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Last modified: 13 May 1998


Isopenicillin N synthase structure [1]

Click on image to get the corresponding picture in PostScript format. Be aware of the size of the files:
a = 175 K; b = 7 K.

PDB scop BSM RELI
Base
Header MMS Abstract ¹
1ips
-
1ips 1ips Isopenicillin N synthase (Mn2+ substituted for Fe2+); Aspergillus nidulans MS6EG5
1IPS chain A image
a
1IPS Mn centre image
b

¹ Macromolecular Structures abstract. Full text is available to BioMedNet Members

  1. Ribbon representation of the Aspergillus nidulans isopenicillin N synthase (PDB code 1IPS, chain A).
  2. Mononuclear iron centre (Mn2+ substituted for Fe2+) and its ligands.
All drawings were produced by using the program MOLSCRIPT [2].

References

  1. Roach, P.L., Clifton, I.J., Fülöp, V., Harlos, K., Barton, G.J., Hajdu, J., Andersson, I., Schofield, C.J. and Baldwin, J.E. (1995) Crystal structure of isopenicillin N synthase is the first from a new structural family of enzymes. Nature 375, 700-704.
  2. Kraulis, P.J. (1991) MOLSCRIPT: a program to produce both detailed and schematic plots of protein structure. J. Appl. Crystallogr. 24, 946-950.
Bibliography on structural studies of isopenicillin N synthase