Ribonucleotide reductase R2 structure [1, 2]

PDB	scop	BSM	RELI Base	Header	¹
1mrr*	1mrr*	1mrr*	1mrr*	Protein R2 of ribonucleotide reductase (Mn2+ substituted for Fe2+) (complex with Hg2+); Escherichia coli	MMS91110*
1rib	1rib	1rib	1rib	Protein R2 of ribonucleotide reductase; Escherichia coli	-

a	c
b	d

¹ Macromolecular Structures abstract. Full text is available to BioMedNet Members

1. Ribbon representation of the oxidised ribonucleotide reductase R2 dimer structure (PDB code 1RIB). Chain A = blue; chain B = green.
2. Ribbon representation of the oxidised ribonucleotide reductase R2 chain A structure (PDB code 1RIB). The iron site is buried in a four­­helix bundle shaded by cyan.
3. Binuclear (µ­oxo bridged) iron centre environment residues only (PDB code 1RIB; rotated 75° around y axis relative to b).
4. Binuclear iron centre environment residues (PDB code 1MRR*; orientation as c).

^* Contains a manganese­substituted binuclear centre.

References

1. Nordlund, P. and Eklund, H. (1993) Structure and function of the Escherichia coli ribonucleotide reductase protein R2. J. Mol. Biol. 232, 123-164.
2. Logan, D.T., Su, X.­D., Åberg, A., Regnström, K., Hajdu, J., Eklund, H. and Nordlund, P. (1996) Crystal structure of reduced protein R2 of ribonucleotide reductase: the structural basis for oxygen activation at a dinuclear iron site. Structure 4, 1053-1064.
3. Kraulis, P.J. (1991) MOLSCRIPT: a program to produce both detailed and schematic plots of protein structure. J. Appl. Crystallogr. 24, 946-950.

Bibliography on structural studies of ribonucleotide reductase R2­type proteins