Bacterioferritin quaternary structure [1, 2]

PDB	scop	BSM	RELI Base	Header
1bfr	1bfr	1bfr	1bfr	Bacterioferritin (cytochrome b1) (Mn2+ substituted for Fe2+) (24­mer); Escherichia coli

a
b	c

Subunit packing in bacterioferritin (PDB code 1BFR). Subunits are depicted as ribbon diagrams. Haem groups and metal atoms are not shown. Subunits pack around 2­fold axes as anti­parallel dimers (A+B, C+D, ..., U+V, W+X), which bind single haem b group (see Figure 1BCF).

1. View from the outside of the molecule down 2­fold symmetry axis; only the `upper' subunits are shown. Chain A = red; chain B = deep red; chain C = orange; chain D = pink; chain E = cyan; chain F = violet; chain G = pale green; chain H = deep green; chain I = blue; chain H = deep blue; chain Q = pale yellow; chain R = yellow; chain U = deep purple; chain V = pale purple.
2. View from the outside of the molecule down 3­fold symmetry axis (3­fold channel); subunits C, D, E, F, U and V only are shown. Colours as in a.
3. View from the outside of the molecule down 4­fold symmetry axis (4­fold channel); subunits A through H only are shown. Colours as in a.

1. Frolow, F., Kalb (Gilboa), A.J. and Yariv, J. (1994) Structure of a unique twofold symmetric haem­binding site. Nature Struct. Biol. 1, 453-460.
2. Harrison, P.M. and Arosio, P. (1996) The ferritins: molecular properties, iron storage function and cellular regulation. Biochim. Biophys. Acta 1275, 161-203.
3. Kraulis, P.J. (1991) MOLSCRIPT: a program to produce both detailed and schematic plots of protein structure. J. Appl. Crystallogr. 24, 946-950.

Bibliography on structural studies of bacterioferritin