TSRI's main web site PROMISE mirror at TSRI Metalloprotein DB site Created: 18 February 1998
Last modified: 15 May 1998

Diiron-carboxylate proteins in PROMISE
    M Main entry
    S Structural studies
    R Reviews
    c/m Diiron centre per monomer
    c.n. Coordination number
Protein family Entries Formal oxidation/
spin states		 c.n. Geometry Terminal ligands Bridging ligands
Diiron-carboxylate proteins M
R
Class I: Ribonucleotide reductase R2­type proteins M S R 1RIB FeII (S=2) 5 Square pyramidal NdeltaHis; eta1­OdeltaAsp or eta1­OepsilonGlu; (H2O) µ­eta1:eta1­OepsilonGlu;
µ­eta1:eta1­OepsilonGlu or
µ­eta1­OepsilonGlu
FeII (S=2) 5 Square pyramidal NdeltaHis; eta1­OepsilonGlu;
(eta2­OepsilonGlu)
FeIII (S=5/2) 6 Octahedral NdeltaHis; eta2­OdeltaAsp or eta1­OepsilonGlu; H2O µ­eta1:eta1­OepsilonGlu;
µ­O or µ­OH;
(µ­OH2)
FeIII (S=5/2) 6 Octahedral NdeltaHis; 2×eta1­OepsilonGlu; (H2O)
Class II: Ferroxidase family M
Bacterioferritin M S R 1BCF
1BFR		 FeII (S=2) 4 Tetrahedral NdeltaHis;
OepsilonGlu		 2×µ­eta1:eta1­OepsilonGlu
FeII (S=2) 4 Tetrahedral NdeltaHis; OepsilonGlu
FeIII (S=5/2) 5 Square pyramidal NdeltaHis;
OepsilonGlu; H2O 		µ­eta1:eta1­OepsilonGlu;
µ­O
FeIII (S=5/2) 5 Square pyramidal NdeltaHis;
2×OepsilonGlu
Ferritins M S
FeII (S=2);
FeIII (S=5/2)		 4 Tetrahedral NdeltaHis; eta1­OepsilonGlu and H2O or eta2­OepsilonGlu µ­eta1:eta1­OepsilonGlu
FeII (S=2);
FeIII (S=5/2)		 3
or
4		 Pyramidal or tetrahedral eta1­OepsilonGlu;
eta1­OepsilonGlu or
eta2­OepsilonGlu
Rubrerythrin M S
1RYT FeII (S=2);
FeIII (S=5/2)		 6 Octahedral eta1­OepsilonGlu;
eta2­OepsilonGlu		 2×µ­eta1:eta1­OepsilonGlu; µ­O
FeII (S=2);
FeIII (S=5/2)		 6 Octahedral NdeltaHis; eta2­OepsilonGlu
Class III: Haemerythrin family M S R 1HMO FeII (S=2);
FeIII (S=5/2)		 6 Octahedral 3×NepsilonHis µ­eta1:eta1­OdeltaAsp;
µ­eta1:eta1­OepsilonGlu;
µ­OH or µ­O
FeII (S=2);
FeIII (S=5/2)		 5-6 Square pyramidal - octahedral 2×NepsilonHis;
(OOH¯)
Class IV: Purple acid phosphatase
(M = mammalian;
P = plant)		 M S R
M FeII (S=2);
FeIII (S=5/2) 		5 Square pyramidal NdeltaHis;
eta2­OdeltaAsp or
eta2­OepsilonGlu 		µ­eta1:eta1­OdeltaAsp
or
µ­eta1:eta1­OepsilonGlu
µ­O or µ­OH
FeIII (S=5/2) 5 Square pyramidal NepsilonHis;
OetaTyr;
H2O or OH¯
1KBP P ZnII (S=0) 6 Octahedral NdeltaHis;
NepsilonHis;
OdeltaAsn;
H2O 		µ­OdeltaAsp;
µ­O or µ­OH
FeIII (S=5/2) 6 Octahedral NepsilonHis;
OetaTyr;
H2O or OH¯;
OdeltaAsp
    M Main entry
    S Structural studies
    R Reviews
    c/m Diiron centre per monomer
    c.n. Coordination number