Recent PDB releases or updates: week of 30 January 2009
- 1o0k.pdb.
deoxyribonucleic acid 22-feb-03 1o0k
Na
Title: structure of the first parallel dna quadruplex-drug complex
Author: g. r. clark, p. d. pytel, c. j. squire, s. neidle
Keywords: parallel quadruplex
- 1v7r.pdb.
hydrolase 22-dec-03 1v7r
Title: structure of nucleotide triphosphate pyrophosphatase from pyrococcus horikoshii ot3
Author: n. k. lokanath, n. kunishima, riken structural genomics/proteomics initiative (rsgi)
Keywords: structural genomics, riken structural genomics/proteomics initiative, rsgi
- 1wzc.pdb.
hydrolase 04-mar-05 1wzc
Mg
Title: crystal structure of pyrococcus horikoshii mannosyl-3- phosphoglycerate phosphatase complexed with mg2+ and phosphate
Author: t. kawamura, n. watanabe, i. tanaka
Keywords: phosphatase
- 2ahs.pdb.
hydrolase 28-jul-05 2ahs
Cl Na
Title: crystal structure of the catalytic domain of human tyrosine receptor phosphatase beta
Author: e. ugochukwu, j. eswaran, a. barr, o. gileadi, f. sobott, n. burgess, l. ball, j. bray, f. von delft, j. debreczeni, g. bunkoczi, a. turnbull, s. das, j. weigel, a. edwards, c. arrowsmith, m. sundstrom, s. knapp, structural genomics consortium (sgc)
Keywords: beta, human, structural genomics, structural genomics consortium, sgc
- 2b49.pdb.
hydrolase 23-sep-05 2b49
Title: crystal structure of the catalytic domain of protein tyrosine phosphatase, non-receptor type 3
Author: e. ugochukwu, c. arrowsmith, a. barr, g. bunkoczi, s. das, j. debreczeni, a. edwards, j. eswaran, s. knapp, m. sundstrom, a. turnbull, f. von delft, j. weigelt, structural genomics consortium (sgc)
Keywords: non-receptor type, human, structural genomics, structural genomics consortium, sgc
- 2dc1.pdb.
oxidoreductase 19-dec-05 2dc1
Title: crystal structure of l-aspartate dehydrogenase from hyperthermophilic archaeon archaeoglobus fulgidus
Author: k. yoneda, h. sakuraba, h. tsuge, t. ohshima
Keywords: nad
- 2djg.pdb.
hydrolase 02-apr-06 2djg
Cl
Title: re-refinement of the native structure of human dipeptidyl peptidase i (cathepsin c)
Author: a. molgaard, j. arnau, c. lauritzen, s. larsen, g. petersen, j. pedersen
Keywords: cysteine protease, cathepsin c, dipeptidyl peptidase i, hydrolase
- 2dst.pdb.
structural genomics, unknown function 06-jul-06 2dst
Title: crystal structure analysis of tt1977
Author: y. xie, s. kishisita, k. murayama, m. shirozu, l. chen, z. j. liu, b. c. wang, riken structural genomics/proteomics initiative (rsgi)
Keywords: structural genomics, nppsfa, national project on protein structural and functional analyses, riken structural genomics/proteomics initiative, rsgi
- 2esc.pdb.
signaling protein 26-oct-05 2esc
Title: crystal structure of a 40 kda protective signalling protein from bovine (spc-40) at 2.1 a resolution
Author: j. kumar, a. s. ethayathulla, d. b. srivastav, s. sharma, a. srinivasan, t. p. singh
Keywords: crystal structure,
- 2gjt.pdb.
hydrolase 31-mar-06 2gjt
Cl
Title: crystal structure of the human receptor phosphatase ptpro
Author: a. barr, e. ugochukwu, j. eswaran, s. das, f. niesen, p. savitsky, a. turnbull, m. sundstrom, c. arrowsmith, a. edwards, j. weigelt, f. von delft, e. papagrigoriou, s. knapp, structural genomics consortium (sgc)
Keywords: ptpro, glepp1, ptpu2, structural genomics, structural genomics consortium, sgc
- 2h4v.pdb.
hydrolase 25-may-06 2h4v
Cl Na
Title: crystal structure of the human tyrosine receptor phosphatase gamma
Author: e. ugochukwu, a. barr, s. das, j. eswaran, p. savitsky, m. sundstrom, a. edwards, c. arrowsmith, j. weigelt, j. debreczeni, f. von delft, s. knapp, structural genomics consortium (sgc)
Keywords: gamma, human, structural genomics, structural genomics consortium, sgc
- 2job.pdb.
lipid binding protein 02-mar-07 2job
He Hg
(NMR, 15 structures)
Title: solution structure of an antilipopolysaccharide factor from shrimp and its possible lipid a binding site
Author: y. yang, h. boze, p. chemardin, a. padilla, g. moulin, a. tassanakajon, m. pugniere, f. roquet, y. gueguen, e. bachere, a. aumelas
Keywords: lipid a binding protein, endotoxin, lipid binding protein
- 2jw4.pdb.
signaling protein 05-oct-07 2jw4
He Hg
(NMR, 20 structures)
Title: nmr solution structure of the n-terminal sh3 domain of human nckalpha
Author: c. m. santiveri, a. borroto, l. simon, m. rico, a. r. ortiz, b. alarcon, m. jimenez
Keywords: nmr, cytoplasm, phosphorylation, sh2 domain, signaling protein
- 2jzy.pdb.
transcription 22-jan-08 2jzy
He Hg
(solution NMR)
Title: solution structure of c-terminal effector domain of putative two-component-system response regulator involved in copper resistance from klebsiella pneumoniae
Author: k. hung, p. fang, c. chang, s. tsai, t. huang
Keywords: effector domain, dna-binding, phosphoprotein, plasmid, transcription, transcription regulation, two-component regulatory system
- 2k02.pdb.
metal binding protein 23-jan-08 2k02
He Hg
(solution NMR)
Title: solution structure of putative ferrous iron transport protein c (feoc) of klebsiella pneumoniae
Author: k. hung, y. lin, j. chen, t. huang
Keywords: feoc, klebsiella pneumoniae, nmr, iron-sulfur, metal-binding, metal binding protein
- 2k1w.pdb.
metal binding protein 17-mar-08 2k1w
He Hg Ca
(solution NMR)
Title: nmr solution structure of m-crystallin in calcium loaded form(holo).
Author: r. barnwal, m. jobby, k. devi, y. sharma, k. chary
Keywords: eye lens, archaea, protein, evolution, metal binding protein
- 2k1x.pdb.
metal binding protein 17-mar-08 2k1x
He Hg
(solution NMR)
Title: nmr solution structure of m-crystallin in calcium free form (apo).
Author: r. barnwal, m. jobby, k. devi, y. sharma, k. chary
Keywords: eye lens, archaea, cataract, evolution, metal binding protein
- 2k2x.pdb.
hydrolase inhibitor 15-apr-08 2k2x
He Hg
(solution NMR)
Title: solution structure of tick carboxypeptidase inhibitor at ph 3.5
Author: d. pantoja-uceda, f. blanco
Keywords: blood coagulation, fibrinolysis, metalloenzyme inhibitor, metalloprotease inhibitor, secreted, hydrolase inhibitor
- 2k2y.pdb.
hydrolase inhibitor 15-apr-08 2k2y
He Hg
(solution NMR)
Title: solution structure of the folded domain of intermediate iiia of tick carboxypeptidase inhibitor
Author: d. pantoja-uceda, f. blanco
Keywords: blood coagulation, fibrinolysis, metalloenzyme inhibitor, metalloprotease inhibitor, secreted, hydrolase inhibitor
- 2k2z.pdb.
hydrolase inhibitor 15-apr-08 2k2z
He Hg
(solution NMR)
Title: solution structure of the folded domain of intermediate iiib of tick carboxypeptidase inhibitor
Author: d. pantoja-uceda, f. blanco
Keywords: blood coagulation, fibrinolysis, metalloenzyme inhibitor, metalloprotease inhibitor, secreted, hydrolase inhibitor
- 2k4b.pdb.
dna binding protein 03-jun-08 2k4b
He Hg
(solution NMR)
Title: copr repressor structure
Author: f. cantini, l. banci, d. magnani, m. solioz
Keywords: winged helix
- 2k5u.pdb.
signaling protein 30-jun-08 2k5u
He Hg Ho
(solution NMR)
Title: solution structure of myirstoylated yeast arf1 protein, gdp- bound
Author: j. prestegard, y. liu
Keywords: arf1, myristoyl, myrsitoylated, gdp, er-golgi transport, golgi apparatus, gtp-binding, lipoprotein, myristate, nucleotide-binding, protein transport, transport, signaling protein
- 2k9h.pdb.
metal binding protein 13-oct-08 2k9h
He Hg Zn
(solution NMR)
Title: the hantavirus glycoprotein g1 tail contains a dual cchc- type classical zinc fingers
Author: d. f. estrada, d. m. boudreaux, d. zhong, s. c. st jeor, r. n. de guzman
Keywords: glycoprotein, zinc finger, cchc, metal binding protein
- 2ka3.pdb.
structural protein 30-oct-08 2ka3
He Hg
(solution NMR)
Title: structure of emilin-1 c1q-like domain
Author: g. verdone, a. corazza, s. a. colebrooke, d. o. cicero, t. eliseo, j. boyd, r. doliana, f. fogolari, p. viglino, a. colombatti, i. d. campbell, g. esposito
Keywords: c1q-like domain, homotrimeric protein complex, beta-sandwich, structural protein, cell adhesion, extracellular matrix
- 2kad.pdb.
membrane protein 04-nov-08 2kad
Hg
(solid-state NMR)
Title: magic-angle-spinning solid-state nmr structure of influenza a m2 transmembrane domain
Author: m. hong, s. d. cady, t. v. mishanina
Keywords: transport, virion, membrane protein
- 2kbv.pdb.
membrane protein 09-dec-08 2kbv
He Hg
(solution NMR)
Title: structural and functional analysis of tm xi of the nhe1 isoform of the na+/h+ exchanger
Author: b. l. lee, x. li, y. liu, b. d. sykes, l. fliegel
Keywords: peptide, nhe1, micelle, alternative splicing, antiport, glycoprotein, ion transport, membrane, phosphoprotein, sodium, sodium transport, transport, membrane protein
- 2kck.pdb.
structural genomics, unknown function 22-dec-08 2kck
He Hg
(solution NMR)
Title: nmr solution structure of the northeast structural genomics consortium (nesg) target mrr121a
Author: a. w. barb, h-w. lee, x. wang, d. lee, m. jiang, c. ciccosanti, r. xiao, r. nair, j. k. everett, g. v. t. swapna, t. b. acton, b. rost, g. t. montelione, j. h. prestegard, northeast structural genomics consortium (nesg)
Keywords: structural genomics, unknown function, psi-2, protein structure initiative, northeast structural genomics consortium, nesg
- 2npq.pdb.
transferase 29-oct-06 2npq
Title: a novel lipid binding site in the p38 alpha map kinase
Author: r. diskin, d. engelberg, o. livnah
Keywords: kinase, protein-lipid complex, transferase
- 2pqn.pdb.
apoptosis 02-may-07 2pqn
Title: crystal structure of yeast fis1 complexed with a fragment of yeast mdv1
Author: y. zhang, d. c. chan
Keywords: protein-protein complex, apoptosis
- 2pqr.pdb.
apoptosis 02-may-07 2pqr
Au
Title: crystal structure of yeast fis1 complexed with a fragment of yeast caf4
Author: y. zhang, d. c. chan
Keywords: protein-protein complex, apoptosis
- 2q6q.pdb.
cell cycle 05-jun-07 2q6q
Cl Co
Title: crystal structure of spc42p, a critical component of spindle pole body in budding yeast
Author: v. n. malashkevich, j. r. newman, p. s. kim
Keywords: spindle pole body, budding yeast, crystal structure, coiled coil, cell cycle
- 2qtm.pdb.
transferase 02-aug-07 2qtm
Co
Title: crystal structure of nicotinate mononucleotide adenylyltransferase
Author: v. c. sershon, b. d. santarsiero, a. d. mesecar
Keywords: nucleotidyltransferase, pyridine nucleotide biosynthesis, transferase
- 2qtn.pdb.
transferase 02-aug-07 2qtn
Mg
Title: crystal structure of nicotinate mononucleotide adenylyltransferase
Author: v. c. sershon, b. d. santarsiero, a. d. mesecar
Keywords: nucleotidyltransferase, pyridine nucleotide biosynthesis, transferase
- 2qtr.pdb.
transferase 02-aug-07 2qtr
Title: crystal structure of nicotinate mononucleotide adenylyltransferase
Author: v. c. sershon, b. d. santarsiero, a. d. mesecar
Keywords: nucleotidyltransferase, pyridine nucleotide biosynthesis, transferase
- 2r4l.pdb.
transport protein 31-aug-07 2r4l
Title: crystal structure of the long-chain fatty acid transporter fadl mutant p34a
Author: e. m. hearn, d. r. patel, b. w. lepore, m. indic, b. van den berg
Keywords: outer membrane protein, lipid transport, phage recognition, transmembrane, transport, transport protein
- 2r4n.pdb.
transport protein 31-aug-07 2r4n
Title: crystal structure of the long-chain fatty acid transporter fadl mutant n33a
Author: e. m. hearn, d. r. patel, b. w. lepore, m. indic, b. van den berg
Keywords: outer membrane protein, lipid transport, phage recognition, transmembrane, transport, transport protein
- 2r4o.pdb.
transport protein 31-aug-07 2r4o
Title: crystal structure of the long-chain fatty acid transporter fadl mutant delta npa
Author: e. m. hearn, d. r. patel, b. w. lepore, m. indic, b. van den berg
Keywords: outer membrane protein, lipid transport, phage recognition, transmembrane, transport, transport protein
- 2r4p.pdb.
transport protein 31-aug-07 2r4p
Title: crystal structure of the long-chain fatty acid transporter fadl mutant g212e
Author: e. m. hearn, d. r. patel, b. w. lepore, m. indic, b. van den berg
Keywords: outer membrane protein, lipid transport, phage recognition, transmembrane, transport, transport protein
- 2r88.pdb.
transport protein 10-sep-07 2r88
Title: crystal structure of the long-chain fatty acid transporter fadl mutant delta s3 kink
Author: e. m. hearn, d. r. patel, b. w. lepore, m. indic, b. van den berg
Keywords: outer membrane protein, lipid transport, phage recognition, transmembrane, transport, transport protein
- 2v1x.pdb.
hydrolase 30-may-07 2v1x
Cl Mg Zn
Title: crystal structure of human recq-like dna helicase
Author: a. c. w. pike, b. shrestha, n. burgess-brown, o. king, e. ugochukwu, s. watt, a. edwards, c. h. arrowsmith, j. weigelt, m. sundstrom, o. gileadi
Keywords: mismatch repair, nucleotide-binding, dna-binding, polymorphism, nuclear protein, atpase, helicase, hydrolase, atp-binding
- 2v5c.pdb.
hydrolase 02-oct-08 2v5c
Na Ca As
Title: family 84 glycoside hydrolase from clostridium perfringens, 2.1 angstrom structure
Author: e. ficko-blean, k. j. gregg, j. j. adams, j. h. hehemann, s. j. smith, m. czjzek, a. b. boraston
Keywords: clostridium perfringens, gh84, gh84c, hydrolase, coiled coil, family 84 glycoside hydrolase, carbohydrate binding module
- 2v5d.pdb.
hydrolase 02-oct-08 2v5d
Ca
Title: structure of a family 84 glycoside hydrolase and a family 32 carbohydrate-binding module in tandem from clostridium perfringens.
Author: e. ficko-blean, k. j. gregg, j. j. adams, j. h. hehemann, s. j. smith, m. czjzek, a. b. boraston
Keywords: glycosidase, clostridium perfringens, gh84, gh84c, cbm32, hydrolase, coiled coil, family 84 glycoside hydrolase, carbohydrate binding module
- 2vjy.pdb.
lyase 14-dec-07 2vjy
Mg
Title: pyruvate decarboxylase from kluyveromyces lactis in complex with the substrate analogue methyl acetylphosphonate
Author: s. kutter, g. wille, m. s. weiss, s. konig
Keywords: magnesium, flavoprotein
- 2vk1.pdb.
lyase 16-dec-07 2vk1
Mg
Title: crystal structure of the saccharomyces cerevisiae pyruvate decarboxylase variant d28a in complex with its substrate
Author: s. kutter, m. weik, m. s. weiss, s. konig
Keywords: branched-chain amino acid catabolism, substrate activation, thiamine diphosphate, magnesium, acetylation, metal-binding, decarboxylase
- 2vk4.pdb.
lyase 17-dec-07 2vk4
Mg
Title: crystal structure of pyruvate decarboxylase from kluyveromyces lactis
Author: s. kutter, s. relle, g. wille, m. s. weiss, s. konig
Keywords: decarboxylase, dimer of dimers, substrate activation, thiamine diphosphate, tdp, tpp, lyase, magnesium, flavoprotein, thiamine pyrophosphate, asymmetric active sites
- 2vk8.pdb.
lyase 17-dec-07 2vk8
Mg
Title: crystal structure of the saccharomyces cerevisiae pyruvate decarboxylase variant e477q in complex with its substrate
Author: s. kutter, m. weik, m. s. weiss, s. konig
Keywords: branched-chain amino acid catabolism, substrate activation, thiamine diphosphate, magnesium, acetylation, metal-binding, decarboxylase
- 2vq1.pdb.
immune system 10-mar-08 2vq1
Title: anti trimeric lewis x fab54-5c10-a
Author: d. c. de geus, a. m. m. van roon, e. a. j. thomassen, c. h. hokke, a. m. deelder, j. p. abrahams
Keywords: monoclonal antibody, receptor, diagnosis, schistosomiasis, carbohydrate recognition, immune system
- 2w1c.pdb.
transferase 17-oct-08 2w1c
F
Title: structure determination of aurora kinase in complex with inhibitor
Author: s. howard, v. berdini, j. a. boulstridge, m. g. carr, d. m. cross, j. curry, l. a. devine, t. r. early, l. fazal, a. l. gill, m. heathcote, s. maman, j. e. matthews, r. l. mcmenamin, e. f. navarro, m. a. o'brien, m. o'reilly, d. c. rees, m. reule, d. tisi, g. williams, m. vinkovic, p. g. wyatt
Keywords: aurora, kinase, inhibitor, nucleotide-binding, serine/threonine-protein kinase, transferase, atp-binding, polymorphism, phosphoprotein, cell cycle
- 2w1d.pdb.
transferase 17-oct-08 2w1d
Title: structure determination of aurora kinase in complex with inhibitor
Author: s. howard, v. berdini, j. a. boulstridge, m. g. carr, d. m. cross, j. curry, l. a. devine, t. r. early, l. fazal, a. l. gill, m. heathcote, s. maman, j. e. matthews, r. l. mcmenamin, e. f. navarro, m. a. o'brien, m. o'reilly, d. c. rees, m. reule, d. tisi, g. williams, m. vinkovic, p. g. wyatt
Keywords: serine/threonine-protein kinase, transferase, atp-binding, polymorphism, phosphoprotein, kinase, cancer, aurora, inhibitor, cell cycle
- 2w1e.pdb.
transferase 17-oct-08 2w1e
Title: structure determination of aurora kinase in complex with inhibitor
Author: s. howard, v. berdini, j. a. boulstridge, m. g. carr, d. m. cross, j. curry, l. a. devine, t. r. early, l. fazal, a. l. gill, m. heathcote, s. maman, j. e. matthews, r. l. mcmenamin, e. f. navarro, m. a. o'brien, m. o'reilly, d. c. rees, m. reule, d. tisi, g. williams, m. vinkovic, p. g. wyatt
Keywords: serine/threonine-protein kinase, transferase, atp-binding, polymorphism, phosphoprotein, kinase, cancer, aurora, inhibitor, cell cycle
- 2w1f.pdb.
transferase 17-oct-08 2w1f
Title: structure determination of aurora kinase in complex with inhibitor
Author: s. howard, v. berdini, j. a. boulstridge, m. g. carr, d. m. cross, j. curry, l. a. devine, t. r. early, l. fazal, a. l. gill, m. heathcote, s. maman, j. e. matthews, r. l. mcmenamin, e. f. navarro, m. a. o'brien, m. o'reilly, d. c. rees, m. reule, d. tisi, g. williams, m. vinkovic, p. g. wyatt
Keywords: aurora, kinase, inhibitor, nucleotide-binding, serine/threonine-protein kinase, transferase, atp-binding, polymorphism, phosphoprotein, cell cycle
- 2w1g.pdb.
transferase 17-oct-08 2w1g
Title: structure determination of aurora kinase in complex with inhibitor
Author: s. howard, v. berdini, j. a. boulstridge, m. g. carr, d. m. cross, j. curry, l. a. devine, t. r. early, l. fazal, a. l. gill, m. heathcote, s. maman, j. e. matthews, r. l. mcmenamin, e. f. navarro, m. a. o'brien, m. o'reilly, d. c. rees, m. reule, d. tisi, g. williams, m. vinkovic, p. g. wyatt
Keywords: aurora, kinase, inhibitor, nucleotide-binding, serine/threonine-protein kinase, transferase, atp-binding, polymorphism, phosphoprotein, cell cycle
- 2w1h.pdb.
transferase 17-oct-08 2w1h
Title: fragment-based discovery of the pyrazol-4-yl urea (at9283), a multi-targeted kinase inhibitor with potent aurora kinase activity
Author: s. howard, v. berdini, j. a. boulstridge, m. g. carr, d. m. cross, j. curry, l. a. devine, t. r. early, l. fazal, a. l. gill, m. heathcote, s. maman, j. e. matthews, r. l. mcmenamin, e. f. navarro, m. a. o'brien, m. o'reilly, d. c. rees, m. reule, d. tisi, g. williams, m. vinkovic, p. g. wyatt
Keywords: kinase, mitosis, cell cycle, transferase, serine/threonine-protein kinase, atp-binding, polymorphism, cell division, phosphoprotein, fragment screening, nucleotide-binding
- 2w1i.pdb.
transferase 17-oct-08 2w1i
Title: structure determination of aurora kinase in complex with inhibitor
Author: s. howard, v. berdini, j. a. boulstridge, m. g. carr, d. m. cross, j. curry, l. a. devine, t. r. early, l. fazal, a. l. gill, m. heathcote, s. maman, j. e. matthews, r. l. mcmenamin, e. f. navarro, m. a. o'brien, m. o'reilly, d. c. rees, m. reule, d. tisi, g. williams, m. vinkovic, p. g. wyatt
Keywords: nucleotide-binding, tyrosine-protein kinase, proto-oncogene, phosphoprotein, disease mutation, sh2 domain, transferase, atp-binding, polymorphism, kinase, cancer, aurora, membrane, inhibitor
- 2w3n.pdb.
lyase 13-nov-08 2w3n
Zn
Title: structure and inhibition of the co2-sensing carbonic anhydrase can2 from the pathogenic fungus cryptococcus neoformans
Author: c. schlicker, r. a. hall, d. vullo, s. middelhaufe, m. gertz, c. t. supuran, f. a. muehlschlegel, c. steegborn
Keywords: lyase, inhibition, sulfonamide, cryptococcus neoformans
- 2w3q.pdb.
lyase 14-nov-08 2w3q
Cl Zn
Title: structure and inhibition of the co2-sensing carbonic anhydrase can2 from the pathogenic fungus cryptococcus neoformans
Author: c. schlicker, r. a. hall, d. vullo, s. middelhaufe, m. gertz, c. t. supuran, f. a. muehlschlegel, c. steegborn
Keywords: lyase, inhibition, sulfonamide, cryptococcus neoformans
- 2w46.pdb.
hydrolase 21-nov-08 2w46
Na Ca
Title: cbm35 from cellvibrio japonicus abf62
Author: c. montainer, a. lammerts van bueren, c. dumon, j. e. flint, m. a. correia, j. a. prates, s. firbank, r. j. lewis, g. g. grondin, m. g. ghinet, t. m. gloster, c. herve, j. p. knox, b. g. talbot, j. p. turkenburg, j. kerovuo, r. brzezinski, c. m. g. a. fontes, g. j. davies, a. b. boraston , h. j. gilbert
Keywords: carbohydrate binding module, hydrolase
- 2w47.pdb.
hydrolase 21-nov-08 2w47
Ca
Title: clostridium thermocellum cbm35 in complex with delta-4,5- anhydrogalacturonic acid
Author: c. montainer, a. lammerts van bueren, c. dumon, j. e. flint, m. a. correia, j. a. prates, s. firbank, r. j. lewis, g. g. grondin, m. g. ghinet, t. m. gloster, c. herve, j. p. knox, b. g. talbot, j. p. turkenburg, j. kerovuo, r. brzezinski, c. m. g. a. fontes, g. j. davies, a. b. boraston , h. j. gilbert
Keywords: carbohydrate binding module, anhydrogalacturonic acid hydrolase
- 2w62.pdb.
transferase 16-dec-08 2w62
Title: saccharomyces cerevisiae gas2p in complex with laminaripentaose
Author: a. w. schuettelkopf, r. hurtado-guerrero, d. m. f. van aalten
Keywords: glycoprotein, cell membrane, fungal cell wall, transglycosylation, glucan, membrane, gpi-anchor, lipoprotein
- 2w63.pdb.
transferase 16-dec-08 2w63
Title: saccharomyces cerevisiae gas2p in complex with laminaritriose and laminaritetraose
Author: a. w. schuettelkopf, r. hurtado-guerrero, d. m. f. van aalten
Keywords: cell membrane, fungal cell wall, transglycosylation, glucan, membrane, gpi-anchor, lipoprotein, transferase
- 2w7a.pdb.
rna-binding protein 22-dec-08 2w7a
Se
Title: structure of the human line-1 orf1p central domain
Author: e. khazina, o. weichenrieder
- 2w7t.pdb.
ligase 30-dec-08 2w7t
Cl
Title: trypanosoma brucei ctps - glutaminase domain with bound acivicin
Author: m. welin, m. moche, c. h. arrowsmith, h. berglund, c. bountra, r. collins, l. g. dahlgren, a. m. edwards, s. flodin, a. flores, s. graslund, m. hammarstrom, a. johansson, i. johansson, t. karlberg, t. kotenyova, l. lehtio, m. e. nilsson, t. nyman, c. persson, j. sagemark, h. schueler, m. i. siponen, a. g. thorsell, l. tresaugues, s. van den berg, j. weigelt, m. wikstrom, m. wisniewska, p. nordlund, structural genomics consortium
Keywords: trypsanosoma brucei, ctps, ligase, acivicin, ctp synthetase
- 2w82.pdb.
replication inhibitor 08-jan-09 2w82
Title: the structure of arda
Author: s. a. mcmahon, g. a. roberts, l. g. carter, l. p. cooper, h. liu, j. h. white, k. a. johnson, b. sanghvi, m. oke, m. d. walkinshaw, g. blakely, j. h. naismith, d. t. f. dryden
Keywords: replication inhibitor
- 2w87.pdb.
hydrolase 14-jan-09 2w87
Ca
Title: xyl-cbm35 in complex with glucuronic acid containing disaccharide.
Author: c. montainer, a. l. v. bueren, c. dumon, j. e. flint, m. a. correia, j. a. prates, s. j. firbank, r. j. lewis, g. g. grondin, m. g. ghinet, t. m. gloster, c. herve, j. p. knox, b. g. talbot, j. p. turkenburg, j. kerovuo, r. brzezinski, c. m. g. a. fontes, g. j. davies, a. b. boraston, h. j. gilbert
Keywords: carbohydrate protein binding, xylan, cmb35, glucuronic acid, hydrolase
- 2w8j.pdb.
transferase 16-jan-09 2w8j
Title: spt with plp-ser
Author: l. s. carter, m. c. c. raman, k. a. johnson, d. j. campopiano, j. h. naismith
- 2w8k.pdb.
transferase/dna 16-jan-09 2w8k
Mg
Title: y-family dna polymerase dpo4 bypassing n2-naphthyl-guanine adduct in syn orientation
Author: r. l. eoff, h. zhang, m. egli, f. p. guengerich
Keywords: transferase/dna
- 2w8l.pdb.
transferase/dna 16-jan-09 2w8l
Mg
Title: y-family dna polymerase dpo4 bypassing n2-naphthyl-guanine adduct in anti orientation
Author: r. l. eoff, h. zhang, m. egli, f. p. guengerich
Keywords: transferase/dna
- 2w8t.pdb.
transferase 19-jan-09 2w8t
Title: spt with plp, n100c
Author: m. c. c. raman, k. a. johnson, d. j. campopiano, j. h. naismith
- 2w8u.pdb.
transferase 19-jan-09 2w8u
Title: spt with plp, n100y
Author: m. c. c. raman, k. a. johnson, d. j. campopiano, j. h. naismith
- 2w8v.pdb.
transferase 19-jan-09 2w8v
Title: spt with plp, n100w
Author: m. c. c. raman, k. a. johnson, d. j. campopiano, j. h. naismith
- 2w8w.pdb.
transferase 19-jan-09 2w8w
Title: n100y spt with plp-ser
Author: m. c. c. raman, k. a. johnson, d. j. campopiano, j. h. naismith
- 2w91.pdb.
hydrolase 21-jan-09 2w91
Title: structure of a streptococcus pneumoniae family 85 glycoside hydrolase, endo-d.
Author: d. w. abbott, m. s. macauley, d. j. vocadlo, a. b. boraston
Keywords: n-glycan, secreted, oxazoline, nag-thiazoline, substrate-participation, enzyme mechanism, anchimeric assistance
- 2w92.pdb.
hydrolase 21-jan-09 2w92
Title: structure of a streptococcus pneumoniae family 85 glycoside hydrolase, endo-d, in complex with nag-thiazoline.
Author: d. w. abbott, m. s. macauley, d. j. vocadlo, a. b. boraston
Keywords: nag-thiazoline, anchimeric assistance, n-glycan, substrate-participation, oxazoline, enzyme mechanism.
- 2z2f.pdb.
hydrolase 21-may-07 2z2f
Na
Title: x-ray crystal structure of bovine stomach lysozyme
Author: d. akieda, y. nonaka, n. watanabe, i. tanaka, m. kamiya, t. aizawa, k. nitta, m. demura, k. kawano
Keywords: stomach lysozyme, 1,4-beta-n-acetylmuramidase c, bacteriolytic enzyme, hydrolase
- 2zgc.pdb.
hydrolase 21-jan-08 2zgc
Title: crystal structure of active human granzyme m
Author: l. f. wu, l. wang, g. q. hua, k. liu, y. j. zhai, f. sun, z. s. fan
Keywords: cytolysis, glycoprotein, hydrolase, secreted, zymogen
- 2zgh.pdb.
hydrolase 22-jan-08 2zgh
Title: crystal structure of active granzyme m bound to its product
Author: l. f. wu, l. wang, g. q. hua, k. liu, y. j. zhai, f. sun, z. s. fan
Keywords: synthesized peptide, cytolysis, glycoprotein, hydrolase, protease, secreted, zymogen
- 2zgj.pdb.
hydrolase 22-jan-08 2zgj
Title: crystal structure of d86n-gzmm complexed with its optimal synthesized substrate
Author: l. f. wu, l. wang, g. q. hua, k. liu, y. j. zhai, f. sun, z. s. fan
Keywords: synthesized peptide, cytolysis, glycoprotein, hydrolase, secreted, zymogen
- 2zm1.pdb.
transferase 10-apr-08 2zm1
Cl
Title: crystal structure of imidazo pyrazin 1 bound to the kinase domain of human lck, (auto-phosphorylated on tyr394)
Author: e. tsuji
Keywords: nucleotide- binding, palmitate, phosphoprotein, proto-oncogene, sh2 domain, sh3 domain, transferase
- 2zm4.pdb.
transferase 11-apr-08 2zm4
Cl
Title: crystal structure of imidazo quinoxaline 1 bound to the kinase domain of human lck, activated form (auto- phosphorylated on tyr394)
Author: e. tsuji
Keywords: nucleotide- binding, palmitate, phosphoprotein, proto-oncogene, sh2 domain, sh3 domain, transferase
- 2znw.pdb.
immune system/hydrolase 02-may-08 2znw
Title: crystal structure of scfv10 in complex with hen egg lysozyme
Author: m. e. desantis, m. acchione, m. li, r. walter, a. wlodawer, s. smith- gill
Keywords: lysozyme, allergen, antimicrobial, bacteriolytic enzyme, glycosidase, hydrolase, immune system/hydrolase complex
- 2znx.pdb.
immune system/hydrolase 02-may-08 2znx
F
Title: 5-fluorotryptophan incorporated scfv10 complexed to hen egg lysozyme
Author: m. e. desantis, m. acchione, m. li, r. walter, a. wlodawer, s. smith- gill
Keywords: 5-fluorotryptophan, 19f, single chain fv, lysozyme, allergen, antimicrobial, bacteriolytic enzyme, glycosidase, hydrolase, immune system/hydrolase complex
- 2zoe.pdb.
toxin 09-may-08 2zoe
Se
Title: ha3 subcomponent of clostridium botulinum type c progenitor toxin, complex with n-acetylneuramic acid
Author: t. nakamura, m. kotani, t. tonozuka, a. ide, k. oguma, a. nishikawa
Keywords: hemagglutinin, jelly roll
- 2zos.pdb.
hydrolase 05-jun-08 2zos
Se
Title: crystal structure of mannosyl-3-phosphoglycerate phosphatase from pyrococcus horikoshii
Author: t. kawamura, n. watanabe, i. tanaka
Keywords: phosphatase, mannosylglycerate, cytoplasm, hydrolase, magnesium
- 2zs6.pdb.
toxin 02-sep-08 2zs6
Title: ha3 subcomponent of botulinum type c progenitor toxin
Author: t. nakamura, t. tonozuka, m. kotani, k. oguma, a. nishikawa
Keywords: hemagglutinin, botulinum toxin
- 2zwh.pdb.
contractile protein 05-dec-08 2zwh
Ca
(fiber diffraction)
Title: model for the f-actin structure
Author: t. oda, m. iwasa, t. aihara, y. maeda, a. narita
Keywords: g-actin, cytoskelton, fiber-diffraction, contractile protein, acetylation, atp-binding, cytoplasm, cytoskeleton, methylation, muscle protein, nucleotide- binding, phosphoprotein
- 2zxs.pdb.
hydrolase 06-jan-09 2zxs
Cl Na
Title: effect of glycine-amide (glyad) on lysozyme
Author: l. ito, k. shiraki, h. yamaguchi
Keywords: hydrolase, glycosidase, bacteriolytic enzyme, glycine-amide, allergen, antimicrobial
- 2zy2.pdb.
lyase 13-jan-09 2zy2
Title: dodecameric l-aspartate beta-decarboxylase
Author: h. -j. chen, t. -p. ko, c. -y. lee, n. -c. wang, a. h. -j. wang
Keywords: aminotransferase, lyase
- 2zy3.pdb.
lyase 13-jan-09 2zy3
Title: dodecameric l-aspartate beta-decarboxylase
Author: h. -j. chen, t. -p. ko, c. -y. lee, n. -c. wang, a. h. -j. wang
Keywords: aminotransferase, lyase
- 2zy4.pdb.
lyase 13-jan-09 2zy4
Cl
Title: dodecameric l-aspartate beta-decarboxylase
Author: h. -j. chen, t. -p. ko, c. -y. lee, n. -c. wang, a. h. -j. wang
Keywords: aminotransferase, lyase
- 2zy5.pdb.
lyase 13-jan-09 2zy5
Title: r487a mutant of l-aspartate beta-decarboxylase
Author: h. -j. chen, t. -p. ko, c. -y. lee, n. -c. wang, a. h. -j. wang
Keywords: aminotransferase, lyase
- 3b96.pdb.
oxidoreductase 02-nov-07 3b96
Title: structural basis for substrate fatty-acyl chain specificity: crystal structure of human very-long-chain acyl-coa dehydrogenase
Author: r. p. mcandrew, y. wang, a. w. mohsen, m. he, j. vockley, j. j. kim
Keywords: lipid metabolism, mitochondrion, oxidoreductase, polymorphism, transit peptide, ubl conjugation
- 3beh.pdb.
membrane protein 18-nov-07 3beh
K
Title: structure of a bacterial cyclic nucleotide regulated ion channel
Author: g. m. clayton, j. h. morais-cabral
- 3bos.pdb.
hydrolase regulator 17-dec-07 3bos
Cl Mg Na Se
Title: crystal structure of putative dna replication regulator hda (yp_927791.1) from shewanella amazonensis sb2b at 1.75 a resolution
Author: joint center for structural genomics (jcsg)
Keywords: putative dna replication regulator hda, structural genomics, joint center for structural genomics, jcsg, protein structure initiative, psi-2, hydrolase regulator
- 3bus.pdb.
transferase 03-jan-08 3bus
Se
Title: crystal structure of rebm
Author: j. g. mccoy, s. singh, c. a. bingman, j. s. thorson, g. n. phillips
Keywords: methyltransferase, transferase
- 3bvg.pdb.
toxin 07-jan-08 3bvg
Zn
Title: manipulating the coupled folding and binding process drives affinity maturation in a protein-protein complex
Author: s. cho, j. s. eric
Keywords: secreted, superantigen, toxin
- 3bvo.pdb.
chaperone 07-jan-08 3bvo
Zn Se
Title: crystal structure of human co-chaperone protein hscb
Author: e. bitto, c. a. bingman, j. g. mccoy, g. e. wesenberg, g. n. phillips jr. , center for eukaryotic structural genomics (cesg)
Keywords: structural genomics medical relevance, protein structure initiative, psi-2, center for eukaryotic structural genomics, cesg, mitochondrion, transit peptide
- 3bxm.pdb.
hydrolase 14-jan-08 3bxm
Cl Zn Ca
Title: structure of an inactive mutant of human glutamate carboxypeptidase ii [gcpii(e424a)] in complex with n- acetyl-asp-glu (naag)
Author: j. lubkowski, c. barinka
Keywords: transmembrane, zinc
- 3byc.pdb.
hydrolase 15-jan-08 3byc
He Hg D Ca
Title: joint neutron and x-ray structure of diisopropyl fluorophosphatase. deuterium occupancies are 1-q, where q is occupancy of h
Author: m. -m. blum, m. mustyakimov, h. ruterjans, b. p. schoenborn, p. langan, j. c. -h. chen
Keywords: phosphotriesterase, hydrolase
- 3c1p.pdb.
peptide nucleic acid 23-jan-08 3c1p
Title: crystal structure of an alternating d-alanyl, l-homoalanyl pna
Author: j. a. cuesta-seijo, g. m. sheldrick, j. zhang, u. diederichsen
Keywords: peptide nucleic acid, pna, alanyl, homoalanyl, de novo protein
- 3c22.pdb.
immune system, sugar binding protein 24-jan-08 3c22
Mg Ca
Title: crystal structure of the carbohydrate recognition domain of human langerin
Author: m. thepaut
Keywords: coiled coil, glycoprotein, membrane, signal-anchor, transmembrane, immune system, sugar binding protein
- 3c38.pdb.
signaling protein, transferase 27-jan-08 3c38
Title: crystal structure of the periplasmic domain of vibrio cholerae luxq
Author: b. slama, w. hendrickson
Keywords: quorum sensing, histidine kinase, hydrolase, inner membrane, membrane, phosphoprotein, protein phosphatase, transferase, transmembrane, two- component regulatory system, signaling protein
- 3caf.pdb.
transferase 19-feb-08 3caf
Title: crystal structure of hfgfr2 d2 domain
Author: f. guo, r. dakshinamurthy, k. m. kathir, s. k. k. thallapuranam, j. sakon
Keywords: lacrimo-auriculo-dento-digital syndrome, membrane, nucleotide-binding, phosphoprotein, polymorphism, receptor, secreted, transferase, transmembrane, tyrosine-protein kinase
- 3cg8.pdb.
oxidoreductase 05-mar-08 3cg8
Cu
Title: laccase from streptomyces coelicolor
Author: t. skalova, j. dohnalek, l. h. ostergaard, p. r. ostergaard, p. kolenko, j. duskova, j. hasek
Keywords: oxidoreductase, multicopper blue protein
- 3ckf.pdb.
membrane protein 14-mar-08 3ckf
Title: the crystal structure of ospa deletion mutant
Author: k. makabe, s. koide
Keywords: membrane protein
- 3ckg.pdb.
membrane protein 14-mar-08 3ckg
Mg
Title: the crystal structure of ospa deletion mutant
Author: k. makabe, s. koide
Keywords: membrane protein
- 3daf.pdb.
oxidoreductase 29-may-08 3daf
Fe
Title: the crystal structure of [fe]-hydrogenase holoenzyme (hmd) from methanocaldococcus jannaschii cocrystallized with cyanide
Author: o. pilak, e. warkentin, s. shima, r. k. thauer, u. ermler
Keywords: helix bundle, methanogenesis, one-carbon metabolism, oxidoreductase
- 3dag.pdb.
oxidoreductase 29-may-08 3dag
Fe
Title: the crystal structure of [fe]-hydrogenase holoenzyme (hmd) from methanocaldococcus jannaschii
Author: o. pilak, e. warkentin, s. shima, r. k. thauer, u. ermler
Keywords: helix bundle, methanogenesis, one-carbon metabolism, oxidoreductase
- 3dds.pdb.
transferase 06-jun-08 3dds
Title: crystal structure of glycogen phosphorylase complexed with an anthranilimide based inhibitor gsk261
Author: r. t. nolte
Keywords: phosphoprotein, polymorphism, pyridoxal phosphate, transferase
- 3ddw.pdb.
transferase 06-jun-08 3ddw
Cl
Title: crystal structure of glycogen phosphorylase complexed with an anthranilimide based inhibitor gsk055
Author: r. t. nolte
Keywords: polymorphism, pyridoxal phosphate, transferase
- 3dg8.pdb.
oxidoreductase, transferase 13-jun-08 3dg8
Title: quadruple mutant (n51i+c59r+s108n+i164l) plasmodium falciparum dihydrofolate reductase-thymidylate synthase (pfdhfr-ts) complexed with rjf670, nadph, and dump
Author: t. dasgupta, p. chitnumsub, c. maneeruttanarungroj, s. kamchonwongpaisan, s. nichols, t. m. lyons, j. tirado-rives, w. l. jorgensen, y. yuthavong, k. s. anderson
Keywords: methyltransferase, oxidoreductase, transferase
- 3dga.pdb.
oxidoreductase, transferase 13-jun-08 3dga
Cl F
Title: wild-type plasmodium falciparum dihydrofolate reductase- thymidylate synthase (pfdhfr-ts) complexed with rjf01302, nadph, and dump
Author: t. dasgupta, p. chitnumsub, c. maneeruttanarungroj, s. kamchonwongpaisan, s. nichols, t. m. lyons, j. tirado-rives, w. l. jorgensen, y. yuthavong, k. s. anderson
Keywords: methyltransferase, oxidoreductase, transferase
- 3dhs.pdb.
hydrolase, rna 18-jun-08 3dhs
Os
Title: mapping metal-binding sites in the catalytic domain of bacterial rnase p rna
Author: n. r. pace, a. v. kazantsev, a. a. krivenko
Keywords: rna processing, hydrolase, rna
- 3di2.pdb.
cytokine/cytokine receptor 19-jun-08 3di2
Title: crystal structure of the complex of human interleukin-7 with unglycosylated human interleukin-7 receptor alpha ectodomain
Author: c. a. mcelroy, j. a. dohm, s. t. r. walsh
Keywords: cytokine/cytokine receptor complex
- 3di3.pdb.
cytokine/cytokine receptor 19-jun-08 3di3
Title: crystal structure of the complex of human interleukin-7 with glycosylated human interleukin-7 receptor alpha ectodomain
Author: c. a. mcelroy, j. a. dohm, s. t. r. walsh
Keywords: cytokine/cytokine receptor complex
- 3dmv.pdb.
hydrolase 01-jul-08 3dmv
Cl
Title: free of ligand binding in the hydrophobic cavity of t4 lysozyme l99a mutant
Author: l. liu, b. w. matthews
Keywords: halogen bond, cavity, halogenated benzene, antimicrobial, bacteriolytic enzyme, glycosidase, hydrolase
- 3dmx.pdb.
hydrolase 01-jul-08 3dmx
Cl
Title: benzene binding in the hydrophobic cavity of t4 lysozyme l99a mutant
Author: l. liu, b. w. matthews
Keywords: halogen bond, hydrophobic cavity, halogenated benzene, antimicrobial, bacteriolytic enzyme, glycosidase, hydrolase
- 3dmz.pdb.
hydrolase 01-jul-08 3dmz
Cl F
Title: hexafluorobenzene binding in the hydrophobic cavity of t4 lysozyme l99a mutant
Author: l. liu, b. w. matthews
Keywords: halogen bond, hydrophobic cavity, halogenated benzene, antimicrobial, bacteriolytic enzyme, glycosidase, hydrolase
- 3dn0.pdb.
hydrolase 01-jul-08 3dn0
Cl F
Title: pentafluorobenzene binding in the hydrophobic cavity of t4 lysozyme l99a mutant
Author: l. liu, b. w. matthews
Keywords: halogen bond, hydrophobic cavity, halogenated benzene, antimicrobial, bacteriolytic enzyme, glycosidase, hydrolase
- 3dn1.pdb.
hydrolase 01-jul-08 3dn1
Cl F
Title: chloropentafluorobenzene binding in the hydrophobic cavity of t4 lysozyme l99a mutant
Author: l. liu, b. w. matthews
Keywords: halogen bond, hydrophobic cavity, halogenated benzene, antimicrobial, bacteriolytic enzyme, glycosidase, hydrolase
- 3dn2.pdb.
hydrolase 01-jul-08 3dn2
F Br
Title: bromopentafluorobenzene binding in the hydrophobic cavity of t4 lysozyme l99a mutant
Author: l. liu, b. w. matthews
Keywords: halogen bond, hydrophobic cavity, halogenated benzene, antimicrobial, bacteriolytic enzyme, glycosidase, hydrolase
- 3dn3.pdb.
hydrolase 01-jul-08 3dn3
F I
Title: iodopentafluorobenzene binding in the hydrophobic cavity of t4 lysozyme l99a mutant
Author: l. liu, b. w. matthews
Keywords: halogen bond, hydrophobic cavity, halogenated benzene, antimicrobial, bacteriolytic enzyme, glycosidase, hydrolase
- 3dn4.pdb.
hydrolase 01-jul-08 3dn4
I
Title: iodobenzene binding in the hydrophobic cavity of t4 lysozyme l99a mutant
Author: l. liu, b. w. matthews
Keywords: halogen bond, hydrophobic cavity, halogenated benzene, antimicrobial, bacteriolytic enzyme, glycosidase, hydrolase
- 3dn6.pdb.
hydrolase 01-jul-08 3dn6
Cl F
Title: 1,3,5-trifluoro-2,4,6-trichlorobenzene binding in the hydrophobic cavity of t4 lysozyme l99a mutant
Author: l. liu, b. w. matthews
Keywords: halogen bond, hydrophobic cavity, halogenated benzene, antimicrobial, bacteriolytic enzyme, glycosidase, hydrolase
- 3dn8.pdb.
hydrolase 01-jul-08 3dn8
Cl F I Se
Title: iodopentafluorobenzene binding in the hydrophobic cavity of t4 lysozyme l99a mutant (seleno version)
Author: l. liu, b. w. matthews
Keywords: halogen bond, hydrophobic cavity, halogenated benzene, antimicrobial, bacteriolytic enzyme, glycosidase, hydrolase
- 3dna.pdb.
hydrolase 01-jul-08 3dna
Cl I Se
Title: iodobenzene binding in the hydrophobic cavity of t4 lysozyme l99a mutant (seleno version)
Author: l. liu, b. w. matthews
Keywords: halogen bond, hydrophobic cavity, halogenated benzene, antimicrobial, bacteriolytic enzyme, glycosidase, hydrolase
- 3dnt.pdb.
transferase 02-jul-08 3dnt
Mg Se
Title: structures of mdt proteins
Author: m. a. schumacher
Keywords: persistence, multidrug resistance, tolerance, transferase
- 3dnu.pdb.
unknown function 02-jul-08 3dnu
Cl Se
Title: structure of mdt protein
Author: m. a. schumacher
Keywords: mdt, multidrug resistance, unknown function
- 3dnv.pdb.
transcription/dna 02-jul-08 3dnv
Se
Title: mdt protein
Author: m. a. schumacher
Keywords: mdt, dna-binding, repressor, transcription, transcription regulation, transcription/dna complex
- 3dnw.pdb.
transcription/dna 02-jul-08 3dnw
Se
Title: structure of mdt protein
Author: m. a. schumacher
Keywords: persistence, dna-binding, repressor, transcription, transcription regulation, transcription/dna complex
- 3dr9.pdb.
oxidoreductase 10-jul-08 3dr9
Fe
Title: increased distal histidine conformational flexibility in the deoxy form of dehaloperoxidase from amphitrite ornata
Author: x. chen, v. s. de serrano, l. betts, s. franzen
Keywords: dhp, heme peroxidase, globin-like, globin, heme protein, heme, oxygen transport, peroxidase, transport, oxidoreductase
- 3dx5.pdb.
lyase 23-jul-08 3dx5
Cl Mn Se
Title: crystal structure of the probable 3-dhs dehydratase asbf involved in the petrobactin synthesis from bacillus anthracis
Author: y. kim, n. maltseva, l. stols, w. eschenfeldt, b. pfleger, d. h. sherman, a. joachimiak, midwest center for structural genomics (mcsg)
Keywords: petrobactin synthesis, asb locus, structural genomics, psi-2, protein structure initiative, midwest center for structural genomics, mcsg, unknown function, lyase
- 3dx6.pdb.
immune system 23-jul-08 3dx6
Title: crystal structure of b*4402 presenting a 10mer ebv epitope
Author: j. k. archbold, w. a. macdonald, s. gras, l. k. ely, j. j. miles, m. j. bell, r. m. brennan, t. beddoe, m. c. wilce, c. s. clements, a. w. purcell, j. mccluskey, s. r. burrows, j. rossjohn
Keywords: glycoprotein, glycation, host-virus interaction, immune response, membrane, mhc i, polymorphism, transmembrane, ubl conjugation, pyrrolidone carboxylic acid, disease mutation, immune system
- 3dx7.pdb.
immune system 23-jul-08 3dx7
Title: crystal structure of hla-b*4403 presenting 10mer ebv antigen
Author: j. k. archbold, l. k. ely, j. rossjohn
Keywords: glycoprotein, glycation, host-virus interaction, immune response, membrane, mhc i, polymorphism, transmembrane, ubl conjugation, pyrrolidone carboxylic acid, disease mutation, immune system
- 3dx8.pdb.
immune system 23-jul-08 3dx8
Title: crystal structure of b*4405 presenting a 10mer ebv epitope
Author: j. k. archbold, l. k. ely, j. rossjohn
Keywords: glycoprotein, glycation, host-virus interaction, immune response, membrane, mhc i, polymorphism, transmembrane, ubl conjugation, pyrrolidone carboxylic acid, disease mutation, immune system
- 3dx9.pdb.
immune system 24-jul-08 3dx9
Title: crystal structure of the dm1 tcr at 2.75a
Author: j. k. archbold, w. a. macdonald, s. gras, j. rossjohn
Keywords: glycoprotein, glycation, host-virus interaction, immune response, membrane, immune system
- 3dxa.pdb.
immune system 23-jul-08 3dxa
Title: crystal structure of the dm1 tcr in complex with hla-b*4405 and decamer ebv antigen
Author: j. k. archbold, w. a. macdonald, s. gras, j. rossjohn
Keywords: glycoprotein, glycation, host-virus interaction, immune response, membrane, mhc i, polymorphism, transmembrane, ubl conjugation, pyrrolidone carboxylic acid, disease mutation, immune system
- 3dyj.pdb.
structural protein 28-jul-08 3dyj
Se
Title: crystal structure a talin rod fragment
Author: a. r. gingras, m. g. joyce, d. r. critchley, j. emsley
Keywords: helix bundles, cytoskeletal protein, integrin-bindin site, ibs2, cell membrane, cell projection, cytoplasm, cytoskeleton, membrane, phosphoprotein, structural protein
- 3dyr.pdb.
electron transport 28-jul-08 3dyr
Title: crystal structure of e. coli thioredoxin mutant i76t in its oxidized form
Author: g. ren, j. c. a. bardwell, z. xu
Keywords: electron transport, host-virus interaction, redox-active center, transport
- 3e1z.pdb.
hydrolase inhibitor/hydrolase 05-aug-08 3e1z
Zn
Title: crystal structure of the parasite protesase inhibitor chagasin in complex with papain
Author: i. redzynia, g. bujacz, a. bujacz, a. ljunggren, m. abrahamson, m. jaskolski
Keywords: hydrolase inhibitor/hydrolase complex
- 3e53.pdb.
ligase 13-aug-08 3e53
Se
Title: crystal structure of n-terminal domain of a fatty acyl amp ligase faal28 from mycobacterium tuberculosis
Author: a. goyal, e. rajakumara, m. yousuf, r. sankaranarayanan
Keywords: fadd28, mycobacterium tuberculosis, crystal structure, ligase
- 3e9k.pdb.
hydrolase 22-aug-08 3e9k
Title: crystal structure of homo sapiens kynureninase-3- hydroxyhippuric acid inhibitor complex
Author: s. lima, s. kumar, v. gawandi, c. momany, r. s. phillips
Keywords: pyridine nucleotide biosynthesis, pyridoxal phosphate
- 3e9u.pdb.
membrane protein 23-aug-08 3e9u
Title: crystal structure of calx cbd2 domain
Author: m. wu, l. zheng
Keywords: calx, membrane, transmembrane, membrane protein
- 3e9w.pdb.
dna 24-aug-08 3e9w
Title: x-ray crystal structure of the hexamer dcacacg:crystal grown in the presence of cobalt(iii)hexammine chloride.
Author: s. venkadesh, p. k. mandal, n. gautham
Keywords: dna
- 3ebg.pdb.
hydrolase 27-aug-08 3ebg
Mg Zn
Title: structure of the m1 alanylaminopeptidase from malaria
Author: s. mcgowan, c. j. porter, a. m. buckle, j. c. whisstock
Keywords: aminopeptidase, cytoplasm, metal-binding, metalloprotease, protease, zinc
- 3ebh.pdb.
hydrolase inhibitor 27-aug-08 3ebh
Mg Zn
Title: structure of the m1 alanylaminopeptidase from malaria complexed with bestatin
Author: s. mcgowan, c. j. porter, a. m. buckle, j. c. whisstock
Keywords: aminopeptidase, cytoplasm, metal-binding, metalloprotease, protease, zinc, hydrolase inhibitor
- 3ebi.pdb.
hydrolase inhibitor 27-aug-08 3ebi
Mg Zn
Title: structure of the m1 alanylaminopeptidase from malaria complexed with the phosphinate dipeptide analog
Author: s. mcgowan, c. j. porter, a. m. buckle, j. c. whisstock
Keywords: aminopeptidase, cytoplasm, metal-binding, metalloprotease, protease, zinc, hydrolase inhibitor
- 3ec1.pdb.
hydrolase, signaling protein 28-aug-08 3ec1
Title: structure of yqeh gtpase from geobacillus stearothermophilus (an atnos1 / atnoa1 ortholog)
Author: j. sudhamsu, b. r. crane
Keywords: atnos1, atnoa1, gtpase, trap, pvhl, hydrolase, signaling protein
- 3ek5.pdb.
transferase 18-sep-08 3ek5
Title: unique gtp-binding pocket and allostery of ump kinase from a gram-negative phytopathogen bacterium
Author: j. -l. tu, k. -h. chin, a. h. -j. wang, s. -h. chou
Keywords: umpk crystal structure, unique gtp binding site, allosteric regulation, atp-binding, cytoplasm, kinase, nucleotide-binding, pyrimidine biosynthesis, transferase
- 3ek6.pdb.
transferase 18-sep-08 3ek6
Title: unique gtp-binding pocket and allostery of ump kinase from a gram-negative phytopathogen bacterium
Author: j. -l. tu, k. -h. chin, a. h. -j. wang, s. -h. chou
Keywords: umpk crystal structure, unique gtp binding site, allosteric regulation, atp-binding, cytoplasm, kinase, nucleotide-binding, pyrimidine biosynthesis, transferase
- 3eq5.pdb.
signaling protein 30-sep-08 3eq5
Title: crystal structure of fragment 137 to 238 of the human ski- like protein
Author: l. tresaugues, m. wisniewska, j. andersson, c. h. arrowsmith, h. berglund, c. bountra, r. collins, l. g. dahlgren, a. m. edwards, s. flodin, a. flores, s. graslund, m. hammarstrom, a. johansson, i. johansson, t. karlberg, t. kotenyova, l. lehtio, m. moche, m. e. nilsson, t. nyman, k. olesen, c. persson, j. sagemark, h. schueler, a. g. thorsell, s. van den berg, m. welin, m. wikstrom, j. weigelt, p. nordlund, structural genomics consortium (sgc)
Keywords: ski-like protein,sno,receptor signalling, tgf-beta, alternative splicing, coiled coil, polymorphism, signaling protein, structural genomics, sgc stockholm, structural genomics consortium, sgc
- 3etr.pdb.
oxidoreductase 08-oct-08 3etr
Mo Fe Ca
Title: crystal structure of xanthine oxidase in complex with lumazine
Author: j. m. pauff, h. cao, r. hille
Keywords: enzyme catalysis, substrate orientation, 2fe-2s, fad, flavoprotein, iron, iron-sulfur, metal-binding, molybdenum, nad, oxidoreductase, peroxisome
- 3eub.pdb.
oxidoreductase 09-oct-08 3eub
Mo Fe
Title: crystal structure of desulfo-xanthine oxidase with xanthine
Author: j. m. pauff, h. cao, r. hille
Keywords: desulfo, substrate orientation, xanthine, 2fe-2s, fad, flavoprotein, iron, iron-sulfur, metal-binding, molybdenum, nad, oxidoreductase, peroxisome
- 3f2q.pdb.
rna 30-oct-08 3f2q
Mg K
Title: crystal structure of the fmn riboswitch bound to fmn
Author: a. a. serganov, l. huang
Keywords: transcription, rna
- 3f2t.pdb.
rna 30-oct-08 3f2t
Mg K Ir
Title: crystal structure of the fmn riboswitch bound to fmn, iridium hexamine soak.
Author: a. a. serganov, l. huang
Keywords: transcription, rna
- 3f2w.pdb.
rna 30-oct-08 3f2w
Mg Ba
Title: crystal structure of the fmn riboswitch bound to fmn, ba2+ soak.
Author: a. a. serganov, l. huang
Keywords: riboswitch, transcription, barium, rna
- 3f2x.pdb.
rna 30-oct-08 3f2x
Mg Cs
Title: crystal structure of the fmn riboswitch bound to fmn, cs+ soak.
Author: a. a. serganov, l. huang
Keywords: riboswitch, transcription, cesium, rna
- 3f2y.pdb.
rna 30-oct-08 3f2y
Mg Mn K
Title: crystal structure of the fmn riboswitch bound to fmn, mn2+ soak.
Author: a. a. serganov, l. huang
Keywords: riboswitch, transcription, manganese, rna
- 3f30.pdb.
rna 30-oct-08 3f30
Co Mg K
Title: crystal structure of the fmn riboswitch bound to fmn, cobalt hexammine soak.
Author: a. a. serganov, l. huang
Keywords: riboswitch, transcription, cobalt hexamine, rna
- 3f4e.pdb.
rna 31-oct-08 3f4e
Mg K
Title: crystal structure of the fmn riboswitch bound to fmn, split rna.
Author: a. a. serganov, l. huang
Keywords: riboswitch, transcription, rna
- 3f4g.pdb.
rna 31-oct-08 3f4g
Mg K
Title: crystal structure of the fmn riboswitch bound to riboflavin.
Author: a. a. serganov, l. huang
Keywords: fmn, riboswitch, transcription, rna
- 3f4h.pdb.
rna 31-oct-08 3f4h
Mg K
Title: crystal structure of the fmn riboswitch bound to roseoflavin
Author: a. a. serganov, l. huang
Keywords: fmn, riboswitch, transcription, rna
- 3f5h.pdb.
protein binding 03-nov-08 3f5h
Na
Title: crystal structure of fused docking domains from pikaiii and pikaiv of the pikromycin polyketide synthase
Author: t. j. buchholz, t. w. geders, f. e. bartley, k. a. reynolds, j. l. smith, d. h. sherman
Keywords: polyketide synthase, pikromycin, h2-t2, protein binding
- 3f6k.pdb.
signaling protein 06-nov-08 3f6k
Title: crystal structure of the vps10p domain of human sortilin/nts3 in complex with neurotensin
Author: e. m. quistgaard, p. madsen, m. k. groftehauge, p. nissen, c. m. petersen, s. thirup
Keywords: golgi apparatus, lysosome, membrane, phosphoprotein, receptor, transmembrane, transport, cytoplasmic vesicle, secreted, signaling protein
- 3f6q.pdb.
signaling protein/signaling protein 06-nov-08 3f6q
I Zn
Title: crystal structure of integrin-linked kinase ankyrin repeat domain in complex with pinch1 lim1 domain
Author: b. p. chiswell, d. a. calderwood, t. j. boggon
Keywords: serine/threonine- protein kinase, transferase, acetylation, lim domain, metal- binding, zinc, transferase/metal binding protein complex, signaling protein/signaling protein complex
- 3fa1.pdb.
dna 14-nov-08 3fa1
Te Se
Title: crystal structure of tellurium derivatized dna
Author: j. sheng, m. tatsuya, a. e. hassan, z. huang
- 3fa3.pdb.
lyase 14-nov-08 3fa3
F Mn
Title: crystal structure of 2,3-dimethylmalate lyase, a pep mutase/isocitrate lyase superfamily member, trigonal crystal form
Author: b. c. narayanan, o. herzberg
Keywords: helix swapping, lyase
- 3fa4.pdb.
lyase 14-nov-08 3fa4
Mg
Title: crystal structure of 2,3-dimethylmalate lyase, a pep mutase/isocitrate lyase superfamily member, triclinic crystal form
Author: b. c. narayanan, o. herzberg
Keywords: helix swapping, lyase
- 3faa.pdb.
transferase 16-nov-08 3faa
F
Title: crystal structure of tgfbri complexed with a 2- aminoimidazole inhibitor
Author: p. a. boriack-sjodin, c. fitch
Keywords: phosphoprotein, polymorphism, receptor, serine/threonine-protein kinase, transferase, transmembrane
- 3fcr.pdb.
transferase 22-nov-08 3fcr
Se
Title: crystal structure of putative aminotransferase (yp_614685.1) from silicibacter sp. tm1040 at 1.80 a resolution
Author: joint center for structural genomics (jcsg)
Keywords: putative aminotransferase, structural genomics, joint center for structural genomics, jcsg, protein structure initiative, psi-2, aminotransferase, pyridoxal phosphate, transferase
- 3fe7.pdb.
cell cycle 28-nov-08 3fe7
Title: crystal structure of hdmx bound to the p53-peptidomimetic ac-phe-met-aib-pmp-trp-glu-ac3c-leu-nh2 at 1.35a
Author: j. kallen
Keywords: hdm4,human mdm4, human mdmx, protein-protein interaction, p53, cell cycle, alternative splicing, metal- binding, nucleus, polymorphism, zinc, zinc-finger
- 3fea.pdb.
cell cycle 28-nov-08 3fea
Cl
Title: crystal structure of hdmx bound to the p53-peptidomimetic ac-phe-met-aib-pmp-6-cl-trp-glu-ac3c-leu-nh2 at 1.33a
Author: j. kallen
Keywords: hdm4,human mdm4, human mdmx, protein-protein interaction, p53, metal-binding, nucleus, polymorphism, zinc, zinc-finger, cell cycle
- 3few.pdb.
immune system 01-dec-08 3few
Na
Title: structure and function of colicin s4, a colicin with a duplicated receptor binding domain
Author: t. arnold, d. linke, k. zeth
Keywords: cell lysis, y-ray, cell killing, immune system
- 3ffc.pdb.
immune system 03-dec-08 3ffc
Cl Na Cd
Title: crystal structure of cf34 tcr in complex with hla-b8/flr
Author: s. gras, s. r. burrows, l. kjer-nielsen, c. s. clements, y. c. liu, l. c. sullivan, a. g. brooks, a. w. purcell, j. mccluskey, j. rossjohn
Keywords: secreted, immune system
- 3ffv.pdb.
protein binding 04-dec-08 3ffv
Title: crystal structure analysis of syd
Author: r. maurus, g. d. brayer
Keywords: translocon, secyeg, syd, nanodisc, cell inner membrane, cell membrane, protein binding
- 3fl7.pdb.
transferase, signaling protein 18-dec-08 3fl7
Cl Na
Title: crystal structure of the human ephrin a2 ectodomain
Author: j. r. walker, l. yermekbayeva, a. seitova, c. butler-cole, c. bountra, j. weigelt, c. h. arrowsmith, a. m. edwards, a. bochkarev, s. dhe- paganon, structural genomics consortium (sgc)
Keywords: egf-like motif, fibronectin domain, structural genomics consortium, sgc, membrane, phosphoprotein, signaling protein
- 3fmb.pdb.
structural genomics, unknown function 19-dec-08 3fmb
Se
Title: crystal structure of dimeric protein of unknown function and ferredoxin-like fold (yp_212648.1) from bacteroides fragilis nctc 9343 at 1.85 a resolution
Author: joint center for structural genomics (jcsg)
Keywords: unknown function
- 3fmz.pdb.
transport protein 22-dec-08 3fmz
F
Title: crystal structure of retinol-binding protein 4 (rbp4) in complex with non-retinoid ligand
Author: z. wang, s. johnstone, n. p. walker
Keywords: disease mutation, retinol-binding, secreted, sensory transduction, transport, vision, vitamin a, transport protein
- 3fn2.pdb.
transferase 23-dec-08 3fn2
K Se
Title: crystal structure of a putative sensor histidine kinase domain from clostridium symbiosum atcc 14940
Author: m. e. cuff, c. tesar, l. freeman, a. joachimiak, midwest center for structural genomics (mcsg)
Keywords: sensor histidine kinase, structural genomics, psi-2, protein structure initiative, midwest center for structural genomics, mcsg, transferase
- 3fna.pdb.
isomerase 23-dec-08 3fna
Se
Title: crystal structure of the cbs pair of possible d-arabinose 5- phosphate isomerase yrbh from escherichia coli cft073
Author: m. e. cuff, l. bigelow, k. buck, a. joachimiak, midwest center for structural genomics (mcsg)
Keywords: structural genomics, d-arabinose 5-phosphate isomerase, psi-2, protein structure initiative, midwest center for structural genomics, mcsg, cbs domain, isomerase, lipopolysaccharide biosynthesis
- 3fnc.pdb.
transferase 24-dec-08 3fnc
Se
Title: crystal structure of a putative acetyltransferase from listeria innocua
Author: m. e. cuff, c. tesar, l. freeman, a. joachimiak, midwest center for structural genomics (mcsg)
Keywords: rimi, acetyltransferase, listeria innocua, structural genomics, psi-2, protein structure initiative, midwest center for structural genomics, mcsg
- 3fnl.pdb.
oxidoreductase 25-dec-08 3fnl
I Fe Ca
Title: crystal structure of the complex of buffalo lactoperoxidase with salicylhydroxamic acid at 2.48 a resolution
Author: i. a. sheikh, g. vikram, n. singh, m. sinha, a. bhushan, s. sharma, p. kaur, t. p. singh
Keywords: crystal structure, buffalo, salicylhydroxamic acid, peroxidase, oxidoreductase
- 3fnr.pdb.
transferase 26-dec-08 3fnr
Title: crystal structure of putative arginyl t-rna synthetase from campylobacter jejuni;
Author: y. patskovsky, u. ramagopal, r. toro, m. gilmore, s. chang, c. groshong, j. m. sauder, s. k. burley, s. c. almo, new york sgx research center for structural genomics (nysgxrc)
Keywords: nucleotide- binding, protein biosynthesis
- 3fog.pdb.
protein transport 30-dec-08 3fog
Na
Title: crystal structure of the px domain of sorting nexin-17 (snx17)
Author: m. wisniewska, l. tresaugues, c. h. arrowsmith, h. berglund, c. bountra, r. collins, l. g. dahlgren, a. m. edwards, s. flodin, a. flores, s. graslund, m. hammarstrom, a. johansson, i. johansson, t. karlberg, t. kotenyova, l. lehtio, m. moche, m. e. nilsson, p. nordlund, t. nyman, c. persson, j. sagemark, m. i. siponen, a. g. thorsell, s. van den berg, j. weigelt, m. welin, m. wikstrom, h. schueler, structural genomics consortium (sgc)
Keywords: structural genomics, structural genomics consortium, sgc, cytoplasm, endosome, phosphoprotein, protein transport, transport
- 3fpx.pdb.
oxidoreductase 06-jan-09 3fpx
Cu
Title: native fungus laccase from trametes hirsuta
Author: k. m. polyakov, t. v. fedorova, e. v. stepanova, e. a. cherkashin, s. a. kurzeev, b. v. strokopytov, v. s. lamzin, o. v. koroleva
Keywords: 4-copper protein, copper, metal-binding, oxidoreductase
- 3fq6.pdb.
transferase 07-jan-09 3fq6
Se
Title: the crystal structure of a methyltransferase domain from bacteroides thetaiotaomicron vpi
Author: k. tan, c. tesar, g. cobb, a. joachimiak, midwest center for structural genomics (mcsg)
Keywords: methyltransferase, bacteroides thetaiotaomicron vpi, structural genomics, psi-2, protein structure initiative, midwest center for structural genomics, mcsg, transferase
- 3frm.pdb.
structural genomics, unknown function 08-jan-09 3frm
Na Se
Title: the crystal structure of a functionally unknown conserved protein from staphylococcus epidermidis atcc 12228.
Author: k. tan, a. sather, s. clancy, a. joachimiak, midwest center for structural genomics (mcsg)
Keywords: conserved protein, staphylococcus epidermidis atcc 12228, structural genomics, psi-2, protein structure initiative, midwest center for structural genomics, mcsg, unknown function
- 3fs3.pdb.
chaperone 09-jan-09 3fs3
Title: crystal structure of malaria parasite nucleosome assembly protein (nap)
Author: j. gill, m. yogavel, a. kumar, h. belrhali, a. sharma
Keywords: nucleosome assembly protein, protein localization, histone recognition, structural analysis, chaperone
- 3fsg.pdb.
hydrolase 09-jan-09 3fsg
Cl Se
Title: crystal structure of alpha/beta superfamily hydrolase from oenococcus oeni psu-1
Author: b. nocek, l. bigelow, g. cobb, a. joachimiak, midwest center for structural genomics (mcsg)
Keywords: pf00561, mcsg, psi, psi-2, structural genomics, protein structure initiative, midwest center for structural genomics, hydrolase
- 3fsj.pdb.
lyase 09-jan-09 3fsj
Ca
Title: crystal structure of benzoylformate decarboxylase in complex with the inhibitor mbp
Author: g. s. brandt, g. l. kenyon, m. j. mcleish, f. jordan, g. a. petsko, d. ringe
Keywords: aromatic hydrocarbons catabolism, calcium, decarboxylase, lyase, magnesium, mandelate pathway, metal binding, thiamine pyrophosphate, metal-binding
- 3fsl.pdb.
transferase 09-jan-09 3fsl
Title: crystal structure of tyrosine aminotransferase tripple mutant (p181q,r183g,a321k) from escherichia coli at 2.35 a resolution
Author: v. n. malashkevich, b. ng, j. f. kirsch
Keywords: crystal structure, pyridoxal phosphate, internal aldimine, schiff base, amino-acid biosynthesis, aminotransferase, aromatic amino acid biosynthesis, cytoplasm, transferase
- 3ftp.pdb.
oxidoreductase 13-jan-09 3ftp
Title: crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase from burkholderia pseudomallei at 2.05 a resolution
Author: seattle structural genomics center for infectious disease (ssgcid)
Keywords: burkholderia pseudomallei, 3-ketoacyl-(acyl-carrier- protein) reductase, oxidoreductase, structural genomics, seattle structural genomics center for infectious disease
- 3fv9.pdb.
hydrolase 15-jan-09 3fv9
Mg
Title: crystal structure of putative mandelate racemase/muconatelactonizing enzyme from roseovarius nubinhibens ism complexed with magnesium
Author: v. n. malashkevich, m. rutter, k. t. bain, c. lau, s. ozyurt, d. smith, s. wasserman, m. j. sauder, s. k. burley, s. c. almo, new york structural genomix research consortium (nysgxrc)
Keywords: crystal structure, mandelate racemase/muconatelactonizing enzyme, hydrolase, psi-2, protein structure initiative, new york structural genomix research consortium, nysgxrc
- 3fvd.pdb.
hydrolase 15-jan-09 3fvd
Mg
Title: crystal structure of a member of enolase superfamily from roseovarius nubinhibens ism complexed with magnesium
Author: v. n. malashkevich, m. rutter, k. t. bain, c. lau, s. ozyurt, d. smith, s. wasserman, m. j. sauder, s. k. burley, s. c. almo, new york structural genomix research consortium (nysgxrc)
Keywords: crystal structure, hydrolase, psi-2, protein structure initiative, new york structural genomix research consortium, nysgxrc
- 3fve.pdb.
isomerase 15-jan-09 3fve
Title: crystal structure of diaminopimelate epimerase mycobacterium tuberculosis dapf
Author: v. usha, l. g. dover, d. i. roper, k. futterer, g. s. besra
Keywords: amino-acid biosynthesis, cytoplasm, isomerase, lysine biosynthesis
- 3fw2.pdb.
oxidoreductase 16-jan-09 3fw2
Se
Title: c-terminal domain of putative thiol-disulfide oxidoreductase from bacteroides thetaiotaomicron.
Author: j. osipiuk, h. li, g. cobb, a. joachimiak, midwest center for structural genomics (mcsg)
Keywords: apc61456.1, thiol-disulfide oxidoreductase, tlpa-like family, psi-2, protein structure initiative, midwest center for structural genomics, mcsg
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