, m. g. rowlands, l. j. hunter, r. g. boyle, g. w. aherne, m. d. garrett, i. collins
Keywords: kinase, myristate, transferase, lipoprotein, serine/threonine-protein kinase, nucleotide-binding, protein kinase inhibitor, atp-binding, nuclear protein, phosphorylation, transferase/inhibitor comple...
- 2uxz.pdb.
hydrolase 02-apr-07 2uxz
Br
Title: two-carbon-elongated hiv-1 protease inhibitors with a tertiary-alcohol-containing transition-state mimic
Author: n. ginman, b. samuelsson, a. hallberg, j. t. unge, t. k. unge
Keywords: protease, hydrolase, inhibitor, aspartyl protease
- 2uy0.pdb.
hydrolase 02-apr-07 2uy0
Br
Title: two-carbon-elongated hiv-1 protease inhibitors with a tertiary-alcohol-containing transition-state mimic
Author: n. ginman, b. samuelsson, a. hallberg, j. t. unge, t. k. unge
Keywords: protease, hydrolase, inhibitor, aspartyl protease
- 2uz8.pdb.
rna-binding protein 26-apr-07 2uz8
Se
Title: the crystal structure of p18, human translation elongation factor 1 epsilon 1
Author: b. s. kang, k. j. kim, m. h. kim, t. k. oh, s. kim
Keywords: aminoacyl-trna synthetase, p18, gst, nuclear protein, elongation factor, rna-binding protein
- 2uza.pdb.
oxidoreductase 27-apr-07 2uza
Mg Fe Ca
Title: crystal structure of the free radical intermediate of pyruvate:ferredoxin oxidoreductase from desulfovibrio africanus
Author: e. chabriere, c. cavazza, c. contreras-martel, j. c. fontecilla-camps
Keywords: 4fe-4s, pyruvate, transport, iron-sulfur, tpp-dependent enzyme, iron-sulfur cluster, pyruvate catabolism, metal-binding, oxidoreductase, electron transport
- 2v2q.pdb.
transferase 06-jun-07 2v2q
Br
Title: ispe in complex with ligand
Author: m. s. alphey, w. n. hunter
Keywords: 4-diphosphocytidyl-2c-methyl-d-erythritol, aquifex aeolicus, nucleotide-binding, isoprene biosynthesis, kinase, transferase, atp-binding, non-mevalonate
- 2v2v.pdb.
transferase 07-jun-07 2v2v
Br
Title: ispe in complex with ligand
Author: m. s. alphey, w. n. hunter
Keywords: 4-diphosphocytidyl-2c-methyl-d- erythritol, aquifex aeolicus, nucleotide-binding, isoprene biosynthesis, kinase, transferase, atp-binding, non-mevalonate
- 2v5l.pdb.
oxidoreductase 06-jul-07 2v5l
Title: structures of the open and closed state of trypanosomal triosephosphate isomerase: as observed in a new crystal form: implications for the reaction mechanism
Author: m. e. m. noble, j. p. zeelen, r. k. wierenga
Keywords: pentose shunt, gluconeogenesis, binding studies, tim, isomerase, glycosome, glycolysis, engineering, lipid synthesis, fatty acid biosynthesis, oxidoreductase
- 2v6x.pdb.
protein transport 23-jul-07 2v6x
Se
Title: stractural insight into the interaction between escrt-iii and vps4
Author: t. obita, o. perisic, s. ghazi-tabatabai, s. saksena, s. d. emr, r. l. williams
Keywords: vacuolar protein sorting
- 2vbe.pdb.
viral protein 12-sep-07 2vbe
Mn Ca Se
Title: tailspike protein of bacteriophage sf6
Author: s. barbirz, j. j. mueller, a. freiberg, u. heinemann, r. seckler
Keywords: tailspike, viral protein, oligomeric right-handed parallel beta-helix
- 2vbk.pdb.
viral protein 14-sep-07 2vbk
Mg
Title: native tailspike protein of bacteriophage sf6
Author: j. j. mueller, s. barbirz, k. heinle, a. freiberg, r. seckler, u. heinemann
Keywords: viral protein, hydrolase, tailspike, endorhamnosidase, right-handed parallel beta-helix
- 2vbm.pdb.
viral protein 14-sep-07 2vbm
Mg Mn
Title: tailspike protein of bacteriophage sf6 complexed with tetrasaccharide
Author: j. j. mueller, s. barbirz, a. freiberg, r. seckler, u. heinemann
Keywords: viral protein, hydrolase, tailspike, endorhamnosidase, right-handed parallel beta-helix
- 2vd8.pdb.
isomerase 01-oct-07 2vd8
Cl Mg
Title: the crystal structure of alanine racemase from bacillus anthracis (ba0252)
Author: k. au, j. ren, t. s. walter, k. harlos, j. e. nettleship, r. j. owens, d. i. stuart, r. m. esnouf, oxford protein production facility (oppf), structural proteomics in europe (spine)
Keywords: structural proteomics in europe (spine)
- 2vd9.pdb.
isomerase 01-oct-07 2vd9
Cl Mg
Title: the crystal structure of alanine racemase from bacillus anthracis (ba0252) with bound l-ala-p
Author: k. au, j. ren, t. s. walter, k. harlos, j. e. nettleship, r. j. owens, d. i. stuart, r. m. esnouf, oxford protein production facility (oppf), structural proteomics in europe (spine)
Keywords: structural proteomics in europe (spine)
- 2vef.pdb.
transferase 24-oct-07 2vef
Title: dihydropteroate synthase from streptococcus pneumoniae
Author: j. p. derrick, c. levy
Keywords: folic acid, transferase, biosynthesis, streptococcus, dihydropteroate, folate biosynthesis
- 2vhs.pdb.
hydrolase 24-nov-07 2vhs
Title: cathsilicatein, a chimera
Author: m. fairhead, t. kowatz, s. a. mcmahon, l. g. carter, m. oke, k. a. johnson, h. liu, j. h. naismith, c. f. v. d. wal
Keywords: protease, lysosome, hydrolase, glycoprotein, thiol protease, silica condensation
- 2vi7.pdb.
transferase 28-nov-07 2vi7
Title: structure of a putative acetyltransferase (pa1377)from pseudomonas aeruginosa
Author: a. m. davies, r. tata, f. x. chauviac, b. j. sutton, p. r. brown
Keywords: gcn5 family, transferase, n-acetyltransferase, hypothetical protein, pseudomonas aeruginosa
- 2vln.pdb.
protein-binding 15-jan-08 2vln
Title: n75a mutant of e9 dnase domain in complex with im9
Author: a. h. keeble, l. a. joachimiak, m. j. mate, n. meenan, n. kirkpatrick, d. baker, c. kleanthous
Keywords: metal-binding, antimicrobial, bacteriocin immunity, hydrolase, antibiotic, bacteriocin, endonuclease, zinc, colicin, plasmid, nuclease, hth motif, protein-binding
- 2vlo.pdb.
protein-binding 15-jan-08 2vlo
Title: k97a mutant of e9 dnase domain in complex with im9
Author: a. h. keeble, l. a. joachimiak, m. j. mate, n. meenan, n. kirkpatrick, d. baker, c. kleanthous
Keywords: metal-binding, antimicrobial, bacteriocin immunity, hydrolase, antibiotic, bacteriocin, endonuclease, zinc, colicin, plasmid, nuclease, hth motif, protein-binding
- 2vlp.pdb.
protein-binding 15-jan-08 2vlp
Title: r54a mutant of e9 dnase domain in complex with im9
Author: a. h. keeble, l. a. joachimiak, m. j. mate, n. meenan, n. kirkpatrick, d. baker, c. kleanthous
Keywords: metal-binding, antimicrobial, bacteriocin immunity, hydrolase, antibiotic, bacteriocin, endonuclease, zinc, colicin, plasmid, nuclease, hth motif, protein-binding
- 2vlq.pdb.
protein-binding 15-jan-08 2vlq
Title: f86a mutant of e9 dnase domain in complex with im9
Author: a. h. keeble, l. a. joachimiak, m. j. mate, n. meenan, n. kirkpatrick, d. baker, c. kleanthous
Keywords: metal-binding, antimicrobial, bacteriocin immunity, hydrolase, antibiotic, bacteriocin, endonuclease, zinc, colicin, plasmid, nuclease, hth motif, protein-binding
- 2vn1.pdb.
isomerase 30-jan-08 2vn1
Title: crystal structure of the fk506-binding domain of plasmodium falciparum fkbp35 in complex with fk506
Author: m. kotaka, r. alag, h. ye, p. r. preiser, h. s. yoon, j. lescar
Keywords: fk506, isomerase, tpr repeat, plasmodium falciparum
- 2vn4.pdb.
hydrolase 30-jan-08 2vn4
Title: glycoside hydrolase family 15 glucoamylase from hypocrea jecorina
Author: r. bott, m. sandgren, h. hansson
Keywords: glycoside hydrolase family 15, glucoamylase, amyloglucosidase, hypocrea jecorina
- 2vn5.pdb.
cell adhesion 31-jan-08 2vn5
Ca
Title: the clostridium cellulolyticum dockerin displays a dual binding mode for its cohesin partner
Author: b. a. pinheiro, j. a. m. prates, m. r. proctor, h. j. gilbert, g. j. davies, v. a. money, c. martinez-fleites, e. a. bayer, c. m. g. a. fontes, h. p. fierobe
Keywords: polysaccharide degradation, cohesin, dockerin, hydrolase, cellulosome, glycosidase, cellulose degradation, cell adhesion
- 2vn7.pdb.
hydrolase 31-jan-08 2vn7
Ca
Title: glycoside hydrolase family 15 glucoamylase from hypocrea jecorina
Author: r. bott, m. sandgren, h. hansson
Keywords: glycoside hydrolase family 15, hypocrea jecorina, hydrolase
- 2vnm.pdb.
hydrolase 05-feb-08 2vnm
F
Title: human bace-1 in complex with 3-(1,1-dioxidotetrahydro-2h-1, 2-thiazin-2-yl)-5-(ethylamino)-n-((1s,2r)-2-hydroxy-1-( phenylmethyl)-3-(((3-(trifluoromethyl)phenyl)methyl)amino) propyl)benzamide
Author: n. charrier, b. clarke, l. cutler, e. demont, c. dingwall, r. dunsdon, p. east, j. hawkins, c. howes, i. hussain, p. jeffrey, g. maile, r. matico, j. mosley, a. naylor, a. obrien, s. redshaw, p. rowland, v. soleil, k. j. smith, s. sweitzer, p. theobald, d. vesey, d. s. walter, g. wayne
Keywords: beta-site app cleaving enzyme, beta-secretase, aspartyl protease, asp-2, bace-1, zymogen, protease, membrane, hydrolase, memapsin-2, glycoprotein, transmembrane
- 2vnn.pdb.
hydrolase 05-feb-08 2vnn
F
Title: human bace-1 in complex with 7-ethyl-n-((1s,2r)-2-hydroxy-1- (phenylmethyl)-3-(((3-(trifluoromethyl)phenyl)methyl)amino) propyl)-1-methyl-3,4-dihydro-1h-(1,2,5)thiadiazepino(3,4,5- hi)indole-9-carboxamide 2,2-dioxide
Author: n. charrier, b. clarke, l. cutler, e. demont, c. dingwall, r. dunsdon, p. east, j. hawkins, c. howes, i. hussain, p. jeffrey, g. maile, r. matico, j. mosley, a. naylor, a. obrien, s. redshaw, p. rowland, v. soleil, k. j. smith, s. sweitzer, p. theobald, d. vesey, d. s. walter, g. wayne
Keywords: beta-site app cleaving enzyme, beta-secretase, aspartyl protease, asp-2, bace-1, zymogen, protease, membrane, hydrolase, memapsin-2, glycoprotein, transmembrane
- 2vof.pdb.
apoptosis 17-feb-08 2vof
Cl Se
Title: structure of mouse a1 bound to the puma bh3-domain
Author: c. smits, p. e. czabotar, m. g. hinds, c. l. day
Keywords: bcl-2, cytoplasm, apoptosis, pro-survival, mitochondrion, protein-protein complex
- 2vog.pdb.
apoptosis 17-feb-08 2vog
Cl
Title: structure of mouse a1 bound to the bmf bh3-domain
Author: c. smits, p. e. czabotar, m. g. hinds, c. l. day
Keywords: bh3, bcl-2, cytoplasm, apoptosis, pro-survival
- 2voh.pdb.
apoptosis 17-feb-08 2voh
Title: structure of mouse a1 bound to the bak bh3-domain
Author: c. smits, p. e. czabotar, m. g. hinds, c. l. day
Keywords: bcl-2, membrane, cytoplasm, apoptosis, pro-survival, transmembrane, protein-protein complex
- 2voi.pdb.
apoptosis 17-feb-08 2voi
Cl
Title: structure of mouse a1 bound to the bid bh3-domain
Author: c. smits, p. e. czabotar, m. g. hinds, c. l. day
Keywords: bh3, bcl-2, membrane, apoptosis, cytoplasm, pro-survival, mitochondrion, phosphoprotein
- 2vou.pdb.
oxidoreductase 21-feb-08 2vou
Title: structure of 2,6-dihydroxypyridine-3-hydroxylase from arthrobacter nicotinovorans
Author: n. treiber, g. e. schulz
Keywords: aromatic hydroxylase, nicotine degradation, flavin mono-oxygenase, fad-dependent hydroxylase, oxidoreductase
- 2vov.pdb.
metal-binding protein 22-feb-08 2vov
Cu Ca
Title: an oxidized tryptophan facilitates copper-binding in methylococcus capsulatus secreted protein mope. the stucture of wild-type mope to 1.35aa
Author: r. helland, a. fjellbirkeland, o. a. karlsen, t. ve, j. r. lillehaug, h. b. jensen
Keywords: metal-binding protein, oxidized tryptophan, methanotroph bacterium, kunurenine, copper binding, copper homeostasis
- 2vow.pdb.
metal-binding protein 22-feb-08 2vow
Ca
Title: an oxidized tryptophan facilitates copper-binding in methylococcus capsulatus secreted protein mope. the stucture of recombinant mope to 1.65aa
Author: r. helland, a. fjellbirkeland, o. a. karlsen, t. ve, j. r. lillehaug, h. b. jensen
Keywords: metal-binding protein, oxidized tryptophan, methanotroph bacterium, kunurenine, copper binding, copper homeostasis
- 2vox.pdb.
metal-binding protein 22-feb-08 2vox
Hg Cu Ca
Title: an oxidized tryptophan facilitates copper-binding in methylococcus capsulatus secreted protein mope. the stucture of mercury soaked mope to 1.9aa
Author: r. helland, a. fjellbirkeland, o. a. karlsen, t. ve, j. r. lillehaug, h. b. jensen
Keywords: metal-binding protein, oxidized tryptophan, methanotroph bacterium, kunurenine, copper binding, copper homeostasis
- 2vqe.pdb.
ribosome 13-mar-08 2vqe
Mg K Zn
Title: modified uridines with c5-methylene substituents at the first position of the trna anticodon stabilize u-g wobble pairing during decoding
Author: s. kurata, a. weixlbaumer, t. ohtsuki, t. shimazaki, t. wada, y. kirino, k. takai, k. watanabe, v. ramakrishnan, t. suzuki
Keywords: rrna-binding, metal-binding, zinc-finger, translation, coiled coil, paromomycin, trna, zinc, mrna, cmo5u, ribosome, rna-binding, modifiactions, ribosomal protein, ribonucleoprotein
- 2vqf.pdb.
ribosome 14-mar-08 2vqf
Mg K Zn
Title: modified uridines with c5-methylene substituents at the first position of the trna anticodon stabilize u-g wobble pairing during decoding
Author: s. kurata, a. weixlbaumer, t. ohtsuki, t. shimazaki, t. wada, y. kirino, k. takai, k. watanabe, v. ramakrishnan, t. suzuki
Keywords: rrna-binding, metal-binding, zinc-finger, translation, coiled coil, paromomycin, trna, zinc, mrna, cmo5u, ribosome, rna-binding, modifiactions, ribosomal protein, ribonucleoprotein
- 2vqg.pdb.
membrane protein 15-mar-08 2vqg
Zn As
Title: crystal structure of porb from corynebacterium glutamicum ( crystal form i)
Author: k. ziegler, r. benz, g. e. schulz
Keywords: membrane protein, porin, membrane, transport, ion transport
- 2vqh.pdb.
membrane protein 15-mar-08 2vqh
Zn As
Title: crystal structure of porb from corynebacterium glutamicum ( crystal form ii)
Author: k. ziegler, r. benz, g. e. schulz
Keywords: membrane protein, porin, membrane, transport, ion transport
- 2vqk.pdb.
membrane protein 17-mar-08 2vqk
Zn As
Title: crystal structure of porb from corynebacterium glutamicum ( crystal form iv)
Author: k. ziegler, r. benz, g. e. schulz
Keywords: membrane protein, porin, membrane, transport, ion transport
- 2vql.pdb.
membrane protein 17-mar-08 2vql
Zn As
Title: crystal structure of porb from corynebacterium glutamicum ( crystal form iii)
Author: k. ziegler, r. benz, g. e. schulz
Keywords: membrane protein, porin, membrane, transport, ion transport
- 2vsk.pdb.
hydrolase 24-apr-08 2vsk
Title: hendra virus attachment glycoprotein in complex with human cell surface receptor ephrinb2
Author: t. a. bowden, a. r. aricescu, r. j. gilbert, j. m. grimes, e. y. jones, d. i. stuart
Keywords: niv-g, phosphoprotein, differentiation, viral attachment, signal-anchor, hemagglutinin, transmembrane
- 2vsm.pdb.
hydrolase 25-apr-08 2vsm
Title: nipah virus attachment glycoprotein in complex with human cell surface receptor ephrinb2
Author: t. a. bowden, a. r. aricescu, r. j. gilbert, j. m. grimes, e. y. jones, d. i. stuart
Keywords: niv-g, phosphoprotein, differentiation, viral attachment, signal-anchor, hemagglutinin, transmembrane
- 2vt1.pdb.
membrane protein 08-may-08 2vt1
Title: crystal structure of the cytoplasmic domain of spa40, the specificity switch for the shigella flexneri type iii secretion system
Author: j. e. deane, s. c. graham, e. p. mitchell, d. flot, s. johnson, s. m. lea
Keywords: specificity switch, virulence, transmembrane, inner membrane, flhb, yscu, t3ss, spa40, plasmid, membrane, type iii secretion system, membrane protein
- 2vt8.pdb.
hydrolase inhibitor 12-may-08 2vt8
Title: structure of a conserved dimerisation domain within fbox7 and pi31
Author: r. j. kirk, j. murray-rust, p. p. knowles, h. laman, n. q. mcdonald
Keywords: polymorphism, proteasome inhibitor, hydrolase inhibitor
- 2z16.pdb.
viral protein 08-may-07 2z16
Title: crystal structure of matrix protein 1 from influenza a virus a/crow/kyoto/t1/2004(h5n1)
Author: s. saijo, s. kishishita, t. uchikubo-kamo, t. terada, m. shirouzu, h. ito, t. ito, s. yokoyama, riken structural genomics/proteomics initiative (rsgi)
Keywords: m1, influenza a virus, h5n1, structural genomics, nppsfa, national project on protein structural and functional analyses, riken structural genomics/proteomics initiative, rsgi, viral protein
- 2z2c.pdb.
transferase 17-may-07 2z2c
Title: mura inhibited by unag-cnicin adduct
Author: a. steinbach, t. skarzynski, a. j. scheidig, c. d. klein
Keywords: transferase, udp-n-acetylglucosamine, cnicin
- 2z4d.pdb.
nuclear protein 15-jun-07 2z4d
He Hg
(NMR, 8 structures)
Title: nmr structures of yeast proteasome component rpn13
Author: n. zhang, k. j. walters
Keywords: nmr, ph domain, nuclear protein
- 2z59.pdb.
protein transport 01-jul-07 2z59
He Hg
(NMR, 10 structures)
Title: complex structures of mouse rpn13 (22-130aa) and ubiquitin
Author: x. chen, p. schreiner, m. groll, k. j. walters
Keywords: nmr, ph domain, protein transport
- 2z5a.pdb.
toxin 02-jul-07 2z5a
Title: ha3 subcomponent of botulinum type c progenitor toxin
Author: t. nakamura, t. tonozuka, m. kotani, k. oguma, a. nishikawa
Keywords: hemagglutinin, botulinum toxin
- 2z73.pdb.
membrane protein 13-aug-07 2z73
Title: crystal structure of squid rhodopsin
Author: m. murakami, t. kouyama
Keywords: transmembrane, vision, membrane protein
- 2z9a.pdb.
lipid binding protein 18-sep-07 2z9a
Title: crystal structure of human saposin c dimer in open conformation
Author: m. rossmann, w. saenger, t. maier
Keywords: sphingolipid metabolism
- 2za4.pdb.
hydrolase/hydrolase inhibitor 01-oct-07 2za4
Cl
Title: crystal structural analysis of barnase-barstar complex
Author: y. urakubo, t. ikura, n. ito
Keywords: endonuclease, genetically modified food, hydrolase, nuclease, secreted, cytoplasm, hydrolase/hydrolase inhibitor complex
- 2zew.pdb.
hydrolase 18-dec-07 2zew
Ca
Title: family 16 cabohydrate binding domain module 1
Author: b. bae, s. k. nair
Keywords: glycosidase, hydrolase
- 2zex.pdb.
hydrolase 18-dec-07 2zex
Ca
Title: family 16 carbohydrate binding module
Author: b. bae, s. k. nair
Keywords: glycosidase, hydrolase
- 2zey.pdb.
hydrolase 18-dec-07 2zey
Ca
Title: family 16 carbohydrate binding module
Author: s. k. nair, b. bae
Keywords: glycosidase, hydrolase
- 2zez.pdb.
hydrolase 18-dec-07 2zez
Ca
Title: family 16 carbohydrate binding module-2
Author: b. bae, s. k. nair
Keywords: glycosidase, hydrolase
- 2zfh.pdb.
structural genomics, unknown function 07-jan-08 2zfh
Title: crystal structure of putative cuta1 from homo sapiens at 2.05a resolution
Author: b. bagautdinov, k. yutani, riken structural genomics/proteomics initiative (rsgi)
Keywords: alternative splicing, structural genomics, unknown function
- 2zhx.pdb.
hydrolase/hydrolase inhibitor 11-feb-08 2zhx
Title: crystal structure of uracil-dna glycosylase from mycobacterium tuberculosis in complex with a proteinaceous inhibitor
Author: p. s. kaushal, r. k. talawar, p. d. v. krishna, u. varshney, m. vijayan
Keywords: ung-ugi complex, ung-dna interactions, cytoplasm, dna damage, glycosidase, hydrolase, hydrolase/hydrolase inhibitor complex
- 2zi3.pdb.
transferase 13-feb-08 2zi3
Title: c4s-e247a dck variant of dck in complex with d-da+adp
Author: e. sabini, a. lavie
Keywords: purine, deoxyadenosine, deoxycytidine kinase, nucleoside, enantiomer, d-da, atp-binding, nucleotide- binding, nucleus, phosphoprotein, transferase
- 2zi4.pdb.
transferase 13-feb-08 2zi4
Mg
Title: c4s dck variant of dck in complex with l-da+adp
Author: e. sabini, a. lavie
Keywords: purine, deoxyadenosine, deoxycytidine kinase, nucleoside, enantiomer, l-da, atp-binding, nucleotide- binding, nucleus, phosphoprotein, transferase
- 2zi5.pdb.
transferase 13-feb-08 2zi5
Title: c4s dck variant of dck in complex with l-da+udp
Author: e. sabini, a. lavie
Keywords: purine, deoxyadenosine, deoxycytidine kinase, nucleoside, enantiomer, l-da, udp, atp-binding, nucleotide- binding, nucleus, phosphoprotein, transferase
- 2zi6.pdb.
transferase 13-feb-08 2zi6
Title: c4s dck variant of dck in complex with d-da+udp
Author: e. sabini, a. lavie
Keywords: purine, deoxyadenosine, deoxycytidine kinase, nucleoside, enantiomer, d-da, udp, atp-binding, nucleotide- binding, nucleus, phosphoprotein, transferase
- 3b2r.pdb.
hydrolase 19-oct-07 3b2r
Title: crystal structure of pde5a1 catalytic domain in complex with vardenafil
Author: w. huanchen, y. mengchun, r. howard, h. f. sharron, k. hengming
Keywords: allosteric enzyme, alternative splicing, cgmp-binding, hydrolase, magnesium, metal-binding, nucleotide-binding, phosphorylation, polymorphism, zinc
- 3bm4.pdb.
hydrolase 12-dec-07 3bm4
Mg
Title: crystal structure of human adp-ribose pyrophosphatase nudt5 in complex with magnesium and ampcpr
Author: m. zha, q. guo, y. zhang, c. zhong, y. ou, j. ding
Keywords: adpr, adp-ribose pyrophosphatase, nudt5, molecular mechanism, substrate specificity, hydrolase, magnesium, phosphoprotein, polymorphism
- 3bok.pdb.
toxin 17-dec-07 3bok
Title: structure of the c. botulinum neurotoxin serotype a apo- enzyme
Author: n. r. silvaggi, k. n. allen
Keywords: neurotoxin, metalloprotease
- 3bon.pdb.
toxin 17-dec-07 3bon
Zn
Title: structure of the c. botulinum neurotoxin serotype a with zn2+ cofactor bound
Author: n. r. silvaggi, k. n. allen
Keywords: neurotoxin, metalloprotease
- 3boo.pdb.
toxin/toxin inhibitor 17-dec-07 3boo
Zn
Title: structure of the c. botulinum neurotoxin serotype a with an inhibitory peptide bound
Author: n. r. silvaggi, k. n. allen
Keywords: neurotoxin, metalloprotease, peptidic inhibitor, toxin/toxin inhibitor complex
- 3bpv.pdb.
transcription regulator 19-dec-07 3bpv
Title: crystal structure of marr
Author: v. saridakis, d. shahinas, x. xu, d. christendat
Keywords: dna binding, transcription factor, winged helix motif, dna-binding, transcription regulation, transcription regulator
- 3bpx.pdb.
transcription regulator 19-dec-07 3bpx
Na
Title: crystal structure of marr
Author: v. saridakis, d. shahinas, x. xu, d. christendat
Keywords: transcription factor, winged helix motif, dna binding, dna-binding, transcription regulation, transcription regulator
- 3bqp.pdb.
lipid binding protein 20-dec-07 3bqp
Mg
Title: crystal structure of human saposin d (orthorhombic)
Author: g. g. prive, k. popovic
Keywords: sphingolipid activator protein, lipid binding protein, acid ceramidase,farber disease, lipid metabolism, lysosome, sphingolipid metabolism
- 3bqq.pdb.
lipid binding protein 20-dec-07 3bqq
Title: crystal structure of human saposin d (triclinic)
Author: g. g. prive, k. popovic
Keywords: sphingolipid activator protein, lipid binding protein, acid ceramidase,farber disease, lipid metabolism, lysosome, sphingolipid metabolism
- 3brk.pdb.
transferase 21-dec-07 3brk
Se
Title: crystal structure of adp-glucose pyrophosphorylase from agrobacterium tumefaciens
Author: j. cupp-vickery, c. meyer, r. igarashi
Keywords: agrobacterium tumefaciens, allostery, kinetics, structure-function relationships, site- directed mutagenesis, glycogen biosynthesis, nucleotidyltransferase, transferase
- 3brm.pdb.
hydrolase 21-dec-07 3brm
Se
Title: crystal structure of the covalent complex between the bacillus subtilis glutaminase ybgj and 5-oxo-l-norleucine formed by reaction of the protein with 6-diazo-5-oxo-l- norleucine
Author: a. u. singer, y. kim, i. dementieva, e. vinokour, a. joachimiak, a. savchenko, a. yakunin
Keywords: ybas glutaminase, don, hydrolase
- 3brt.pdb.
transferase/transcription 21-dec-07 3brt
Title: nemo/ikk association domain structure
Author: l. f. silvian
Keywords: coiled coil, disease mutation, ectodermal dysplasia, host-virus interaction, nucleus, transcription, transcription regulation, transferase/transcription complex
- 3brv.pdb.
transferase/transcription 21-dec-07 3brv
Title: nemo/ikkb association domain structure
Author: l. f. silvian
Keywords: coiled coil, disease mutation, ectodermal dysplasia, host-virus interaction, nucleus, transcription, transcription regulation, transferase/transcription complex
- 3bs1.pdb.
transcription regulator 21-dec-07 3bs1
Mg Br
Title: structure of the staphylococcus aureus agra lyttr domain bound to dna reveals a beta fold with a novel mode of binding
Author: d. j. sidote, c. barbieri, t. wu, a. m. stock
Keywords: agra, response regulator, dna binding domain, activator, cytoplasm, dna-binding, phosphoprotein, transcription, transcription regulation, two-component regulatory system, transcription regulator
- 3bs9.pdb.
rna binding protein 22-dec-07 3bs9
I
Title: x-ray structure of human tia-1 rrm2
Author: a. o. kumar, c. l. kielkopf
Keywords: rrm, rna binding domain, rbd, rna splicing, apoptosis, phosphoprotein, rna-binding, rna binding protein
- 3bv2.pdb.
transferase 04-jan-08 3bv2
Title: morpholino pyrrolotriazine p38 alpha map kinase inhibitor compound 30
Author: j. s. sack
Keywords: kinase, transferase, p38 map kinase, alternative splicing, atp-binding, cytoplasm, nucleotide-binding, nucleus, phosphoprotein
- 3bv3.pdb.
transferase 04-jan-08 3bv3
Title: morpholino pyrrolotriazine p38 alpha map kinase inhibitor compound 2
Author: j. s. sack
Keywords: kinase, transferase, p38 map kinase, alternative splicing, atp-binding, cytoplasm, nucleotide-binding, nucleus, phosphoprotein
- 3bva.pdb.
hydrolase 05-jan-08 3bva
Title: cystal structure of hiv-1 active site mutant d25n and p2-nc analog inhibitor
Author: f. liu, i. t. weber
Keywords: active site, mutation, d25n, hydrolase
- 3bvb.pdb.
hydrolase 05-jan-08 3bvb
Cl Na
Title: cystal structure of hiv-1 active site mutant d25n and inhibitor darunavir
Author: f. liu, i. t. weber
Keywords: virion, zinc, zinc-finger
- 3bvd.pdb.
oxidoreductase 07-jan-08 3bvd
Cu Fe Xe
Title: structure of surface-engineered cytochrome ba3 oxidase from thermus thermophilus under xenon pressure, 100psi 5min
Author: v. m. luna, y. chen, j. a. fee, c. d. stout
Keywords: heme, integral membrane protein, copper, electron transport, hydrogen ion transport, ion transport, iron, metal-binding, oxidoreductase, respiratory chain, transmembrane, transport, formylation, xeno...
- 3bxq.pdb.
hormone 14-jan-08 3bxq
He Hg Zn
Title: the structure of a mutant insulin uncouples receptor binding from protein allostery. an electrostatic block to the tr transition
Author: z. l. wan, k. huang, s. q. hu, j. whittaker, m. a. weiss
Keywords: electrostatic block, protein allostery, receptor binding, hormone
- 3bzm.pdb.
isomerase 18-jan-08 3bzm
Title: crystal structure of open form of menaquinone-specific isochorismate synthase, menf
Author: j. f. parsons, k. m. shi, j. e. ladner
Keywords: isochorismate, menaquinone, isomerase, menaquinone biosynthesis
- 3bzn.pdb.
isomerase 18-jan-08 3bzn
Mg
Title: crystal structure of open form of menaquinone-specific isochorismate synthase, menf
Author: j. f. parsons, k. m. shi, j. e. ladner
Keywords: isochorismate, menaquinone, isomerase, menaquinone biosynthesis
- 3c0v.pdb.
plant protein 21-jan-08 3c0v
Ta Br Na
Title: crystal structure of cytokinin-specific binding protein in complex with cytokinin and ta6br12
Author: o. pasternak, a. bujacz, j. biesiadka, g. bujacz, m. sikorski, m. jaskolski
Keywords: ta6br12 complex, cytokinins, zeatin, pathogenesis- related proteins, plant defense, plant protein
- 3c17.pdb.
hydrolase 22-jan-08 3c17
Cl Na
Title: hexagonal crystal structure of precursor e. coli isoaspartyl peptidase/l-asparaginase (ecaiii) with active- site t179a mutation
Author: k. michalska, a. hernandez-santoyo, m. jaskolski
Keywords: asparaginase, ntn-hydrolase, autoproteolysis, precursor
- 3c2g.pdb.
cell adhesion/transcription 24-jan-08 3c2g
Se
Title: crystal complex of sys-1/pop-1 at 2.5a resolution
Author: j. liu, b. t. phillips, m. f. amaya, j. kimble, w. xu
Keywords: crystal structure, phylogeny, sys-1, pop-1, caenorhabditis elegans, developmental protein, dna-binding, nucleus, cell adhesion/transcription complex
- 3c2h.pdb.
cell adhesion 25-jan-08 3c2h
Title: crystal structure of sys-1 at 2.6a resolution
Author: j. liu, b. t. phillips, m. f. amaya, j. kimble, w. xu
Keywords: caenorhabditis elegans, beta-catenin, wnt, cell adhesion
- 3c2i.pdb.
transcription regulator 25-jan-08 3c2i
Se
Title: the crystal structure of methyl-cpg binding domain of human mecp2 in complex with a methylated dna sequence from bdnf
Author: k. l. ho, i. w. mcnae, l. schmiedeberg, r. j. klose, a. p. bird, m. d. walkinshaw
Keywords: protein-methylated dna complex, asx-st-motif, alternative splicing, chromosomal rearrangement, disease mutation, dna-binding, nucleus, phosphoprotein, polymorphism, repressor, transcription regulator
- 3c2k.pdb.
transferase/dna 25-jan-08 3c2k
Cl Mn Na
Title: dna polymerase beta with a gapped dna substrate and dumpnpp with manganese in the active site
Author: v. k. batra, w. a. beard, d. d. shock, l. c. pedersen, s. h. wilson
Keywords: nucleus, polymorphism, sodium, transferase/dna complex
- 3c2l.pdb.
transferase/dna 25-jan-08 3c2l
Mn Na
Title: ternary complex of dna polymerase beta with a c:dapcpp mismatch in the active site
Author: v. k. batra, w. a. beard, d. d. shock, l. c. pedersen, s. h. wilson
Keywords: polymorphism, sodium, transferase/dna complex
- 3c2m.pdb.
transferase, lyase/dna 25-jan-08 3c2m
Mn Na
Title: ternary complex of dna polymerase beta with a g:dapcpp mismatch in the active site
Author: v. k. batra, w. a. beard, d. d. shock, l. c. pedersen, s. h. wilson
Keywords: polymorphism, sodium, transferase, lyase/dna complex
- 3c4w.pdb.
transferase 30-jan-08 3c4w
Cl Mg
Title: crystal structure of g protein coupled receptor kinase 1 bound to atp and magnesium chloride at 2.7a
Author: p. singh, j. j. g. tesmer
Keywords: nucleotide- binding, phosphoprotein, prenylation, serine/threonine- protein kinase, transferase
- 3c4x.pdb.
transferase 30-jan-08 3c4x
Cl Mg
Title: crystal structure of g protein coupled receptor kinase 1 bound to atp and magnesium chloride at 2.9a
Author: p. singh, j. j. g. tesmer
Keywords: phosphoprotein, prenylation, serine/threonine-protein kinase, transferase
- 3c4y.pdb.
transferase 30-jan-08 3c4y
Title: crystal structure of apo form of g protein coupled receptor kinase 1 at 7.51a
Author: p. singh, j. j. g. tesmer
Keywords: prenylation, serine/threonine-protein kinase, transferase
- 3c4z.pdb.
transferase 30-jan-08 3c4z
Cl Mg
Title: crystal structure of g protein coupled receptor kinase 1 bound to adp and magnesium chloride at 1.84a
Author: p. singh, j. j. g. tesmer
Keywords: phosphoprotein, prenylation, serine/threonine-protein kinase, transferase
- 3c50.pdb.
transferase 30-jan-08 3c50
Cl Mg
Title: crystal structure of g protein coupled receptor kinase 1 bound to adp and magnesium chloride at 2.6a
Author: p. singh, j. j. g. tesmer
Keywords: phosphoprotein, prenylation, serine/threonine-protein kinase, transferase
- 3c51.pdb.
transferase 30-jan-08 3c51
Mg Br
Title: crystal structure of g protein coupled receptor kinase 1 bound to adp and magnesium chloride at 3.55a
Author: p. singh, j. j. g. tesmer
Keywords: phosphoprotein, prenylation, serine/threonine-protein kinase, transferase
- 3c66.pdb.
transferase 02-feb-08 3c66
Title: yeast poly(a) polymerase in complex with fip1 residues 80- 105
Author: a. bohm, g. meinke
Keywords: mrna processing, nucleus, rna- binding, transferase, phosphoprotein
- 3c79.pdb.
choline-binding protein 06-feb-08 3c79
Cl
Title: crystal structure of aplysia californica achbp in complex with the neonicotinoid imidacloprid
Author: t. t. talley, m. harel, r. e. hibbs, m. tomizawa, j. e. casida, p. w. taylor
Keywords: receptor, choline-binding protein
- 3c84.pdb.
choline-binding protein 08-feb-08 3c84
Cl Mg
Title: crystal structure of a complex of achbp from aplysia californica and the neonicotinoid thiacloprid
Author: t. t. talley, m. harel, r. e. hibbs, m. tomizawa, j. e. casida, p. w. taylor
Keywords: neonicotinoid, receptor, choline-binding protein
- 3c9a.pdb.
hormone/signaling protein 15-feb-08 3c9a
Br
Title: high resolution crystal structure of argos bound to the egf domain of spitz
Author: d. e. klein, s. e. stayrook, f. shi, k. narayan, m. a. lemmon
Keywords: neurogenesis, transmembrane, hormone/signaling protein complex
- 3ca7.pdb.
hormone/signaling protein 19-feb-08 3ca7
Title: high resolution crystal structure of the egf domain of spitz
Author: d. e. klein, s. e. stayrook, m. a. lemmon
Keywords: argos, egf, developmental protein, differentiation, egf-like domain, endoplasmic reticulum, glycoprotein, golgi apparatus, membrane, neurogenesis, transmembrane, hormone/signaling protein complex
- 3ca8.pdb.
structural genomics, unknown function 19-feb-08 3ca8
Title: crystal structure of escherichia coli ydcf, an s-adenosyl-l- methionine utilizing enzyme
Author: k. lim, k. chao, c. lehmann, o. herzberg, structure 2 function project (s2f)
Keywords: alpha/beta fold, helix bundle, structural genomics, structure 2 function project, s2f, structural genomics, unknown function
- 3cc2.pdb.
ribosome 23-feb-08 3cc2
Cl Mg K Na Cd
Title: the refined crystal structure of the haloarcula marismortui large ribosomal subunit at 2.4 angstrom resolution with rrna sequence for the 23s rrna and genome-derived sequences for r-proteins
Author: g. gurel, g. blaha
Keywords: ribonucleoprotein, ribosomal protein, rna-binding, rrna-binding, trna-binding, metal-binding, zinc, zinc-finger, acetylation, ribosome
- 3cc4.pdb.
ribosome 24-feb-08 3cc4
Cl Sr Mg K Na Cd
Title: co-crystal structure of anisomycin bound to the 50s ribosomal subunit
Author: g. blaha, g. gurel
Keywords: large ribosomal subunit, haloarcula marismortui, co-crystal, anisomycin, ribosome
- 3cc7.pdb.
ribosome 25-feb-08 3cc7
Cl Sr Mg K Na Cd
Title: structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation c2487u
Author: g. blaha, g. gurel
Keywords: c2487u, large ribosomal subunit, 23s rrna, ribonucleoprotein, ribosomal protein, rna-binding, rrna-binding, trna-binding, metal-binding, zinc, zinc- finger, acetylation, ribosome
- 3cce.pdb.
ribosome 25-feb-08 3cce
Cl Sr Mg K Na Cd
Title: structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation u2535a
Author: g. blaha, g. gurel
Keywords: ribosome
- 3ccj.pdb.
ribosome 26-feb-08 3ccj
Cl Sr Mg K Na Cd
Title: structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation c2534u
Author: g. blaha, g. gurel
Keywords: 23s rrna, large ribosomal subunit, ribosome
- 3ccl.pdb.
ribosome 26-feb-08 3ccl
Cl Sr Mg K Na Cd
Title: structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation u2535c. density for anisomycin is visible but not included in model.
Author: g. blaha, g. gurel
Keywords: 23s rrna, large ribosomal subunit, ribosome
- 3ccm.pdb.
ribosome 26-feb-08 3ccm
Cl Sr Mg K Na Cd
Title: structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation g2611u
Author: g. blaha, g. gurel
Keywords: 23s rrna, large ribosomal subunit, ribosome
- 3ccq.pdb.
ribosome 26-feb-08 3ccq
Cl Sr Mg K Na Cd
Title: structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation a2488u
Author: g. blaha, g. gurel
Keywords: ribosome
- 3ccr.pdb.
ribosome 26-feb-08 3ccr
Cl Sr Mg K Na Cd
Title: structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation a2488c. density for anisomycin is visible but not included in the model.
Author: g. blaha, g. gurel
Keywords: 23s rrna, large ribosomal subunit, ribosome
- 3ccs.pdb.
ribosome 26-feb-08 3ccs
Cl Sr Mg K Na Cd
Title: structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation g2482a
Author: g. blaha, g. gurel
Keywords: 23s rrna, large ribosomal subunit, ribosome
- 3ccu.pdb.
ribosome 26-feb-08 3ccu
Cl Sr Mg K Na Cd
Title: structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation g2482c
Author: g. blaha, g. gurel
Keywords: 23s rrna, large ribosomal subunit, ribosome
- 3ccv.pdb.
ribosome 26-feb-08 3ccv
Cl Sr Mg K Na Cd
Title: structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation g2616a
Author: g. blaha, g. gurel
Keywords: 23s rrna, large ribosomal subunit, ribosome
- 3cd6.pdb.
ribosome 26-feb-08 3cd6
Cl Sr Mg K Na Cd
Title: co-cystal of large ribosomal subunit mutant g2616a with cc- puromycin
Author: g. blaha, g. gurel
Keywords: 23s rrna, large ribosomal subunit, cc- puromycin, ribosome
- 3cen.pdb.
hydrolase 29-feb-08 3cen
Cl
Title: factor xa in complex with the inhibitor n-(2-(((5-chloro-2- pyridinyl) amino)sulfonyl)phenyl)-4-(2-oxo-1(2h)- pyridinyl)benzamide
Author: c. -h. chang
Keywords: hydroxylation, polymorphism, zymogen
- 3cf0.pdb.
transport protein 01-mar-08 3cf0
Title: structure of d2 subdomain of p97/vcp in complex with adp
Author: j. m. davies, a. t. brunger, w. i. weis
Keywords: p97/vcp, erad, cdc48, acetylation, atp-binding, cytoplasm, lipid-binding, nucleotide-binding, nucleus, phosphoprotein, transport, ubl conjugation pathway, transport protein
- 3cgu.pdb.
hormone/signaling protein 06-mar-08 3cgu
Title: crystal structure of unliganded argos
Author: d. e. klein, s. e. stayrook, m. a. lemmon
Keywords: spitz, egf, egfr inhibitor, developmental protein, glycoprotein, secreted, sensory transduction, vision, hormone/signaling protein complex
- 3cgy.pdb.
transferase 06-mar-08 3cgy
Cl
Title: crystal structure of salmonella sensor kinase phoq catalytic domain in complex with radicicol
Author: m. t. guarnieri, l. zhang, j. shen, r. zhao
Keywords: two-component regulatory system, virulence
- 3cgz.pdb.
transferase 06-mar-08 3cgz
Title: crystal structure of salmonella sensor kinase phoq catalytic domain
Author: m. t. guarnieri, l. zhang, j. shen, r. zhao
Keywords: two-component regulatory system, virulence
- 3ci0.pdb.
protein transport 10-mar-08 3ci0
Cl Ca Se
Title: the crystal structure of the gspk-gspi-gspj complex from enterotoxigenic escherichia coli type 2 secretion system
Author: k. v. korotkov, w. g. j. hol
Keywords: pseudopilus, type 4 pilin biogenesis, methylation, protein transport
- 3ci6.pdb.
transferase 10-mar-08 3ci6
Se
Title: crystal structure of the gaf domain from acinetobacter phosphoenolpyruvate-protein phosphotransferase
Author: m. e. cuff, g. shackelford, y. kim, a. joachimiak, midwest center for structural genomics (mcsg)
Keywords: phosphotransferase system, pyruvate, sugar transport, transport
- 3cii.pdb.
immune system 11-mar-08 3cii
Title: structure of nkg2a/cd94 bound to hla-e
Author: r. k. strong, b. k. kaiser, j. c. pizarro
Keywords: receptor, signal-anchor, immune system
- 3cit.pdb.
transferase 11-mar-08 3cit
Se
Title: crystal structure of the gaf domain of a putative sensor histidine kinase from pseudomonas syringae pv. tomato
Author: m. e. cuff, h. li, j. abdullah, a. joachimiak, midwest center for structural genomics (mcsg)
Keywords: structural genomics, sensor histidine kinase, pseudomonas syringae, psi-2, protein structure initiative, midwest center for structural genomics, mcsg, transferase
- 3cjq.pdb.
transferase/ribosomal protein 13-mar-08 3cjq
I
Title: ribosomal protein l11 methyltransferase (prma) in complex with dimethylated ribosomal protein l11 in space group p212121
Author: h. demirci, s. t. gregory, a. e. dahlberg, g. jogl
Keywords: post- translational modification, multi-specific trimethylation, cytoplasm, ribonucleoprotein, ribosomal protein, rna- binding, rrna-binding, transferase/ribosomal protein complex
- 3cjr.pdb.
transferase/ribosomal protein 13-mar-08 3cjr
Title: ribosomal protein l11 methyltransferase (prma) in complex with ribosomal protein l11 (k39a) and inhibitor sinefungin.
Author: h. demirci, s. t. gregory, a. e. dahlberg, g. jogl
Keywords: post- translational modification, multi-specific trimethylation, cytoplasm, ribonucleoprotein, ribosomal protein, rna- binding, rrna-binding, transferase/ribosomal protein complex
- 3cjs.pdb.
transferase/ribosomal protein 13-mar-08 3cjs
Title: minimal recognition complex between prma and ribosomal protein l11
Author: h. demirci, s. t. gregory, a. e. dahlberg, g. jogl
Keywords: post- translational modification, multi-specific trimethylation, cytoplasm, ribonucleoprotein, ribosomal protein, rna- binding, rrna-binding, transferase/ribosomal protein complex
- 3cjt.pdb.
transferase/ribosomal protein 13-mar-08 3cjt
Cl
Title: ribosomal protein l11 methyltransferase (prma) in complex with dimethylated ribosomal protein l11
Author: h. demirci, s. t. gregory, a. e. dahlberg, g. jogl
Keywords: post- translational modification, multi-specific trimethylation, cytoplasm, ribonucleoprotein, ribosomal protein, rna- binding, rrna-binding, transferase/ribosomal protein complex
- 3cju.pdb.
transferase/ribosomal protein 13-mar-08 3cju
Cl I
Title: ribosomal protein l11 methyltransferase (prma) in complex with trimethylated ribosomal protein l11
Author: h. demirci, s. t. gregory, a. e. dahlberg, g. jogl
Keywords: post- translational modification, multi-specific trimethylation, cytoplasm, ribonucleoprotein, ribosomal protein, rna- binding, rrna-binding, transferase/ribosomal protein complex
- 3ck9.pdb.
sugar binding protein 14-mar-08 3ck9
Ca
Title: b. thetaiotaomicron susd with maltoheptaose
Author: n. m. koropatkin, e. c. martens, j. i. gordon, t. j. smith
Keywords: carbohydrate binding, starch binding, sugar binding protein
- 3ckz.pdb.
viral protein, hydrolase 18-mar-08 3ckz
Ca
Title: n1 neuraminidase h274y + zanamivir
Author: p. colllins, l. f. haire, y. p. lin, j. liu, r. j. russell, p. a. walker, j. j. skehel, s. r. martin, a. j. hay, s. j. gamblin
Keywords: neuraminidase, h274y, zanamivir, glycosidase, hydrolase, membrane, transmembrane, virion, viral protein, hydrolase
- 3cl0.pdb.
viral protein, hydrolase 18-mar-08 3cl0
Ca
Title: n1 neuraminidase h274y + oseltamivir
Author: p. collins, l. f. haire, y. p. lin, j. liu, r. j. russell, p. a. walker, j. j. skehel, s. r. martin, a. j. hay, s. j. gamblin
Keywords: neuraminidase, h274y, oseltamivir, glycosidase, hydrolase, membrane, transmembrane, virion, viral protein, hydrolase
- 3cl2.pdb.
viral protein, hydrolase 18-mar-08 3cl2
Title: n1 neuraminidase n294s + oseltamivir
Author: p. collins, l. f. haire, y. p. lin, j. liu, r. j. russell, p. a. walker, j. j. skehel, s. r. martin, a. j. hay, s. j. gamblin
Keywords: neuraminidase, n294s, oseltamivir, glycosidase, hydrolase, membrane, transmembrane, virion, viral protein, hydrolase
- 3cmt.pdb.
recombination/dna 24-mar-08 3cmt
Mg F Al
Title: mechanism of homologous recombination from the reca- ssdna/dsdna structures
Author: z. chen, h. yang, n. p. pavletich
Keywords: atp-binding, cytoplasm, dna damage, dna recombination, dna repair, dna-binding, nucleotide-binding, sos response, stress response, recombination/dna complex
- 3cmu.pdb.
recombination/dna 24-mar-08 3cmu
Mg F Al
Title: mechanism of homologous recombination from the reca- ssdna/dsdna structures
Author: n. p. pavletich
Keywords: recombination/dna complex
- 3cmv.pdb.
recombination 24-mar-08 3cmv
Mg
Title: mechanism of homologous recombination from the reca- ssdna/dsdna structures
Author: n. p. pavletich
Keywords: recombination
- 3cmw.pdb.
recombination/dna 24-mar-08 3cmw
Mg F Al
Title: mechanism of homologous recombination from the reca- ssdna/dsdna structures
Author: n. p. pavletich
Keywords: recombination/dna complex
- 3cmx.pdb.
recombination/dna 24-mar-08 3cmx
Mg F Al
Title: mechanism of homologous recombination from the reca- ssdna/dsdna structures
Author: n. p. pavletich
Keywords: recombination/dna complex
- 3cnf.pdb.
virus 25-mar-08 3cnf
(cryo-electron microscopy)
Title: 3.88 angstrom structure of cytoplasmic polyhedrosis virus by cryo-electron microscopy
Author: x. yu, l. jin, z. h. zhou
Keywords: capsid protein, turret protein, polyhedrin-binding domain, guanylyltransferase domain, icosahedral virus
- 3cqs.pdb.
ribonucleic acid 03-apr-08 3cqs
Co
Title: a 3'-oh, 2',5'-phosphodiester substitution in the hairpin ribozyme active site reveals similarities with protein ribonucleases
Author: a. t. torelli, r. c. spitale, j. krucinska, j. e. wedekind
Keywords: 5' phosphodiester; hairpin ribozyme; reaction- intermediate; transition-state stabilization; ribonuclease; phosphoryl-transfer, rna
- 3cre.pdb.
membrane protein 07-apr-08 3cre
(cryo-electron microscopy)
Title: electron microscopy model of the saf pilus- type a
Author: o. salih, h. remaut, g. waksman, e. v. orlova
Keywords: type a saf pilus, fibril protein, membrane protein
- 3crf.pdb.
membrane protein 07-apr-08 3crf
(cryo-electron microscopy)
Title: electron microscopy model of the saf pilus- type b
Author: o. salih, h. remaut, g. waksman, e. v. orlova
Keywords: type b saf pilus, fibril protein, membrane protein
- 3cst.pdb.
transferase 10-apr-08 3cst
F Ru
Title: crystal structure of pi3k p110gamma catalytical domain in complex with organoruthenium inhibitor e5e2
Author: p. xie, r. marmorstein
Keywords: pi3k, transferase
- 3cwq.pdb.
structural genomics, unknown function 22-apr-08 3cwq
Se
Title: crystal structure of chromosome partitioning protein (para) in complex with adp from synechocystis sp. northeast structural genomics consortium target sgr89
Author: f. forouhar, h. neely, j. seetharaman, l. mao, r. xiao, h. janjua, m. maglaqui, e. l. foote, d. lee, j. k. everett, t. b. acton, g. t. montelione, l. tong, j. f. hunt, northeast structural genomics consortium (nesg)
Keywords: structural genomics, psi-2, protein structure initiative, northeast structural genomics consortium, nesg, structural genomics, unknown function
- 3cxa.pdb.
antibiotic 24-apr-08 3cxa
Title: crystal structure of the complex of peptidoglycan recognition protein with alpha-d-glucopyranosyl alpha-d- glucopyranoside at 3.4 a resolution
Author: k. balaji, p. sharma, n. singh, m. sinha, a. bhushan, p. kaur, s. sharma, t. p. singh
Keywords: complex, trehalose, immune response, secreted, antimicrobial, pgrp, antibiotic
- 3cz6.pdb.
protein binding 28-apr-08 3cz6
Se
Title: crystal structure of the rap1 c-terminus
Author: e. a. feeser, c. wolberger
Keywords: activator, chromosomal protein, dna-binding, nucleus, phosphoprotein, repressor, telomere, transcription, transcription regulation, dna binding protein, protein binding
- 3czo.pdb.
lyase 29-apr-08 3czo
Se
Title: crystal structure of double mutant phenylalanine ammonia- lyase from anabaena variabilis
Author: r. c. stevens, l. wang
Keywords: cytoplasm
- 3d00.pdb.
structural genomics, unknown function 30-apr-08 3d00
Cl Zn Se
Title: crystal structure of tungsten formylmethanofuran dehydrogenase subunit e (fwde) (yp_460196.1) from syntrophus aciditrophicus sb at 1.90 a resolution
Author: joint center for structural genomics (jcsg)
Keywords: tungsten formylmethanofuran dehydrogenase subunit e (fwde), structural genomics, joint center for structural genomics, jcsg, protein structure initiative, psi-2, structural genomics, unknown function
- 3d0d.pdb.
hydrolase 01-may-08 3d0d
Co
Title: crystal structure of an encephalitozoon cuniculi methionine aminopeptidase type 2 with angiogenesis inhibitor tnp470 bound
Author: j. alvarado, m. russell, a. zhang, j. adams, r. toro, s. k. burley, l. m. weiss, s. c. almo, new york structural genomix research consortium (nysgxrc)
Keywords: nysgxrc, cobalt, hydrolase, metal-binding, protease
- 3d0w.pdb.
structural genomics, unknown function 02-may-08 3d0w
Se
Title: crystal structure of yflh protein from bacillus subtilis. northeast structural genomics consortium target sr326
Author: j. seetharaman, a. p. kuzin, h. neely, f. forouhar, s. min, l. zhao, y. fang, l. owens, l-c. ma, r. xiao, j. liu, m. c. baran, t. b. acton, b. rost, g. t. montelione, j. f. hunt, l. tong, northeast structural genomics consortium (nesg)
Keywords: gram-positive bacterium, bacillus subtilis, structural genomics, psi-2, protein structure initiative, northeast structural genomics consortium, nesg, structural genomics, unknown function
- 3d1c.pdb.
oxidoreductase 05-may-08 3d1c
Se
Title: crystal structure of flavin-containing putative monooxygenase (np_373108.1) from staphylococcus aureus mu50 at 2.40 a resolution
Author: joint center for structural genomics (jcsg)
Keywords: pyridine nucleotide-disulphide oxidoreductase
- 3d1u.pdb.
transferase 06-may-08 3d1u
Cl Se
Title: crystal structure of putative fructosamine-3-kinase (yp_290396.1) from thermobifida fusca yx-er1 at 1.85 a resolution
Author: joint center for structural genomics (jcsg)
Keywords: putative fructosamine-3-kinase, structural genomics, joint center for structural genomics, jcsg, protein structure initiative, psi-2, unknown function, transferase
- 3d2l.pdb.
transferase 08-may-08 3d2l
Mg Se
Title: crystal structure of sam-dependent methyltransferase (zp_00538691.1) from exiguobacterium sp. 255-15 at 1.90 a resolution
Author: joint center for structural genomics (jcsg)
Keywords: sam-dependent methyltransferase, structural genomics, joint center for structural genomics, jcsg, protein structure initiative, psi-2, methyltransferase domain
- 3d2t.pdb.
hormone 08-may-08 3d2t
F
Title: human transthyretin (ttr) complexed with diflunisal
Author: s. k. palaninathan, j. w. kelly, j. c. sacchettini
Keywords: hormone/growth factor complex
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