Copper proteins

Function	Protein class / family
Catalysis Copper enzymes in ENZYME database Copper enzymes in LIGAND database	Oxidoreductases Amine oxidase Ammonia monooxygenase Ascorbate oxidase Ceruloplasmin Cu,Znsuperoxide dismutase Cytochrome c oxidase Diamine oxidase Dopamine ßhydroxylase Galactose oxidase Laccase Lysyl oxidase Methane monooxygenase N₂O reductase Nitrite reductase Peptidylglycine hydroxylating monooxygenase Phenylalanine hydroxylase Tyrosinase Ubiquinone oxidase
Electron transfer	Auracyanin Azurin Phytocyanin family Plastocyanin family Rusticyanin

Copper centre	Protein class / family
Cu(N_His)₂S_CysR R = S_Met (azurin, plastocyanin, laccase) R = O_Glu (phytocyanins) R = H₂O (ceruloplasmin)	Type I (blue copper proteins) Small blue proteins Auracyanin Azurin Phytocyanin family Plastocyanin family Rusticyanin Blue oxidases Ascorbate oxidase Ceruloplasmin Laccase Nitrite reductase
Cu(N_His)_mR_n L = N, O or S ligands; R = O or S ligands m = 1 to 4; n = 0 to 3; m+n = 4 or 5	Type II Cu,Znsuperoxide dismutase Dioxygenases Monooxygenases Dopamine ßhydroxylase Methane monooxygenase Peptidylglycine hydroxylating monooxygenase Phenylalanine hydroxylase Nitrite reductase Nonblue oxidases Amine oxidase Diamine oxidase Galactose oxidase Lysyl oxidase
µO₂[Cu(N_His)₃]₂	Type III Catechol oxidase Haemocyanins Tyrosinase
Cu(N_His)₂OH·µOH[Cu(N_His)₃]₂	Trinuclear centre (type II + type III) Blue oxidases Ascorbate oxidase Ceruloplasmin Laccase
Cu₂(N_His)₂O_GluS_Met(µS_Cys)₂	Cu_A Cytochrome c oxidase N₂O reductase
CuN_His(N_His)₂L L = bridging ligand between Cu_B and Fe of haem a₃	Cu_B Cytochrome c oxidase Ubiquinone oxidase

Copper proteins
Simple	Complex
Type I only Small blue proteins Auracyanin Azurin Phytocyanin family Plastocyanin family Rusticyanin Type II only Galactose oxidase Peptidylglycine hydroxylating monooxygenase Type III only Catechol oxidase Haemocyanins Tyrosinase Type I + type II Nitrite reductase Type I + trinuclear Multicopper oxidases Ascorbate oxidase Ceruloplasmin Laccase	Haem-copper proteins Cytochrome c oxidase N₂O reductase Ubiquinone oxidase Cu-TPQ proteins Amine oxidase Diamine oxidase Lysyl oxidase Cu-Zn proteins Cu,Znsuperoxide dismutase

PRINTS ID	PRINTS AC	PROSITE/BLOCKS ID	PROSITE AC	BLOCKS AC
AMICYANIN	PR00155	COPPER_BLUE	PS00196	BL00196
COPPERBLUE	PR00156
PLASTOCYANIN	PR00157
RUSTICYANIN	PR00158
COPPERFIST	PR00617	COPPER_FIST_1 COPPER_FIST_2	PS01119 PS50073	BL01119
-	-	COX1	PS00077	BL00077
-	-	COX2	PS00078	BL00078
-	-	COX5B	PS00848	BL00848
-	-	COX10_CTAB_CYOE	PS00943	BL00943
CUDAOXIDASE	PR00766	COPPER_AMINE_OXID_1 COPPER_AMINE_OXID_1	PS01164 PS01165	BL01164
CUNO2RDTASE	PR00695	-	-	-
CUZNDISMTASE	PR00068	SOD_CU_ZN_1 SOD_CU_ZN_2	PS00087 PS00332	BL00087
DBMONOXGNASE	PR00767	CU2_MONOOXYGENASE_1 CU2_MONOOXYGENASE_2	PS00084 PS00085	BL00084
PAMONOXGNASE	PR00790	CU2_MONOOXYGENASE_1 CU2_MONOOXYGENASE_2	PS00084 PS00085	BL00084
HAEMOCYANIN	PR00187	HEMOCYANIN_1 HEMOCYANIN_2	PS00209 PS00210	BL00209
LYSYLOXIDASE	PR00074	LYSYL_OXIDASE	PS00926	BL00926
-	-	MULTICOPPER_OXIDASE1 MULTICOPPER_OXIDASE2	PS00079 PS00080	BL00079
-	-	BIOPTERIN_HYDROXYL	PS00367	BL00367
TYROSINASE	PR00092	TYROSINASE_1 TYROSINASE_2	PS00497 PS00498	BL00497
URICASE	PR00093	URICASE	PS00366	BL00366