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Iron-sulphur proteins

Iron-sulphur proteins in PROMISE

Iron-sulphur proteins in PROMISE

	Main entry
	Structural studies
	Reviews
c/m	Fe-S centres per monomer
c.n.	Coordination number

Protein family	Entries				Formal Fe-S core oxidation/spin states		c/m	Geometry	Ligands
Iron-sulphur proteins
Fe(Cys)4 proteins (see also Mononuclear iron proteins)
Desulforedoxin				1DXG	FeII (S=2); FeIII (S=5/2)		1	Tetrahedral	4×SCys
Desulfoferrodoxin					FeII (S=2); FeIII (S=5/2)		1	Tetrahedral	4×SCys
Rubredoxin				1CAD	FeII (S=2); FeIII (S=5/2)		1	Tetrahedral	4×SCys
Rubrerythrin				1RYT	FeII (S=2); FeIII (S=5/2)		1	Tetrahedral	4×SCys
Fe2S2 proteins
Adrenodoxin­type ferredoxins				1PUT	[Fe2S2]+ (S=1/2); [Fe2S2]2+ (S=0)		1	Diamond	4×SCys
Aromatic­ring­hydroxylating dioxygenases					[Fe2S2]+ (S=1/2); [Fe2S2]2+ (S=0)		1	Diamond	2×SCys; 2×NHis
Plant­type ferredoxins				1FRR	[Fe2S2]+ (S=1/2); [Fe2S2]2+ (S=0)		1	Diamond	4×SCys
Rieske iron-sulphur proteins				1RIE	[Fe2S2]+ (S=1/2); [Fe2S2]2+ (S=0)		1	Diamond	2×SCys; 2×NHis
Xanthine oxidase family				1ALO	[Fe2S2]+ (S=1/2); [Fe2S2]2+ (S=0)		2	Diamond	4×SCys
Fe4S4 / Fe3S4 proteins
Aconitase				7ACN	[Fe4S4]2+ (S=0) (active); [Fe3S4]+ (S=1/2) (inactive)		1	Cubane (active); cubane without one Fe vertex (inactive)	3×SCys; n×H2O; Osubstrate
Aldehyde ferredoxin oxidoreductase				1AOR	[Fe4S4]+ (S=1/2); [Fe4S4]2+ (S=0)		1	Cubane	4×SCys
Bacterial­type mono­, di­ and polycluster ferredoxins				1FXR	[Fe4S4]+ (S=1/2); [Fe4S4]2+ (S=0)		1-12	Cubane	4×SCys or 3×SCys, OAsp
					[Fe3S4]0 (S=2); [Fe3S4]+ (S=1/2)		1	Cubane without one Fe vertex	3×SCys
DMSO reductase family				1FDO	[Fe4S4]+ (S=1/2); [Fe4S4]2+ (S=0)		1	Cubane	4×SCys
Endonuclease III				2ABK	[Fe4S4]2+ (S=0) (active); [Fe3S4]+ (S=1/2) (inactive)		1	Cubane (active); cubane without one Fe vertex (inactive)	4×SCys (active); 3×SCys (inactive)
Glutamine PRPP amidotransferase				1AO0	[Fe4S4]+ (S=3/2; S=1/2; S=5/2); [Fe4S4]2+ (S=0)		1	Cubane	4×SCys
High potential iron-sulphur proteins (HiPIPs)				1ISU	[Fe4S4]2+ (S=0); [Fe4S4]3+ (S=1/2)		1	Cubane	4×SCys
Iron hydrogenase					H FS4A FS4B	[Fe4S4]+ (S=1/2); [Fe4S4]2+ (S=0)	3	Cubane	4×SCys
					FS4C	[Fe4S4]+ (admixed S=1/2, S=3/2); [Fe4S4]2+ (S=0)	0-1	Cubane	3×SCys; NHis
					FS2	[Fe2S2]+ (S=1/2); [Fe2S2]2+ (S=0)	0-1	Diamond	4×SCys
Mo­nitrogenase component I (MoFe protein), P­cluster				2MIN	[Fe8S7]N (S=0); [Fe8S7]SEMI­OX (S=1/2; S=5/2); [Fe8S7]OX1 (S=3; S=4); [Fe8S7]OX2 (S=1/2; S=7/2)		1	Two bridged cubanes sharing one S vertex	4×SCys; 2×µ­SCys; (NCys; OSer)
Mo­nitrogenase component II (Fe protein)				1NIP	[Fe4S4]0 (S=4); [Fe4S4]+ (S=1/2; S=3/2); [Fe4S4]2+ (S=0) (active)		1/2	Cubane (active)	4×SCys
					[Fe2S2]2+ (S=0) (inactive)			Diamond (inactive)
Nickel-iron hydrogenase (small subunit)				1FRV	1	[Fe4S4]+ (S=1/2); [Fe4S4]2+ (S=0)	1	Cubane	4×SCys
					2	[Fe3S4]0 (S=2); [Fe3S4]+ (S=1/2)	1	Cubane without one Fe vertex	3×SCys
					3	[Fe4S4]+ (S=1/2); [Fe4S4]2+ (S=0)	1	Cubane	3×SCys; NHis
`Prismane' protein					I	[Fe4S4]+ (quantum admixed S=3/2, S=1/2); [Fe4S4]2+ (S=0)	1	Cubane	4×SCys
					II	[Fe4S2O2X]3+ (S=1/2); [Fe4S2O2X]4+ (S=0, S=4); [Fe4S2O2X]5+ (S=9/2, S=1/2); [Fe4S2O2X]6+ (S=0)	1	Unclassified (`hybrid')	4×SCys; 2×OGlu; NHis
Sirohaem-Fe4S4 enzymes				2GEP	[Fe4S4]+ (S=1/2; spin­coupled to sirohaem); [Fe4S4]2+ (S=0)		1	Cubane	4×SCys
Trimethylamine dehydrogenase				2TMD	[Fe4S4]+ (S=1/2); [Fe4S4]2+ (S=0)		1	Cubane	4×SCys

	Main entry
	Structural studies
	Reviews
c/m	Fe-S centres per monomer
c.n.	Coordination number