Class I cytochromes c

Prosthetic group features
Thermodynamic properties
Class I cytochromes c in motif databases
Class I cytochromes c in alignment databases
Class I cytochromes c in 3D databases
References

Haem type	Haem iron coordination	Axial iron ligands	Formal iron oxidation/spin states
Haem c	Hexacoordinate	N_His; S_Met	Fe^II (S=0); Fe^III (S=1/2)

Cytochromes c (cyt c) can be defined as electrontransfer proteins having one or several haem c groups, bound to the protein by one or, more commonly two, thioether bonds involving sulphydryl groups of cysteine residues. The fifth haem iron ligand is always provided by a histidine residue. Cyt c possess a wide range of properties and function in a large number of different redox processes [1].

Ambler [2] recognised four classes of cyt c. Class I includes the lowspin soluble cyt c of mitochondria and bacteria, with the haemattachment site towards the Nterminus, and the sixth ligand provided by a methionine residue about 40 residues further on towards the Cterminus. Most of Class I cyt c contain a single haem c group; cyt c₄, bacterial cyt c peroxidase and the cytochrome subunit of flavocytochrome c sulphide dehydrogenase contain two haem c groups [3].

3D structures of a considerable number of Class I cyt c have been determined [1]. The proteins consist of 3-7 alpha helices; three most conserved `core' helices form a `basket' around the haem group with one haem edge exposed to the solvent (see Figure 1CRY). The dihaem cytochrome subunit of flavocytochrome c sulphide dehydrogenase contains two domains, each resembling mitochondrial cytochrome c, and has an unusual interpropionic acid linkage joining the two haem groups in the interior of the subunit [4]. Similarly, the dihaem cytochrome c peroxidase from Pseudomonas aeruginosa consists of two Class I cyt clike domains [5].

Thermodynamic properties of Class I cytochromes c

Protein	pH	ProTherm entry	Mutation	Method
Cytochrome c₂; Rhodobacter capsulatus	7.5	351	wild type	GdnHCl
		352	K12D	GdnHCl
		353	K14E	GdnHCl
		354	K32E	GdnHCl
		2210	K14E, K32E	GdnHCl
Iso1cytochrome c; Saccharomyces cerevisiae	7.5	277; 3584	wild type	GdnHCl
		278	K73M	GdnHCl
		279	K73Y	GdnHCl
		280	K73F	GdnHCl
		281; 3585	K73W	GdnHCl
		3586	K73V	GdnHCl
		3587	K73I	GdnHCl
	6.0	2742	wild type	thermal
		2743	N57I	thermal
		2960	wild type	thermal
		2961	G29S, N52I	thermal
		2962	H33P, N52I	thermal
		2963	N52I	thermal
		2964	C102S	thermal
		2965	C102A	thermal
		2966	N52A, C102A	thermal
		2967	N52G, C102A	thermal
		2968	N52I, C102A	thermal
	5.5	3561	K73W	thermal
	5.25	3560	K73W	thermal
	5.0	3550	wild type	thermal
		3559	K73W	thermal
		3570	K73V	thermal
		3579	K73I	thermal
	4.75	3549	wild type	thermal
		3558	K73W	thermal
		3569	K73V	thermal
		3578	K73I	thermal
	4.6	3510	wild type	thermal
		3511	P76L	thermal
		3512	P76G	thermal
		3513	P76V	thermal
		3514	P76R	thermal
		3515	P76S	thermal
		3516	P76Y	thermal
		3517	P76W	thermal
	4.5	3548; 3580	wild type	thermal
		3557; 3581	K73W	thermal
		3568; 3582	K73V	thermal
		3577; 3583	K73I	thermal
	4.25	3547	wild type	thermal
		3556	K73W	thermal
		3567	K73V	thermal
		3576	K73I	thermal
	4.0	3546	wild type	thermal
		3555	K73W	thermal
		3566	K73V	thermal
		3575	K73I	thermal
	3.75	3545	wild type	thermal
		3554	K73W	thermal
		3565	K73V	thermal
		3574	K73I	thermal
	3.5	3544	wild type	thermal
		3553	K73W	thermal
		3564	K73V	thermal
		3573	K73I	thermal
	3.25	3543	wild type	thermal
		3552	K73W	thermal
		3563	K73V	thermal
		3572	K73I	thermal
	3.0	3542	wild type	thermal
		3551	K73W	thermal
		3562	K73V	thermal
		3571	K73I	thermal
Iso2cytochrome c; Saccharomyces cerevisiae	7.2	3029	wild type	GdnHCl
Iso2cytochrome c; Saccharomyces cerevisiae	7.2	3030	P71T	GdnHCl

Class I cytochromes c in motif databases

PRINTS ID	PRINTS AC	PROSITE/BLOCKS ID	PROSITE AC	BLOCKS AC
CYTCHRMECIAB	PR00604	CYTOCHROME_C	PS00190	BL00190
CYTCHROMECIC	PR00605
CYTCHROMECID	PR00606
CYTCHROMECIE	PR00607

Class I cytochromes c in alignment databases

Protein Superfamily	Protein Homology Domain	Pfam	LPFC 3D alignment
00001; cytochrome c 00002; cytochrome c₄ 00005; cytochrome c₅₅₂ 03773; Pseudomonas cytochrome c peroxidase 03808; E. coli cytochrome c peroxidase 03823; cytochrome c₆	00326; cytochrome c peroxidase 00331; cytochrome c₆	PF00034; cytochrome_c	cytc cyt5

Class I cytochromes c in 3D databases

All Class I cytochromes c contain single covalently bound haem c group (see Figure 1CRY) except for ^* containing two covalently bound haem c groups per cytochrome subunit.

PDB scop BSM RELI
Base Header MMS Abstract ¹

05c1 05c1 - - Cytochrome c₅₅₅; Chlorobium thiosulfatophilum -
155c 155c 155c 155c Cytochrome c₅₅₀; Paracoccus denitrificans -
1a2s - 1a2s - Cytochrome c₆ (syn. cytochrome c₅₅₂) (oxidised); Monoraphidium braunii -
1a56 - 1a56 - Cytochrome c₅₅₂ (reduced) (NMR, mean structure refined with explicit hydrogen bond constraints); Nitrosomonas europaea -
1a8c - 1a8c - Cytochrome c₅₅₂ (reduced) (NMR, mean structure refined without hydrogen bond constraints); Nitrosomonas europaea -
1akk 1akk 1akk 1akk Cytochrome c (oxidised); horse heart -
1c2r 1c2r 1c2r 1c2r Cytochrome c₂; Rhodobacter capsulatus MMS92042
1c52 - 1c52 - Cytochrome c₅₅₂ (oxidised); Thermus thermophilus -
1c53 1c53 1c53 1c53 Cytochrome c₅₅₃; Desulfovibrio vulgaris, strain Miyazaki F MMS91032
1c6s - 1c6s - Cytochrome c₆ (syn. cytochrome c₅₅₃) (reduced); Synechococcus elongatus -
1cc5 1cc5 1cc5 1cc5 Cytochrome c₅ (oxidised); Azotobacter vinelandii -
1cch 1cch 1cch 1cch Cytochrome c₅₅₁; Pseudomonas stutzeri strain ZoBell -
1ccr 1ccr 1ccr 1ccr Cytochrome c; rice (Oryza sativa) embryo -
1ced 1ced 1ced 1ced Cytochrome c₆ (syn. cytochrome c₅₅₂) (reduced); Monoraphidium braunii -
1chh 1chh 1chh 1chh Cytochrome c (isozyme 1) (reduced) (F82Y, C102T mutant); Saccharomyces cerevisiae -
1chi 1chi 1chi 1chi Cytochrome c (isozyme 1) (reduced) (F82Y, L85A, C102T mutant); Saccharomyces cerevisiae -
1chj 1chj 1chj 1chj Cytochrome c (isozyme 1) (reduced) (L85A, C102T mutant); Saccharomyces cerevisiae -
1cie 1cie 1cie 1cie Cytochrome c (isozyme 1) (reduced) (N52I, F82S, C102A mutant); Saccharomyces cerevisiae -
1cif 1cif 1cif 1cif Cytochrome c (isozyme 1) (reduced) (R38A, F82S, C102A mutant); Saccharomyces cerevisiae -
1cig 1cig 1cig 1cig Cytochrome c (isozyme 1) (reduced) (R38A, N52I, C102A mutant); Saccharomyces cerevisiae -
1cih 1cih 1cih 1cih Cytochrome c (isozyme 1) (reduced) (R38A, N52I, F82S, C102A mutant); Saccharomyces cerevisiae -
1cor 1cor 1cor 1cor Cytochrome c₅₅₁; Pseudomonas stutzeri -
1cot 1cot 1cot 1cot Cytochrome c₂ (formerly cytochrome c₅₅₀); Paracoccus denitrificans -
1crc 1crc 1crc 1crc Cytochrome c (at low ionic strength); horse heart MS6LBC12
1crg 1crg 1crg 1crg Cytochrome c (isozyme 1) (oxidised) (N52I, C102T mutant); Saccharomyces cerevisiae -
1crh 1crh 1crh 1crh Cytochrome c (isozyme 1) (reduced) (N52I mutant); Saccharomyces cerevisiae -
1cri 1cri 1cri 1cri Cytochrome c (isozyme 1) (oxidised) (N52I, Y67F, C102T mutant); Saccharomyces cerevisiae -
1crj 1crj 1crj 1crj Cytochrome c (isozyme 1) (reduced) (N52I, Y67F, C102T mutant); Saccharomyces cerevisiae -
1cry 1cry 1cry 1cry Cytochrome c₂; Rhodopseudomonas viridis MS5NG9
1csu 1csu 1csu 1csu Cytochrome c (isozyme 1) (reduced) (L85C, C102T mutant); Saccharomyces cerevisiae -
1csv 1csv 1csv 1csv Cytochrome c (isozyme 1) (reduced) (L85F, C102T mutant); Saccharomyces cerevisiae -
1csw 1csw 1csw 1csw Cytochrome c (isozyme 1) (reduced) (L85M, C102T mutant); Saccharomyces cerevisiae -
1csx 1csx 1csx 1csx Cytochrome c (isozyme 1) (reduced) (L94S, C102T mutant); Saccharomyces cerevisiae -
1ctj 1ctj 1ctj 1ctj Cytochrome c₆; Monoraphidium braunii MS6WH4
1cty 1cty 1cty 1cty Cytochrome c (isozyme 1) (oxidised) (Y67F, C102T mutant); Saccharomyces cerevisiae -
1ctz 1ctz 1ctz 1ctz Cytochrome c (isozyme 1) (reduced) (Y67F, C102T mutant); Saccharomyces cerevisiae -
1cxa 1cxa 1cxa 1cxa Cytochrome c₂ (complex with imidazole; hexagonal form); Rhodobacter sphaeroides MS5DR5
1cxc 1cxc 1cxc 1cxc Cytochrome c₂ (tetragonal form); Rhodobacter sphaeroides MS5DR7
1cyc 1cyc 1cyc 1cyc Cytochrome c (reduced); Bonito (Katsuwonus pelamis) -
1cyi 1cyi 1cyi 1cyi Cytochrome c₆ (cytochrome c₅₅₃) (complex with Cd²⁺); Chlamydomonas reinhardtii MS6MR3
1cyj 1cyj 1cyj 1cyj Cytochrome c₆ (cytochrome c₅₅₃) (complex with Cd²⁺); Chlamydomonas reinhardtii MS6MR3

1dvh 1dvh 1dvh 1dvh Cytochrome c₅₅₃ (reduced); Desulfovibrio vulgaris MS6KSC1
1etp^* 1etp^* 1etp^* 1etp^* Cytochrome c₄; Pseudomonas stutzeri -
1fcd^* 1fcd^* 1fcd^* 1fcd^* Flavocytochrome c sulphide dehydrogenase (FCSD); Chromatium vinosum MS5MM11^*
1fhb 1fhb 1fhb 1fhb Cytochrome c (isozyme 1) (oxidised) (cyanide adduct of A80) (H39Q, M80A, C102S mutant); Saccharomyces cerevisiae -
1giw - 1giw - Cytochrome c (reduced); horse heart -
1gks 1gks 1gks 1gks Cytochrome c₅₅₁ (reduced); Ectothiorhodospira halophila MS7RBC1
1hrc 1hrc 1hrc 1hrc Cytochrome c; horse heart -
1hro 1hro 1hro 1hro Highpotential cytochrome c₂; Rhodopila globiformis -
1irv 1irv 1irv 1irv Cytochrome c (isozyme 1) (reduced) (complex with sulphate) (I75M, C102T mutant, methylated Lys72); Saccharomyces cerevisiae -
1irw 1irw 1irw 1irw Cytochrome c (isozyme 1) (reduced) (complex with sulphate) (N52A, C102T mutant, methylated Lys72); Saccharomyces cerevisiae -
1ocd 1ocd 1ocd 1ocd Cytochrome c (oxidised); horse heart -
1rap 1rap 1rap 1rap Rep A2 iso1cytochrome c (reduced) (E21D, K22Q, P25A, H26N mutant); Saccharomyces cerevisiae -
1raq 1raq 1raq 1raq Rep A2 iso1cytochrome c (reduced) (E21D, K22Q, P25A, H26N mutant); Saccharomyces cerevisiae -
1ycc 1ycc 1ycc 1ycc Cytochrome c (isozyme 1) (reduced); Saccharomyces cerevisiae -
1yea 1yea 1yea 1yea Cytochrome c (iso2) (reduced); Saccharomyces cerevisiae -
1yeb 1yeb 1yeb 1yeb Cytochrome c (B2036 composite) (reduced); Saccharomyces cerevisiae -
1yfc 1yfc 1yfc 1yfc Cytochrome c (iso1) (reduced) (C102S mutant, methylated Lys72); Saccharomyces cerevisiae MS7GA6
1yic 1yic 1yic 1yic Cytochrome c (iso1) (oxidised) (C102S mutant, methylated Lys72); Saccharomyces cerevisiae -
1ytc 1ytc 1ytc 1ytc Cytochrome c (iso2); Saccharomyces cerevisiae -
2c2c 2c2c 2c2c 2c2c Cytochrome c₂ (oxidised); Rhodospirillum rubrum -
2cxb 2cxb 2cxb 2cxb Cytochrome c₂ (triclinic form); Rhodobacter sphaeroides MS5DR6
2dvh 2dvh 2dvh 2dvh Cytochrome c₅₅₃ (Y64A mutant); Desulfovibrio vulgaris Hildenborough -
2frc 2frc 2frc 2frc Cytochrome c (reduced); horse heart MS5KS17
2giw - 2giw - Cytochrome c (reduced); horse heart -
2mta 2mta 2mta 2mta Methylamine dehydrogenase complex with amicyanin and cytochrome c_551i; Paracoccus denitrificans MS5TL2
2pac 2pac 2pac 2pac Cytochrome c₅₅₁; Pseudomonas aeruginosa MMS92044
2pcb 2pcb 2pcb 2pcb Yeast cytochrome c peroxidase (CCP) complex with horse heart cytochrome c MMS93043
2pcc 2pcc 2pcc 2pcc Yeast cytochrome c peroxidase (CCP) complex with yeast iso1cytochrome c; Saccharomyces cerevisiae MMS93044
2ycc 2ycc 2ycc 2ycc Cytochrome c (isozyme 1) (oxidised) (C102T mutant); Saccharomyces cerevisiae -
351c 351c 351c 351c Cytochrome c₅₅₁ (oxidised); Pseudomonas aeruginosa -
3c2c 3c2c 3c2c 3c2c Cytochrome c₂ (reduced); Rhodospirillum rubrum -
3cyt 3cyt 3cyt 3cyt Cytochrome c (oxidised); albacore tuna (Thunnus alalunga) heart -
451c 451c 451c 451c Cytochrome c₅₅₁ (reduced); Pseudomonas aeruginosa -
5cyt 5cyt 5cyt 5cyt Cytochrome c (reduced); albacore tuna (Thunnus alalunga) heart -
- s005 - - Dihaem cytochrome c peroxidase; Pseudomonas aeruginosa MS6DT11

PDB	scop	BSM	RELI Base	Header	¹
05c1	05c1	-	-	Cytochrome c₅₅₅; Chlorobium thiosulfatophilum	-
155c	155c	155c	155c	Cytochrome c₅₅₀; Paracoccus denitrificans	-
1a2s	-	1a2s	-	Cytochrome c₆ (syn. cytochrome c₅₅₂) (oxidised); Monoraphidium braunii	-
1a56	-	1a56	-	Cytochrome c₅₅₂ (reduced) (NMR, mean structure refined with explicit hydrogen bond constraints); Nitrosomonas europaea	-
1a8c	-	1a8c	-	Cytochrome c₅₅₂ (reduced) (NMR, mean structure refined without hydrogen bond constraints); Nitrosomonas europaea	-
1akk	1akk	1akk	1akk	Cytochrome c (oxidised); horse heart	-
1c2r	1c2r	1c2r	1c2r	Cytochrome c₂; Rhodobacter capsulatus	MMS92042
1c52	-	1c52	-	Cytochrome c₅₅₂ (oxidised); Thermus thermophilus	-
1c53	1c53	1c53	1c53	Cytochrome c₅₅₃; Desulfovibrio vulgaris, strain Miyazaki F	MMS91032
1c6s	-	1c6s	-	Cytochrome c₆ (syn. cytochrome c₅₅₃) (reduced); Synechococcus elongatus	-
1cc5	1cc5	1cc5	1cc5	Cytochrome c₅ (oxidised); Azotobacter vinelandii	-
1cch	1cch	1cch	1cch	Cytochrome c₅₅₁; Pseudomonas stutzeri strain ZoBell	-
1ccr	1ccr	1ccr	1ccr	Cytochrome c; rice (Oryza sativa) embryo	-
1ced	1ced	1ced	1ced	Cytochrome c₆ (syn. cytochrome c₅₅₂) (reduced); Monoraphidium braunii	-
1chh	1chh	1chh	1chh	Cytochrome c (isozyme 1) (reduced) (F82Y, C102T mutant); Saccharomyces cerevisiae	-
1chi	1chi	1chi	1chi	Cytochrome c (isozyme 1) (reduced) (F82Y, L85A, C102T mutant); Saccharomyces cerevisiae	-
1chj	1chj	1chj	1chj	Cytochrome c (isozyme 1) (reduced) (L85A, C102T mutant); Saccharomyces cerevisiae	-
1cie	1cie	1cie	1cie	Cytochrome c (isozyme 1) (reduced) (N52I, F82S, C102A mutant); Saccharomyces cerevisiae	-
1cif	1cif	1cif	1cif	Cytochrome c (isozyme 1) (reduced) (R38A, F82S, C102A mutant); Saccharomyces cerevisiae	-
1cig	1cig	1cig	1cig	Cytochrome c (isozyme 1) (reduced) (R38A, N52I, C102A mutant); Saccharomyces cerevisiae	-
1cih	1cih	1cih	1cih	Cytochrome c (isozyme 1) (reduced) (R38A, N52I, F82S, C102A mutant); Saccharomyces cerevisiae	-
1cor	1cor	1cor	1cor	Cytochrome c₅₅₁; Pseudomonas stutzeri	-
1cot	1cot	1cot	1cot	Cytochrome c₂ (formerly cytochrome c₅₅₀); Paracoccus denitrificans	-
1crc	1crc	1crc	1crc	Cytochrome c (at low ionic strength); horse heart	MS6LBC12
1crg	1crg	1crg	1crg	Cytochrome c (isozyme 1) (oxidised) (N52I, C102T mutant); Saccharomyces cerevisiae	-
1crh	1crh	1crh	1crh	Cytochrome c (isozyme 1) (reduced) (N52I mutant); Saccharomyces cerevisiae	-
1cri	1cri	1cri	1cri	Cytochrome c (isozyme 1) (oxidised) (N52I, Y67F, C102T mutant); Saccharomyces cerevisiae	-
1crj	1crj	1crj	1crj	Cytochrome c (isozyme 1) (reduced) (N52I, Y67F, C102T mutant); Saccharomyces cerevisiae	-
1cry	1cry	1cry	1cry	Cytochrome c₂; Rhodopseudomonas viridis	MS5NG9
1csu	1csu	1csu	1csu	Cytochrome c (isozyme 1) (reduced) (L85C, C102T mutant); Saccharomyces cerevisiae	-
1csv	1csv	1csv	1csv	Cytochrome c (isozyme 1) (reduced) (L85F, C102T mutant); Saccharomyces cerevisiae	-
1csw	1csw	1csw	1csw	Cytochrome c (isozyme 1) (reduced) (L85M, C102T mutant); Saccharomyces cerevisiae	-
1csx	1csx	1csx	1csx	Cytochrome c (isozyme 1) (reduced) (L94S, C102T mutant); Saccharomyces cerevisiae	-
1ctj	1ctj	1ctj	1ctj	Cytochrome c₆; Monoraphidium braunii	MS6WH4
1cty	1cty	1cty	1cty	Cytochrome c (isozyme 1) (oxidised) (Y67F, C102T mutant); Saccharomyces cerevisiae	-
1ctz	1ctz	1ctz	1ctz	Cytochrome c (isozyme 1) (reduced) (Y67F, C102T mutant); Saccharomyces cerevisiae	-
1cxa	1cxa	1cxa	1cxa	Cytochrome c₂ (complex with imidazole; hexagonal form); Rhodobacter sphaeroides	MS5DR5
1cxc	1cxc	1cxc	1cxc	Cytochrome c₂ (tetragonal form); Rhodobacter sphaeroides	MS5DR7
1cyc	1cyc	1cyc	1cyc	Cytochrome c (reduced); Bonito (Katsuwonus pelamis)	-
1cyi	1cyi	1cyi	1cyi	Cytochrome c₆ (cytochrome c₅₅₃) (complex with Cd²⁺); Chlamydomonas reinhardtii	MS6MR3
1cyj	1cyj	1cyj	1cyj	Cytochrome c₆ (cytochrome c₅₅₃) (complex with Cd²⁺); Chlamydomonas reinhardtii	MS6MR3
1dvh	1dvh	1dvh	1dvh	Cytochrome c₅₅₃ (reduced); Desulfovibrio vulgaris	MS6KSC1
1etp^*	1etp^*	1etp^*	1etp^*	Cytochrome c₄; Pseudomonas stutzeri	-
1fcd^*	1fcd^*	1fcd^*	1fcd^*	Flavocytochrome c sulphide dehydrogenase (FCSD); Chromatium vinosum	MS5MM11^*
1fhb	1fhb	1fhb	1fhb	Cytochrome c (isozyme 1) (oxidised) (cyanide adduct of A80) (H39Q, M80A, C102S mutant); Saccharomyces cerevisiae	-
1giw	-	1giw	-	Cytochrome c (reduced); horse heart	-
1gks	1gks	1gks	1gks	Cytochrome c₅₅₁ (reduced); Ectothiorhodospira halophila	MS7RBC1
1hrc	1hrc	1hrc	1hrc	Cytochrome c; horse heart	-
1hro	1hro	1hro	1hro	Highpotential cytochrome c₂; Rhodopila globiformis	-
1irv	1irv	1irv	1irv	Cytochrome c (isozyme 1) (reduced) (complex with sulphate) (I75M, C102T mutant, methylated Lys72); Saccharomyces cerevisiae	-
1irw	1irw	1irw	1irw	Cytochrome c (isozyme 1) (reduced) (complex with sulphate) (N52A, C102T mutant, methylated Lys72); Saccharomyces cerevisiae	-
1ocd	1ocd	1ocd	1ocd	Cytochrome c (oxidised); horse heart	-
1rap	1rap	1rap	1rap	Rep A2 iso1cytochrome c (reduced) (E21D, K22Q, P25A, H26N mutant); Saccharomyces cerevisiae	-
1raq	1raq	1raq	1raq	Rep A2 iso1cytochrome c (reduced) (E21D, K22Q, P25A, H26N mutant); Saccharomyces cerevisiae	-
1ycc	1ycc	1ycc	1ycc	Cytochrome c (isozyme 1) (reduced); Saccharomyces cerevisiae	-
1yea	1yea	1yea	1yea	Cytochrome c (iso2) (reduced); Saccharomyces cerevisiae	-
1yeb	1yeb	1yeb	1yeb	Cytochrome c (B2036 composite) (reduced); Saccharomyces cerevisiae	-
1yfc	1yfc	1yfc	1yfc	Cytochrome c (iso1) (reduced) (C102S mutant, methylated Lys72); Saccharomyces cerevisiae	MS7GA6
1yic	1yic	1yic	1yic	Cytochrome c (iso1) (oxidised) (C102S mutant, methylated Lys72); Saccharomyces cerevisiae	-
1ytc	1ytc	1ytc	1ytc	Cytochrome c (iso2); Saccharomyces cerevisiae	-
2c2c	2c2c	2c2c	2c2c	Cytochrome c₂ (oxidised); Rhodospirillum rubrum	-
2cxb	2cxb	2cxb	2cxb	Cytochrome c₂ (triclinic form); Rhodobacter sphaeroides	MS5DR6
2dvh	2dvh	2dvh	2dvh	Cytochrome c₅₅₃ (Y64A mutant); Desulfovibrio vulgaris Hildenborough	-
2frc	2frc	2frc	2frc	Cytochrome c (reduced); horse heart	MS5KS17
2giw	-	2giw	-	Cytochrome c (reduced); horse heart	-
2mta	2mta	2mta	2mta	Methylamine dehydrogenase complex with amicyanin and cytochrome c_551i; Paracoccus denitrificans	MS5TL2
2pac	2pac	2pac	2pac	Cytochrome c₅₅₁; Pseudomonas aeruginosa	MMS92044
2pcb	2pcb	2pcb	2pcb	Yeast cytochrome c peroxidase (CCP) complex with horse heart cytochrome c	MMS93043
2pcc	2pcc	2pcc	2pcc	Yeast cytochrome c peroxidase (CCP) complex with yeast iso1cytochrome c; Saccharomyces cerevisiae	MMS93044
2ycc	2ycc	2ycc	2ycc	Cytochrome c (isozyme 1) (oxidised) (C102T mutant); Saccharomyces cerevisiae	-
351c	351c	351c	351c	Cytochrome c₅₅₁ (oxidised); Pseudomonas aeruginosa	-
3c2c	3c2c	3c2c	3c2c	Cytochrome c₂ (reduced); Rhodospirillum rubrum	-
3cyt	3cyt	3cyt	3cyt	Cytochrome c (oxidised); albacore tuna (Thunnus alalunga) heart	-
451c	451c	451c	451c	Cytochrome c₅₅₁ (reduced); Pseudomonas aeruginosa	-
5cyt	5cyt	5cyt	5cyt	Cytochrome c (reduced); albacore tuna (Thunnus alalunga) heart	-
-	s005	-	-	Dihaem cytochrome c peroxidase; Pseudomonas aeruginosa	MS6DT11

¹ Macromolecular Structures abstract. Full text is available to BioMedNet Members

References

Pettigrew, G.W. and Moore, G.R. (1987) Cytochromes c. Biological Aspects. SpringerVerlag, Berlin - Heidelberg - New York.
Ambler, R.P. (1991) Sequence variability in bacterial cytochromes c. Biochim. Biophys. Acta 1058, 42-47.
van Beeumen, J. (1991) Primary structure diversity of prokaryotic diheme cytochromes c. Biochim. Biophys. Acta 1058, 56-60.
Chen, Z.W., Koh, M., van Driessche, G., van Beeumen, J.J., Bartsch, R.G., Meyer, T.E., Cusanovich, M.A. and Mathews, F.S. (1994) The structure of flavocytochrome c sulfide dehydrogenase from a purple phototrophic bacterium. Science 266, 430-432.
Fülöp, V., Ridout, C.J., Greenwood, C. and Hajdu, J. (1995) Crystal structure of the dihaem cytochrome c peroxidase from Pseudomonas aeruginosa. Structure 3, 1225-1233.